Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil

Detalhes bibliográficos
Autor(a) principal: Nascimento,Valdinete Alves do
Data de Publicação: 2016
Outros Autores: Souza,Victor Costa de, Naveca,Felipe Gomes
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000200141
Resumo: Dengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained in the city of Manaus, directly from the serum sample, applying Ion Torrent sequencing technology. The use of a massive sequencing technology allowed the detection of two variable sites, one in the coding region for the viral envelope protein and the other in the nonstructural 1 coding region within viral populations.
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spelling Complete genome of a dengue virus serotype 4 strain from Amazonas, BrazilBrazilian Amazondengue virusDENV-4viral genomenext-generation sequencingDengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained in the city of Manaus, directly from the serum sample, applying Ion Torrent sequencing technology. The use of a massive sequencing technology allowed the detection of two variable sites, one in the coding region for the viral envelope protein and the other in the nonstructural 1 coding region within viral populations.Instituto Oswaldo Cruz, Ministério da Saúde2016-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000200141Memórias do Instituto Oswaldo Cruz v.111 n.2 2016reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-02760150416info:eu-repo/semantics/openAccessNascimento,Valdinete Alves doSouza,Victor Costa deNaveca,Felipe Gomeseng2020-04-25T17:52:27Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:21:20.935Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
spellingShingle Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
Nascimento,Valdinete Alves do
Brazilian Amazon
dengue virus
DENV-4
viral genome
next-generation sequencing
title_short Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_full Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_fullStr Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_full_unstemmed Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_sort Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
author Nascimento,Valdinete Alves do
author_facet Nascimento,Valdinete Alves do
Souza,Victor Costa de
Naveca,Felipe Gomes
author_role author
author2 Souza,Victor Costa de
Naveca,Felipe Gomes
author2_role author
author
dc.contributor.author.fl_str_mv Nascimento,Valdinete Alves do
Souza,Victor Costa de
Naveca,Felipe Gomes
dc.subject.por.fl_str_mv Brazilian Amazon
dengue virus
DENV-4
viral genome
next-generation sequencing
topic Brazilian Amazon
dengue virus
DENV-4
viral genome
next-generation sequencing
dc.description.none.fl_txt_mv Dengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained in the city of Manaus, directly from the serum sample, applying Ion Torrent sequencing technology. The use of a massive sequencing technology allowed the detection of two variable sites, one in the coding region for the viral envelope protein and the other in the nonstructural 1 coding region within viral populations.
description Dengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained in the city of Manaus, directly from the serum sample, applying Ion Torrent sequencing technology. The use of a massive sequencing technology allowed the detection of two variable sites, one in the coding region for the viral envelope protein and the other in the nonstructural 1 coding region within viral populations.
publishDate 2016
dc.date.none.fl_str_mv 2016-02-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
status_str publishedVersion
format report
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000200141
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000200141
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-02760150416
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.111 n.2 2016
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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