Pathology selection criteria for research in Health

• Autor(a) principal: Silvério Marques, Pedro
• Data de Publicação: 2021
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Cadernos Ibero-Americanos de Direito Sanitário (Online)
• Texto Completo: https://www.cadernos.prodisa.fiocruz.br/index.php/cadernos/article/view/784
• topic: Prioridades de Pesquisa; Saúde Global; Indústria Farmacêutica; Prioridades de Investigación; Salud Global; Industria Farmacéutica; Research Priorities; Global Health; Drug Industry

We try to identify the criteria leading to the selection for investigation of certain pathologies. Its goal is to verify whether these criteria are adequate to the global health research needs and respond to the main global public health problems. We tried to confront what the published scientific information says with our own experience as a member of the Ethics Committee for Clinical Research. Most of the open access repositories consulted, refers, mostly, to specific pathologies, with few references to priorities or selection of priorities. The EuropePMC search engine, the most significant of which we have found, identifies nearly 40.000 entries. We analyzed some of the articles by the ethical, methodological approach to medical research and its priorities, namely, patient participation. Interactions between antiretroviral drugs and injecting drug use and the inclusion of drug user patients in clinical trials where only be investigated by pharmaceutical companies (and the researchers themselves), with the confrontation and pressure from the main Community Advisory Boards (CAB), in particular European CAB. The selection and arbitration between pathologies for research does not seem, comparatively, to raise interest on the part of researchers and the Academy. The research funders define the financeable areas. In pharmaceutical companies, it is the economic return, with little interest and social impact of the research results. Diseases in low-resource or rare countries and regions are not an interesting market. Multilateral organizations and global foundations have been responsible for prioritizing funding for research in areas of greatest global and social impact.