Antioxidant potential and antimicrobial activity of the hydroethanolic extract of Ervatamia coronaria (Apocynaceae)

• Autor(a) principal: Barros, Raiane Arruda
• Data de Publicação: 2022
• Outros Autores: Sousa Júnior, Dárcio Luiz de, Caldas, Francisco Rodrigo de Lemos, Mendes, Rafael de Carvalho
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Fitos
• Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/899
• topic: Medicinal plant; Ervatamia coronary; Apocynaceae; Antioxidants; Antimicrobial; Plantas medicinais; Ervatamia coronaria; Apocynaceae; Antioxidantes; Antimicrobiano

The use of medicinal plants is a folk medicine practice performed since ancient times. Ervatamia coronaria is a shrub, native to India, in the Apocynaceae family. Crepe-jasmine as it is popularly known is used as larvicide, laxative and proteolytic. The research aimed to evaluate the antioxidant potential and antimicrobial activity of hydroethanolic extract at 70% of E. coronaria leaves. The tests were performed at the Microbiology Laboratory of the Estadio de Juazeiro do Norte Medical School. The phenolic content was determined by the Folin-Ciocalteu method, where it presented 26.15 ± 1.82 mg gallic acid equivalent / g of dry extract. The antioxidant potential was realized by the 1,1-diphenyl-2-picrylhydrazine (DPPH) radical method, where the extract showed IC 50 32.80 ± 1.10 µg / mL. Antimicrobial activity was determined by the broth microdilution method against the bacterial strains Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 9027), Salmonella enterica (ATCC 14028) and Staphylococcus aureus (ATCC 6538), where the Minimum Inhibitory Concentration (ATCC 6538) MIC) was ≥ 1024 µg/mL and was clinically irrelevant at the concentrations tested. Thus, this extract may turn out to be a candidate for becoming an antioxidant phytomedicine, but not a naturally occurring antibacterial.