Nanoemulsions formulated for topical use: a study of synthesis and toxicity
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Fitos |
Texto Completo: | https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060 |
Resumo: | Nanotechnology has stood out significantly in several areas of science, especially in the pharmaceutical field. Drug nanocarriers are considered a safe and effective alternative because they possess essential properties from the pharmacotherapeutic perspective. In this regard, nanoemulsions stand out as a vehicle for already established drugs. These are systems made up of tiny globules on a nanometric scale, which can transport the active ingredient and are still suitable for the distribution on the skin, allowing more excellent absorption. In this sense, the present review describes methodologies for the synthesis of nanoemulsions using vegetable extracts and oils, conventional allopathic medicines, and metallic nanoparticles for the composition of the formula. |
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Nanoemulsions formulated for topical use: a study of synthesis and toxicityNanoemulsões formuladas para uso tópico: estudo de síntese e toxicidadeAlopáticoNanobiotecnologiaNanopartículaÓleo vegetalAllopathicNanobiotechnologyNanoparticleVegetable oilNanotechnology has stood out significantly in several areas of science, especially in the pharmaceutical field. Drug nanocarriers are considered a safe and effective alternative because they possess essential properties from the pharmacotherapeutic perspective. In this regard, nanoemulsions stand out as a vehicle for already established drugs. These are systems made up of tiny globules on a nanometric scale, which can transport the active ingredient and are still suitable for the distribution on the skin, allowing more excellent absorption. In this sense, the present review describes methodologies for the synthesis of nanoemulsions using vegetable extracts and oils, conventional allopathic medicines, and metallic nanoparticles for the composition of the formula.A Nanotecnologia tem se destacado significativamente em diversas áreas da ciência, em especial, na área farmacêutica. Os nanocarreadores de fármacos apresentam uma alternativa segura e eficaz, apresentando propriedades importantes do ponto de vista farmacoterápico. Sob esse aspecto, destacam-se as nanoemulsões como veículo de fármacos já consagrados. Trata-se de sistemas constituídos por glóbulos bastante reduzidos, em escala manométrica, que podem veicular princípio ativo sendo ainda adequados à distribuição de substâncias ativas na pele, permitindo maior absorção. Dentro deste contexto, o presente estudo de revisão descreve metodologias de síntese de nanoemulsões utilizando para composição da fórmula, extratos e óleos vegetais, medicamentos alopáticos convencionais e nanopartículas metálicas.Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz2020-12-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/106010.32712/2446-4775.2020.1060Revista Fitos; Vol. 14 No. 4 (2020); 513-527Revista Fitos; Vol. 14 Núm. 4 (2020); 513-527Revista Fitos; v. 14 n. 4 (2020); 513-5272446-47751808-9569reponame:Revista Fitosinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060/747https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060/748Copyright (c) 2020 Revista Fitoshttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccess Porto, Alice SperandioAlmeida, Igor Vivian deVicentini, Verônica Elisa Pimenta2020-12-18T10:45:43Zoai:ojs.revistafitos.far.fiocruz.br:article/1060Revistahttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/PUBhttp://revistafitos.far.fiocruz.br/index.php/revista-fitos/oairevistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br2446-47752446-4775opendoar:2020-12-18T10:45:43Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity Nanoemulsões formuladas para uso tópico: estudo de síntese e toxicidade |
title |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity |
spellingShingle |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity Porto, Alice Sperandio Alopático Nanobiotecnologia Nanopartícula Óleo vegetal Allopathic Nanobiotechnology Nanoparticle Vegetable oil |
title_short |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity |
title_full |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity |
title_fullStr |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity |
title_full_unstemmed |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity |
title_sort |
Nanoemulsions formulated for topical use: a study of synthesis and toxicity |
author |
Porto, Alice Sperandio |
author_facet |
Porto, Alice Sperandio Almeida, Igor Vivian de Vicentini, Verônica Elisa Pimenta |
author_role |
author |
author2 |
Almeida, Igor Vivian de Vicentini, Verônica Elisa Pimenta |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Porto, Alice Sperandio Almeida, Igor Vivian de Vicentini, Verônica Elisa Pimenta |
dc.subject.por.fl_str_mv |
Alopático Nanobiotecnologia Nanopartícula Óleo vegetal Allopathic Nanobiotechnology Nanoparticle Vegetable oil |
topic |
Alopático Nanobiotecnologia Nanopartícula Óleo vegetal Allopathic Nanobiotechnology Nanoparticle Vegetable oil |
description |
Nanotechnology has stood out significantly in several areas of science, especially in the pharmaceutical field. Drug nanocarriers are considered a safe and effective alternative because they possess essential properties from the pharmacotherapeutic perspective. In this regard, nanoemulsions stand out as a vehicle for already established drugs. These are systems made up of tiny globules on a nanometric scale, which can transport the active ingredient and are still suitable for the distribution on the skin, allowing more excellent absorption. In this sense, the present review describes methodologies for the synthesis of nanoemulsions using vegetable extracts and oils, conventional allopathic medicines, and metallic nanoparticles for the composition of the formula. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060 10.32712/2446-4775.2020.1060 |
url |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060 |
identifier_str_mv |
10.32712/2446-4775.2020.1060 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060/747 https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1060/748 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Revista Fitos https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Revista Fitos https://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz |
publisher.none.fl_str_mv |
Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz |
dc.source.none.fl_str_mv |
Revista Fitos; Vol. 14 No. 4 (2020); 513-527 Revista Fitos; Vol. 14 Núm. 4 (2020); 513-527 Revista Fitos; v. 14 n. 4 (2020); 513-527 2446-4775 1808-9569 reponame:Revista Fitos instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Revista Fitos |
collection |
Revista Fitos |
repository.name.fl_str_mv |
Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
revistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br |
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