Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | MedNEXT Journal of Medical and Health Sciences |
Texto Completo: | https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/15 |
Resumo: | Objective: To report a case of vertical herpetic meningoencephalitis. Results: The involvement of the central nervous system (CNS) in infection by HSV (herpes simplex virus), HSV-1 or HSV-2, causes an acute inflammatory process in the brain parenchyma, leading to herpetic encephalitis. It is a feared form of the disease due to its severity and its high rate of morbidity and mortality. Its rapid fatal progression can be prevented from early suspicion and treatment, which is essential when taking into account their neurological sequelae since survivors have motor sequelae, behavioral disorders, or epilepsy. The present work reports the case of a newborn male with spontaneous vaginal delivery who, at 19 days of age, started to experience fever, irritability, difficulty in eating, spasms, tremors of the upper limbs, deviation of the eyes, and seizures of difficult to control, together with CFE and serological changes, in addition to imaging tests compatible with herpetic meningoencephalitis, progressing with a very serious evolution despite the institution of specific treatment for CNS herpetic infection, evolving with important neurological sequelae. Conclusion: The sequels resulting from herpetic encephalitis not properly diagnosed, or even late, leads from severe neurological damage to death. Therefore, it is extremely important to start empirical treatment with antiviral drugs to reduce the sequelae mentioned above. |
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Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic ReviewHerpesVertical transmissionMeningoencephalitisNewbornNeonatology Objective: To report a case of vertical herpetic meningoencephalitis. Results: The involvement of the central nervous system (CNS) in infection by HSV (herpes simplex virus), HSV-1 or HSV-2, causes an acute inflammatory process in the brain parenchyma, leading to herpetic encephalitis. It is a feared form of the disease due to its severity and its high rate of morbidity and mortality. Its rapid fatal progression can be prevented from early suspicion and treatment, which is essential when taking into account their neurological sequelae since survivors have motor sequelae, behavioral disorders, or epilepsy. The present work reports the case of a newborn male with spontaneous vaginal delivery who, at 19 days of age, started to experience fever, irritability, difficulty in eating, spasms, tremors of the upper limbs, deviation of the eyes, and seizures of difficult to control, together with CFE and serological changes, in addition to imaging tests compatible with herpetic meningoencephalitis, progressing with a very serious evolution despite the institution of specific treatment for CNS herpetic infection, evolving with important neurological sequelae. Conclusion: The sequels resulting from herpetic encephalitis not properly diagnosed, or even late, leads from severe neurological damage to death. Therefore, it is extremely important to start empirical treatment with antiviral drugs to reduce the sequelae mentioned above. Faceres2020-12-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/1510.34256/mdnt2117MedNEXT Journal of Medical and Health Sciences; Vol. 2 No. 1 (2021): MedNEXT; 35–41MedNEXT Journal of Medical and Health Sciences; v. 2 n. 1 (2021): MedNEXT; 35–412763-5678reponame:MedNEXT Journal of Medical and Health Sciencesinstname:Faculdade de Medicina em São José do Rio Preto (Faceres)instacron:FACERESenghttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/15/14Copyright (c) 2021 MedNEXT Journal of Medical and Health Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessTriglia Pinto, Julia TelesTomasella Auad, Ana CarolinaMenegucci, GabriellePalácio Galbiatti, Marília GabrielaOliveira Matsuda, Ana PaulaGiometti Heredia, Gabriela MascarozAraújo, Renan Reverete deMendes, Airton JoséZotarelli Filho, Idiberto José2021-09-16T14:04:56Zoai:ojs2.mednext.zotarellifilhoscientificworks.com:article/15Revistahttps://mednext.zotarellifilhoscientificworks.com/index.php/mednextPUBhttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/oaimednextjmhs@zotarellifilhoscientificworks.com2763-56782763-5678opendoar:2021-09-16T14:04:56MedNEXT Journal of Medical and Health Sciences - Faculdade de Medicina em São José do Rio Preto (Faceres)false |
dc.title.none.fl_str_mv |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
