The change of behavior of two strains of Leishmania after cultivation in a defined medium

Detalhes bibliográficos
Autor(a) principal: Melo,M. N.
Data de Publicação: 1987
Outros Autores: Williams,Paul, Rocha,N. M. Magalhães, Babá,E. H., Mayrink,W., Michalick,M. S. M., Costa,C. A da, Dias,M., Magalhães,P. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000400014
Resumo: Attempts have been made to characterize two strains of Leishmania that became infective to golden hamsters only after they had been maintained for several years in a chemically defined culture medium. Observations were made on the growth rates of promastigotes in vitro, course of infection in hamsters, morphology of amastigotes, and electrophoretic mobility patterns of eight isoenzymes. Information was obtained about the buoyant densities of n-DNA and k-DNA, and one strain was tested against monoclonal antibodies. The identity of both strains remains obscure.
id FIOCRUZ-4_36d8824eeafd01220cf74d1436326c2d
oai_identifier_str oai:scielo:S0074-02761987000400014
network_acronym_str FIOCRUZ-4
network_name_str Memórias do Instituto Oswaldo Cruz
spelling The change of behavior of two strains of Leishmania after cultivation in a defined mediumhuman cutaneous leshmaniasisin vitro growth curvesinfections in hamstersisoenzyme patternsn-DNA and k-DNAmonoclonal antibodiesAttempts have been made to characterize two strains of Leishmania that became infective to golden hamsters only after they had been maintained for several years in a chemically defined culture medium. Observations were made on the growth rates of promastigotes in vitro, course of infection in hamsters, morphology of amastigotes, and electrophoretic mobility patterns of eight isoenzymes. Information was obtained about the buoyant densities of n-DNA and k-DNA, and one strain was tested against monoclonal antibodies. The identity of both strains remains obscure.Instituto Oswaldo Cruz, Ministério da Saúde1987-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000400014Memórias do Instituto Oswaldo Cruz v.82 n.4 1987reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761987000400014info:eu-repo/semantics/openAccessMelo,M. N.Williams,PaulRocha,N. M. MagalhãesBabá,E. H.Mayrink,W.Michalick,M. S. M.Costa,C. A daDias,M.Magalhães,P. A.eng2020-04-25T17:45:55Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:01:51.417Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv The change of behavior of two strains of Leishmania after cultivation in a defined medium
title The change of behavior of two strains of Leishmania after cultivation in a defined medium
spellingShingle The change of behavior of two strains of Leishmania after cultivation in a defined medium
Melo,M. N.
human cutaneous leshmaniasis
in vitro growth curves
infections in hamsters
isoenzyme patterns
n-DNA and k-DNA
monoclonal antibodies
title_short The change of behavior of two strains of Leishmania after cultivation in a defined medium
title_full The change of behavior of two strains of Leishmania after cultivation in a defined medium
title_fullStr The change of behavior of two strains of Leishmania after cultivation in a defined medium
title_full_unstemmed The change of behavior of two strains of Leishmania after cultivation in a defined medium
title_sort The change of behavior of two strains of Leishmania after cultivation in a defined medium
author Melo,M. N.
author_facet Melo,M. N.
Williams,Paul
Rocha,N. M. Magalhães
Babá,E. H.
Mayrink,W.
Michalick,M. S. M.
Costa,C. A da
Dias,M.
Magalhães,P. A.
author_role author
author2 Williams,Paul
Rocha,N. M. Magalhães
Babá,E. H.
Mayrink,W.
Michalick,M. S. M.
Costa,C. A da
Dias,M.
Magalhães,P. A.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Melo,M. N.
Williams,Paul
Rocha,N. M. Magalhães
Babá,E. H.
Mayrink,W.
Michalick,M. S. M.
Costa,C. A da
Dias,M.
Magalhães,P. A.
dc.subject.por.fl_str_mv human cutaneous leshmaniasis
in vitro growth curves
infections in hamsters
isoenzyme patterns
n-DNA and k-DNA
monoclonal antibodies
topic human cutaneous leshmaniasis
in vitro growth curves
infections in hamsters
isoenzyme patterns
n-DNA and k-DNA
monoclonal antibodies
dc.description.none.fl_txt_mv Attempts have been made to characterize two strains of Leishmania that became infective to golden hamsters only after they had been maintained for several years in a chemically defined culture medium. Observations were made on the growth rates of promastigotes in vitro, course of infection in hamsters, morphology of amastigotes, and electrophoretic mobility patterns of eight isoenzymes. Information was obtained about the buoyant densities of n-DNA and k-DNA, and one strain was tested against monoclonal antibodies. The identity of both strains remains obscure.
description Attempts have been made to characterize two strains of Leishmania that became infective to golden hamsters only after they had been maintained for several years in a chemically defined culture medium. Observations were made on the growth rates of promastigotes in vitro, course of infection in hamsters, morphology of amastigotes, and electrophoretic mobility patterns of eight isoenzymes. Information was obtained about the buoyant densities of n-DNA and k-DNA, and one strain was tested against monoclonal antibodies. The identity of both strains remains obscure.
publishDate 1987
dc.date.none.fl_str_mv 1987-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000400014
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000400014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761987000400014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.82 n.4 1987
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
_version_ 1669937648401121280

Registros relacionados