Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration

Detalhes bibliográficos
Autor(a) principal: Yaguana Galarraga, Daniel Alfonso
Data de Publicação: 2022
Outros Autores: Romero Urdiales, Luis Alonso, Manzini, Régis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: MedNEXT Journal of Medical and Health Sciences
DOI: 10.54448/mdnt22S104
Texto Completo: https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/148
Resumo: Introduction: Science has evolved at an accelerated pace in the last decades, due to the need to know more and more the human being and the environment that surrounds them. In the search for this knowledge, aiming to improve the quality of life and the treatment of diseases previously considered incurable, research, especially in the field of biotechnology, has transformed the day-to-day health professionals. The application of this biotechnology related to growth factors can be exemplified in the use of platelet-rich plasma (PRP), gel capable of modulating and accelerating some repair processes. Objective: The objective of this work was to review the concepts related to growth factors, as well as in relation to platelet-rich plasma as an adjuvant in bone regeneration therapies. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. This study focuses on the treatment of bone regeneration through platelet-rich plasma and morphogenetic protein (BMP). To this end, a survey was conducted in scientific articles in the databases PubMed, Medline, Scielo, Lilacs, and e-books. The Cochrane Instrument was used to assess the risk of bias of the included studies, and GRADE was used to classify the quality of articles to the type of study and scientific evidence. Results and Conclusion: Therefore, the use of PRP, which would accelerate the rate of bone formation, with bone morphogenetic proteins (BMPs), recombinant or autogenous, should be quite important and elucidative. The development of new research, seeking to use all known technology, will always be the best way for a short future to recognize what should be incorporated into the daily routine of medical and dental clinics, differing from what, for various reasons, whether it was just a marketing procedure or something. The greatest advantage of the use of platelet-rich plasma is its ability to accelerate the process of bone regeneration by increasing the number of growth factors present in human platelets. On the other hand, it is observed that one of its major disadvantages is the low life expectancy of these platelets in the recipient or graft bed. However, it is also known that the PRP technique would only accelerate a process of bone regeneration that normally already occurs and this process follows its path until the formation of the mature bone.
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spelling Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regenerationBone regenerationBone RemodelationPlatelet-rich plasmaBone morphogenetic proteinIntroduction: Science has evolved at an accelerated pace in the last decades, due to the need to know more and more the human being and the environment that surrounds them. In the search for this knowledge, aiming to improve the quality of life and the treatment of diseases previously considered incurable, research, especially in the field of biotechnology, has transformed the day-to-day health professionals. The application of this biotechnology related to growth factors can be exemplified in the use of platelet-rich plasma (PRP), gel capable of modulating and accelerating some repair processes. Objective: The objective of this work was to review the concepts related to growth factors, as well as in relation to platelet-rich plasma as an adjuvant in bone regeneration therapies. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. This study focuses on the treatment of bone regeneration through platelet-rich plasma and morphogenetic protein (BMP). To this end, a survey was conducted in scientific articles in the databases PubMed, Medline, Scielo, Lilacs, and e-books. The Cochrane Instrument was used to assess the risk of bias of the included studies, and GRADE was used to classify the quality of articles to the type of study and scientific evidence. Results and Conclusion: Therefore, the use of PRP, which would accelerate the rate of bone formation, with bone morphogenetic proteins (BMPs), recombinant or autogenous, should be quite important and elucidative. The development of new research, seeking to use all known technology, will always be the best way for a short future to recognize what should be incorporated into the daily routine of medical and dental clinics, differing from what, for various reasons, whether it was just a marketing procedure or something. The greatest advantage of the use of platelet-rich plasma is its ability to accelerate the process of bone regeneration by increasing the number of growth factors present in human platelets. On the other hand, it is observed that one of its major disadvantages is the low life expectancy of these platelets in the recipient or graft bed. However, it is also known that the PRP technique would only accelerate a process of bone regeneration that normally already occurs and this process follows its path until the formation of the mature bone.Faceres2022-04-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/14810.54448/mdnt22S104MedNEXT Journal of Medical and Health Sciences; Vol. 3 (2022): MedNEXT - May 2022 - Supplement 1MedNEXT Journal of Medical and Health Sciences; v. 3 (2022): MedNEXT - May 2022 - Supplement 12763-567810.54448/mdnt22S1reponame:MedNEXT Journal of Medical and Health Sciencesinstname:Faculdade de Medicina em São José do Rio Preto (Faceres)instacron:FACERESenghttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/148/139Copyright (c) 2022 MedNEXT Journal of Medical and Health Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessYaguana Galarraga, Daniel AlfonsoRomero Urdiales, Luis AlonsoManzini, Régis2022-05-05T02:52:03Zoai:ojs2.mednext.zotarellifilhoscientificworks.com:article/148Revistahttps://mednext.zotarellifilhoscientificworks.com/index.php/mednextPUBhttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/oaimednextjmhs@zotarellifilhoscientificworks.com2763-56782763-5678opendoar:2022-05-05T02:52:03MedNEXT Journal of Medical and Health Sciences - Faculdade de Medicina em São José do Rio Preto (Faceres)false
