Postpartum Genital Melanoma - A Case Report

Detalhes bibliográficos
Autor(a) principal: Nai,Gisele Alborghetti
Data de Publicação: 2018
Outros Autores: Bazan,Andressa, Rocha,Caroline Andrade, Nagy,Juliana Souza, Campos,Isadora Tanaka
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista brasileira de ginecologia e obstetrícia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000300163
Resumo: Abstract Melanomas of the female genital tract may occur in the vulva, the vagina, the ovary or the cervix.Pregnancy has been considered an aggravating factor in the evolution and prognosis of melanoma. A 35-year-old female presented with vaginal bleeding 2 months after a term cesarean delivery. An endovaginal ultrasound revealed a lesion in the uterine cervix. The pathological report revealed a small round-cell neoplasm, and the immunohistochemistry confirmed the diagnosis of malignant melanoma. A positron emission tomography revealed an expansive hypermetabolic lesion centered on the cervix, and hypermetabolic lesions in the liver and right kidney. Non-surgical treatment was provided, with biochemotherapy followed by ipilimumab and nivolumab. The patient died one year later. Postpartum vaginal bleeding, even if late-onset, should be investigated, as it may be a pregnancy-associated malignant melanoma, which has a poor prognosis.
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spelling Postpartum Genital Melanoma - A Case Reportmelanomavaginal neoplasmspregnancyestrogensprognosisAbstract Melanomas of the female genital tract may occur in the vulva, the vagina, the ovary or the cervix.Pregnancy has been considered an aggravating factor in the evolution and prognosis of melanoma. A 35-year-old female presented with vaginal bleeding 2 months after a term cesarean delivery. An endovaginal ultrasound revealed a lesion in the uterine cervix. The pathological report revealed a small round-cell neoplasm, and the immunohistochemistry confirmed the diagnosis of malignant melanoma. A positron emission tomography revealed an expansive hypermetabolic lesion centered on the cervix, and hypermetabolic lesions in the liver and right kidney. Non-surgical treatment was provided, with biochemotherapy followed by ipilimumab and nivolumab. The patient died one year later. Postpartum vaginal bleeding, even if late-onset, should be investigated, as it may be a pregnancy-associated malignant melanoma, which has a poor prognosis.Federação Brasileira das Sociedades de Ginecologia e Obstetrícia2018-03-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000300163Revista Brasileira de Ginecologia e Obstetrícia v.40 n.3 2018reponame:Revista brasileira de ginecologia e obstetrícia (Online)instname:Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)instacron:FEBRASGO10.1055/s-0038-1624578info:eu-repo/semantics/openAccessNai,Gisele AlborghettiBazan,AndressaRocha,Caroline AndradeNagy,Juliana SouzaCampos,Isadora Tanakaeng2018-05-30T00:00:00Zoai:scielo:S0100-72032018000300163Revistahttp://www.scielo.br/rbgohttps://old.scielo.br/oai/scielo-oai.phppublicações@febrasgo.org.br||rbgo@fmrp.usp.br1806-93390100-7203opendoar:2018-05-30T00:00Revista brasileira de ginecologia e obstetrícia (Online) - Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)false
dc.title.none.fl_str_mv Postpartum Genital Melanoma - A Case Report
title Postpartum Genital Melanoma - A Case Report
spellingShingle Postpartum Genital Melanoma - A Case Report
Nai,Gisele Alborghetti
melanoma
vaginal neoplasms
pregnancy
estrogens
prognosis
title_short Postpartum Genital Melanoma - A Case Report
title_full Postpartum Genital Melanoma - A Case Report
title_fullStr Postpartum Genital Melanoma - A Case Report
title_full_unstemmed Postpartum Genital Melanoma - A Case Report
title_sort Postpartum Genital Melanoma - A Case Report
author Nai,Gisele Alborghetti
author_facet Nai,Gisele Alborghetti
Bazan,Andressa
Rocha,Caroline Andrade
Nagy,Juliana Souza
Campos,Isadora Tanaka
author_role author
author2 Bazan,Andressa
Rocha,Caroline Andrade
Nagy,Juliana Souza
Campos,Isadora Tanaka
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Nai,Gisele Alborghetti
Bazan,Andressa
Rocha,Caroline Andrade
Nagy,Juliana Souza
Campos,Isadora Tanaka
dc.subject.por.fl_str_mv melanoma
vaginal neoplasms
pregnancy
estrogens
prognosis
topic melanoma
vaginal neoplasms
pregnancy
estrogens
prognosis
description Abstract Melanomas of the female genital tract may occur in the vulva, the vagina, the ovary or the cervix.Pregnancy has been considered an aggravating factor in the evolution and prognosis of melanoma. A 35-year-old female presented with vaginal bleeding 2 months after a term cesarean delivery. An endovaginal ultrasound revealed a lesion in the uterine cervix. The pathological report revealed a small round-cell neoplasm, and the immunohistochemistry confirmed the diagnosis of malignant melanoma. A positron emission tomography revealed an expansive hypermetabolic lesion centered on the cervix, and hypermetabolic lesions in the liver and right kidney. Non-surgical treatment was provided, with biochemotherapy followed by ipilimumab and nivolumab. The patient died one year later. Postpartum vaginal bleeding, even if late-onset, should be investigated, as it may be a pregnancy-associated malignant melanoma, which has a poor prognosis.
publishDate 2018
dc.date.none.fl_str_mv 2018-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000300163
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000300163
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1055/s-0038-1624578
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
publisher.none.fl_str_mv Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
dc.source.none.fl_str_mv Revista Brasileira de Ginecologia e Obstetrícia v.40 n.3 2018
reponame:Revista brasileira de ginecologia e obstetrícia (Online)
instname:Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)
instacron:FEBRASGO
instname_str Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)
instacron_str FEBRASGO
institution FEBRASGO
reponame_str Revista brasileira de ginecologia e obstetrícia (Online)
collection Revista brasileira de ginecologia e obstetrícia (Online)
repository.name.fl_str_mv Revista brasileira de ginecologia e obstetrícia (Online) - Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)
repository.mail.fl_str_mv publicações@febrasgo.org.br||rbgo@fmrp.usp.br
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