Interactions of medicinal plants and drugs in patients with systemic arterial hypertension and Diabetes mellitus

• Autor(a) principal: Ferreira, Tiago Agostinho
• Data de Publicação: 2022
• Outros Autores: Valadares, Ydia Mariele, Costa, Jullyana Bicalho, Paschoalim, Andressa Barros, Soares, Jéssica Aline Silva, Ramos, Mariana Cristina de Assis, Silva, Maria Ludmila da, Port.
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Fitos
• Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1341
• topic: Interações planta-medicamentos; Uso racional de plantas medicinais; Hipertensão arterial sistêmica; Diabetes mellitus; Plant-drug interactions; Rational use of medicinal plants; Systemic arterial hypertension; Diabetes mellitus tipo 2

The prevalence of chronic diseases such as Systemic Arterial Hypertension (SAH) and Diabetes Mellitus (DM) encourages the search for alternative treatments in addition to conventional pharmacotherapy, with emphasis on medicinal plants. However, the lack of information about medicinal plants, their interactions with drugs and self-medication are worrying factors. The objectives of the study were to identify medicinal plants and pharmacological classes used by patients with SAH and/or DM registered in the Hiperdia program in Governador Valadares, MG, to characterize these users and possible interactions between medicinal plants and a pharmacotherapy. A cross-sectional study was carried out with a semi-structured questionnaire. Of the respondents, 66.2% have SAH, 9% DM and 24.8% both pathologies. The majority (52.4%) use medicinal plants and 46.2% are subject to some type of plant-drug interaction, such as the use of Baccharis trimera, Allium sativum, Rosmarinus officinalis and Plectranthus barbatus with antihypertensives or Allium sativum and Matricaria chamomilla with oral antidiabetics. In this sense, an assessment of plant-drug interactions, adequacy of therapy and patient guidance are fundamental tools for preventing undesirable effects, contributing to the rational use of medicinal plants and improving the quality of life of patients with SAH and DM.