dc.title.none.fl_str_mv Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
title Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
spellingShingle Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
Yaguana Galarraga, Daniel Alfonso
Bone regeneration
Bone Remodelation
Platelet-rich plasma
Bone morphogenetic protein
Yaguana Galarraga, Daniel Alfonso
Bone regeneration
Bone Remodelation
Platelet-rich plasma
Bone morphogenetic protein
title_short Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
title_full Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
title_fullStr Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
title_full_unstemmed Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
title_sort Platelet-rich plasma and bone morphogenetic protein: bucomaxillofacial and bone regeneration
author Yaguana Galarraga, Daniel Alfonso
author_facet Yaguana Galarraga, Daniel Alfonso
Yaguana Galarraga, Daniel Alfonso
Romero Urdiales, Luis Alonso
Manzini, Régis
Romero Urdiales, Luis Alonso
Manzini, Régis
author_role author
author2 Romero Urdiales, Luis Alonso
Manzini, Régis
author2_role author
author
dc.contributor.author.fl_str_mv Yaguana Galarraga, Daniel Alfonso
Romero Urdiales, Luis Alonso
Manzini, Régis
dc.subject.por.fl_str_mv Bone regeneration
Bone Remodelation
Platelet-rich plasma
Bone morphogenetic protein
topic Bone regeneration
Bone Remodelation
Platelet-rich plasma
Bone morphogenetic protein
description Introduction: Science has evolved at an accelerated pace in the last decades, due to the need to know more and more the human being and the environment that surrounds them. In the search for this knowledge, aiming to improve the quality of life and the treatment of diseases previously considered incurable, research, especially in the field of biotechnology, has transformed the day-to-day health professionals. The application of this biotechnology related to growth factors can be exemplified in the use of platelet-rich plasma (PRP), gel capable of modulating and accelerating some repair processes. Objective: The objective of this work was to review the concepts related to growth factors, as well as in relation to platelet-rich plasma as an adjuvant in bone regeneration therapies. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. This study focuses on the treatment of bone regeneration through platelet-rich plasma and morphogenetic protein (BMP). To this end, a survey was conducted in scientific articles in the databases PubMed, Medline, Scielo, Lilacs, and e-books. The Cochrane Instrument was used to assess the risk of bias of the included studies, and GRADE was used to classify the quality of articles to the type of study and scientific evidence. Results and Conclusion: Therefore, the use of PRP, which would accelerate the rate of bone formation, with bone morphogenetic proteins (BMPs), recombinant or autogenous, should be quite important and elucidative. The development of new research, seeking to use all known technology, will always be the best way for a short future to recognize what should be incorporated into the daily routine of medical and dental clinics, differing from what, for various reasons, whether it was just a marketing procedure or something. The greatest advantage of the use of platelet-rich plasma is its ability to accelerate the process of bone regeneration by increasing the number of growth factors present in human platelets. On the other hand, it is observed that one of its major disadvantages is the low life expectancy of these platelets in the recipient or graft bed. However, it is also known that the PRP technique would only accelerate a process of bone regeneration that normally already occurs and this process follows its path until the formation of the mature bone.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/148
10.54448/mdnt22S104
url https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/148
identifier_str_mv 10.54448/mdnt22S104
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/148/139
dc.rights.driver.fl_str_mv Copyright (c) 2022 MedNEXT Journal of Medical and Health Sciences
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 MedNEXT Journal of Medical and Health Sciences
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Faceres
publisher.none.fl_str_mv Faceres
dc.source.none.fl_str_mv MedNEXT Journal of Medical and Health Sciences; Vol. 3 (2022): MedNEXT - May 2022 - Supplement 1
MedNEXT Journal of Medical and Health Sciences; v. 3 (2022): MedNEXT - May 2022 - Supplement 1
2763-5678
10.54448/mdnt22S1
reponame:MedNEXT Journal of Medical and Health Sciences
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institution FACERES
reponame_str MedNEXT Journal of Medical and Health Sciences
collection MedNEXT Journal of Medical and Health Sciences
repository.name.fl_str_mv MedNEXT Journal of Medical and Health Sciences - Faculdade de Medicina em São José do Rio Preto (Faceres)
repository.mail.fl_str_mv mednextjmhs@zotarellifilhoscientificworks.com
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dc.identifier.doi.none.fl_str_mv 10.54448/mdnt22S104