title |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
spellingShingle |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review Triglia Pinto, Julia Teles Herpes Vertical transmission Meningoencephalitis Newborn Neonatology |
title_short |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
title_full |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
title_fullStr |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
title_full_unstemmed |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
title_sort |
Herpetic Meningoencephalitis by Vertical Transmission: A Case Report and Systematic Review |
author |
Triglia Pinto, Julia Teles |
author_facet |
Triglia Pinto, Julia Teles Tomasella Auad, Ana Carolina Menegucci, Gabrielle Palácio Galbiatti, Marília Gabriela Oliveira Matsuda, Ana Paula Giometti Heredia, Gabriela Mascaroz Araújo, Renan Reverete de Mendes, Airton José Zotarelli Filho, Idiberto José |
author_role |
author |
author2 |
Tomasella Auad, Ana Carolina Menegucci, Gabrielle Palácio Galbiatti, Marília Gabriela Oliveira Matsuda, Ana Paula Giometti Heredia, Gabriela Mascaroz Araújo, Renan Reverete de Mendes, Airton José Zotarelli Filho, Idiberto José |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Triglia Pinto, Julia Teles Tomasella Auad, Ana Carolina Menegucci, Gabrielle Palácio Galbiatti, Marília Gabriela Oliveira Matsuda, Ana Paula Giometti Heredia, Gabriela Mascaroz Araújo, Renan Reverete de Mendes, Airton José Zotarelli Filho, Idiberto José |
dc.subject.por.fl_str_mv |
Herpes Vertical transmission Meningoencephalitis Newborn Neonatology |
topic |
Herpes Vertical transmission Meningoencephalitis Newborn Neonatology |
description |
Objective: To report a case of vertical herpetic meningoencephalitis. Results: The involvement of the central nervous system (CNS) in infection by HSV (herpes simplex virus), HSV-1 or HSV-2, causes an acute inflammatory process in the brain parenchyma, leading to herpetic encephalitis. It is a feared form of the disease due to its severity and its high rate of morbidity and mortality. Its rapid fatal progression can be prevented from early suspicion and treatment, which is essential when taking into account their neurological sequelae since survivors have motor sequelae, behavioral disorders, or epilepsy. The present work reports the case of a newborn male with spontaneous vaginal delivery who, at 19 days of age, started to experience fever, irritability, difficulty in eating, spasms, tremors of the upper limbs, deviation of the eyes, and seizures of difficult to control, together with CFE and serological changes, in addition to imaging tests compatible with herpetic meningoencephalitis, progressing with a very serious evolution despite the institution of specific treatment for CNS herpetic infection, evolving with important neurological sequelae. Conclusion: The sequels resulting from herpetic encephalitis not properly diagnosed, or even late, leads from severe neurological damage to death. Therefore, it is extremely important to start empirical treatment with antiviral drugs to reduce the sequelae mentioned above. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-17 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/15 10.34256/mdnt2117 |
url |
https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/15 |
identifier_str_mv |
10.34256/mdnt2117 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/15/14 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 MedNEXT Journal of Medical and Health Sciences https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 MedNEXT Journal of Medical and Health Sciences https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Faceres |
publisher.none.fl_str_mv |
Faceres |
dc.source.none.fl_str_mv |
MedNEXT Journal of Medical and Health Sciences; Vol. 2 No. 1 (2021): MedNEXT; 35–41 MedNEXT Journal of Medical and Health Sciences; v. 2 n. 1 (2021): MedNEXT; 35–41 2763-5678 reponame:MedNEXT Journal of Medical and Health Sciences instname:Faculdade de Medicina em São José do Rio Preto (Faceres) instacron:FACERES |
instname_str |
Faculdade de Medicina em São José do Rio Preto (Faceres) |
instacron_str |
FACERES |
institution |
FACERES |
reponame_str |
MedNEXT Journal of Medical and Health Sciences |
collection |
MedNEXT Journal of Medical and Health Sciences |
repository.name.fl_str_mv |
MedNEXT Journal of Medical and Health Sciences - Faculdade de Medicina em São José do Rio Preto (Faceres) |
repository.mail.fl_str_mv |
mednextjmhs@zotarellifilhoscientificworks.com |
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