Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp

Detalhes bibliográficos
Autor(a) principal: Coelho, Bruna Aparecida Rezende
Data de Publicação: 2020
Outros Autores: Kent, Júlia Gori, Nunes, Adriana Marques, Feighelstein, Gloria André, Maldonado, Paulo Cezar, Nardy, Rosy de Oliveira, Barroso, Leonardo dos Santos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Fitos
Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907
Resumo: Inflammation is a response triggered in tissues vascularized against aggressive agents. The product Ferrum phosphoricum 6CH is indicated in the literature in the acute phase of inflammation with vascular and congestive alterations, mainly in the oral cavity. The aim of this study was to evaluate the action of Ferrum phosphoricum 6CH on acute inflammation of rat pulp.: Twenty-seven male rats were divided into 3 groups with 9 specimens each, submitted to pulp inflammation and treated daily according to the following distribution: Group I placebo, Group II received the drug 3 days before and Group III received homeopathic medication remaining in use after inflammatory induction. The dental pulps were obtained post-euthanasia of three rats per day, fixed and stained for histological analysis. The Groups I and II presented high levels of inflammatory intensity on the first day, with a small decrease on the second day and remaining stable on the third day. The Group III, although presenting a high level in the first day, from the second showed a decline of intensity of the picture, reaching the third day with intensity 33% lower. Ferrum phosphoricum 6CH presented anti-inflammatory action in the dental pulps of experimental animals.
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spelling Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulpAção anti-inflamatória do Ferrum Phosphoricum 6CH na polpa dentária de ratosHomeopatiaPolpa dentáriaInflamaçãoFerrum phosphoricumHomeopathyDental pulpInflammationFerrum phosphoricumInflammation is a response triggered in tissues vascularized against aggressive agents. The product Ferrum phosphoricum 6CH is indicated in the literature in the acute phase of inflammation with vascular and congestive alterations, mainly in the oral cavity. The aim of this study was to evaluate the action of Ferrum phosphoricum 6CH on acute inflammation of rat pulp.: Twenty-seven male rats were divided into 3 groups with 9 specimens each, submitted to pulp inflammation and treated daily according to the following distribution: Group I placebo, Group II received the drug 3 days before and Group III received homeopathic medication remaining in use after inflammatory induction. The dental pulps were obtained post-euthanasia of three rats per day, fixed and stained for histological analysis. The Groups I and II presented high levels of inflammatory intensity on the first day, with a small decrease on the second day and remaining stable on the third day. The Group III, although presenting a high level in the first day, from the second showed a decline of intensity of the picture, reaching the third day with intensity 33% lower. Ferrum phosphoricum 6CH presented anti-inflammatory action in the dental pulps of experimental animals.A inflamação é uma resposta desencadeada em tecidos vascularizados frente a agentes agressores. O medicamento Ferrum phosphoricum 6CH é indicado em literatura homeopática na fase aguda de inflamações com alterações vasculares e congestivas, sobretudo na cavidade oral. O objetivo desse estudo foi avaliar a ação do medicamento Ferrum phosphoricum 6CH na inflamação aguda da polpa dentária de ratos.  Selecionou-se 27 ratos machos, divididos em 3 grupos de 9 espécimes cada, foram submetidos a inflamação pulpar e tratados diariamente, assim distribuídos: Grupo I (GI), placebo; Grupo II (GII),  fármaco 3 dias antes; e Grupo III (GIII), receberam a medicação homeopática permanecendo em uso após a indução inflamatória. As polpas dentárias foram obtidas pós-eutanásia de três ratos de cada grupo por dia, fixadas e coradas para análise histológica. Os Grupos I e II apresentaram níveis elevados de intensidade inflamatória no primeiro dia, havendo pequeno decréscimo no segundo dia, mantendo-se estável no terceiro dia. O Grupo III, embora tenha apresentado nível elevado no primeiro dia, a partir do segundo apresentou declínio de intensidade do quadro, chegando ao terceiro dia com intensidade 33% menor. O Ferrum phosphoricum 6CH apresentou ação anti-inflamatória nas polpas dentais dos animais do experimento.Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz2020-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/90710.32712/2446-4775.2019.907Revista Fitos; Vol. 14 No. 3 (2020); 365-371Revista Fitos; Vol. 14 Núm. 3 (2020); 365-371Revista Fitos; v. 14 n. 3 (2020); 365-3712446-47751808-9569reponame:Revista Fitosinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907/670https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907/671Copyright (c) 2020 Revista Fitoshttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessCoelho, Bruna Aparecida RezendeKent, Júlia GoriNunes, Adriana MarquesFeighelstein, Gloria AndréMaldonado, Paulo CezarNardy, Rosy de OliveiraBarroso, Leonardo dos Santos2020-09-30T14:33:47Zoai:ojs.revistafitos.far.fiocruz.br:article/907Revistahttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/PUBhttp://revistafitos.far.fiocruz.br/index.php/revista-fitos/oairevistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br2446-47752446-4775opendoar:2020-09-30T14:33:47Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
Ação anti-inflamatória do Ferrum Phosphoricum 6CH na polpa dentária de ratos
title Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
spellingShingle Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
Coelho, Bruna Aparecida Rezende
Homeopatia
Polpa dentária
Inflamação
Ferrum phosphoricum
Homeopathy
Dental pulp
Inflammation
Ferrum phosphoricum
title_short Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
title_full Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
title_fullStr Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
title_full_unstemmed Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
title_sort Ferrum Phosphoricum 6CH anti-inflammatory action on rat dental pulp
author Coelho, Bruna Aparecida Rezende
author_facet Coelho, Bruna Aparecida Rezende
Kent, Júlia Gori
Nunes, Adriana Marques
Feighelstein, Gloria André
Maldonado, Paulo Cezar
Nardy, Rosy de Oliveira
Barroso, Leonardo dos Santos
author_role author
author2 Kent, Júlia Gori
Nunes, Adriana Marques
Feighelstein, Gloria André
Maldonado, Paulo Cezar
Nardy, Rosy de Oliveira
Barroso, Leonardo dos Santos
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Coelho, Bruna Aparecida Rezende
Kent, Júlia Gori
Nunes, Adriana Marques
Feighelstein, Gloria André
Maldonado, Paulo Cezar
Nardy, Rosy de Oliveira
Barroso, Leonardo dos Santos
dc.subject.por.fl_str_mv Homeopatia
Polpa dentária
Inflamação
Ferrum phosphoricum
Homeopathy
Dental pulp
Inflammation
Ferrum phosphoricum
topic Homeopatia
Polpa dentária
Inflamação
Ferrum phosphoricum
Homeopathy
Dental pulp
Inflammation
Ferrum phosphoricum
description Inflammation is a response triggered in tissues vascularized against aggressive agents. The product Ferrum phosphoricum 6CH is indicated in the literature in the acute phase of inflammation with vascular and congestive alterations, mainly in the oral cavity. The aim of this study was to evaluate the action of Ferrum phosphoricum 6CH on acute inflammation of rat pulp.: Twenty-seven male rats were divided into 3 groups with 9 specimens each, submitted to pulp inflammation and treated daily according to the following distribution: Group I placebo, Group II received the drug 3 days before and Group III received homeopathic medication remaining in use after inflammatory induction. The dental pulps were obtained post-euthanasia of three rats per day, fixed and stained for histological analysis. The Groups I and II presented high levels of inflammatory intensity on the first day, with a small decrease on the second day and remaining stable on the third day. The Group III, although presenting a high level in the first day, from the second showed a decline of intensity of the picture, reaching the third day with intensity 33% lower. Ferrum phosphoricum 6CH presented anti-inflammatory action in the dental pulps of experimental animals.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907
10.32712/2446-4775.2019.907
url https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907
identifier_str_mv 10.32712/2446-4775.2019.907
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907/670
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/907/671
dc.rights.driver.fl_str_mv Copyright (c) 2020 Revista Fitos
https://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Revista Fitos
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz
publisher.none.fl_str_mv Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz
dc.source.none.fl_str_mv Revista Fitos; Vol. 14 No. 3 (2020); 365-371
Revista Fitos; Vol. 14 Núm. 3 (2020); 365-371
Revista Fitos; v. 14 n. 3 (2020); 365-371
2446-4775
1808-9569
reponame:Revista Fitos
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Revista Fitos
collection Revista Fitos
repository.name.fl_str_mv Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv revistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br
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