Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi

Detalhes bibliográficos
Autor(a) principal: Cabrine-Santos,Marlene
Data de Publicação: 2003
Outros Autores: Santos,Vitorino Modesto dos, Lima,Marcus Aurelho de, Abreu,Marta Elena Araújo de, Lages-Silva,Eliane, Ramírez,Luís Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400018
Resumo: Authors describe genitourinary changes in male hamsters infected and reinfected with Trypanosoma cruzi. Changes in genital organs have been described in human and in experimental chagasic infection. Genital dysfunctions in chronic chagasic patients affect ejaculation, libido and sexual potency, and testis biopsies may show arrested maturation of germ cells, oligozoospermia and azoospermia. Sixty-five male hamsters were inoculated and reinoculated with 2x10³ trypomastigotes of T. cruzi VIC strain, and 22 non-infected animals constituted the control group. Animals were necropsied and fragments from testis, epididymis, seminal vesicle and bladder were collected and stained with hematoxylin-eosin. Peroxidase anti-peroxidase procedure was utilized to detect tissue parasitism. T. cruzi nests were found in testis, epididymis and seminal vesicle of these hamsters. Such parasitism plays a role in the origin of genital lesions observed in humans and laboratory animals during chronic chagasic infection.
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spelling Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzihamstersTrypanosoma cruzireinfectiontestisChagas diseaseAuthors describe genitourinary changes in male hamsters infected and reinfected with Trypanosoma cruzi. Changes in genital organs have been described in human and in experimental chagasic infection. Genital dysfunctions in chronic chagasic patients affect ejaculation, libido and sexual potency, and testis biopsies may show arrested maturation of germ cells, oligozoospermia and azoospermia. Sixty-five male hamsters were inoculated and reinoculated with 2x10³ trypomastigotes of T. cruzi VIC strain, and 22 non-infected animals constituted the control group. Animals were necropsied and fragments from testis, epididymis, seminal vesicle and bladder were collected and stained with hematoxylin-eosin. Peroxidase anti-peroxidase procedure was utilized to detect tissue parasitism. T. cruzi nests were found in testis, epididymis and seminal vesicle of these hamsters. Such parasitism plays a role in the origin of genital lesions observed in humans and laboratory animals during chronic chagasic infection.Instituto Oswaldo Cruz, Ministério da Saúde2003-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400018Memórias do Instituto Oswaldo Cruz v.98 n.4 2003reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762003000400018info:eu-repo/semantics/openAccessCabrine-Santos,MarleneSantos,Vitorino Modesto dosLima,Marcus Aurelho deAbreu,Marta Elena Araújo deLages-Silva,ElianeRamírez,Luís Eduardoeng2020-04-25T17:49:05Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:11:59.902Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
title Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
spellingShingle Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
Cabrine-Santos,Marlene
hamsters
Trypanosoma cruzi
reinfection
testis
Chagas disease
title_short Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
title_full Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
title_fullStr Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
title_full_unstemmed Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
title_sort Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi
author Cabrine-Santos,Marlene
author_facet Cabrine-Santos,Marlene
Santos,Vitorino Modesto dos
Lima,Marcus Aurelho de
Abreu,Marta Elena Araújo de
Lages-Silva,Eliane
Ramírez,Luís Eduardo
author_role author
author2 Santos,Vitorino Modesto dos
Lima,Marcus Aurelho de
Abreu,Marta Elena Araújo de
Lages-Silva,Eliane
Ramírez,Luís Eduardo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cabrine-Santos,Marlene
Santos,Vitorino Modesto dos
Lima,Marcus Aurelho de
Abreu,Marta Elena Araújo de
Lages-Silva,Eliane
Ramírez,Luís Eduardo
dc.subject.por.fl_str_mv hamsters
Trypanosoma cruzi
reinfection
testis
Chagas disease
topic hamsters
Trypanosoma cruzi
reinfection
testis
Chagas disease
dc.description.none.fl_txt_mv Authors describe genitourinary changes in male hamsters infected and reinfected with Trypanosoma cruzi. Changes in genital organs have been described in human and in experimental chagasic infection. Genital dysfunctions in chronic chagasic patients affect ejaculation, libido and sexual potency, and testis biopsies may show arrested maturation of germ cells, oligozoospermia and azoospermia. Sixty-five male hamsters were inoculated and reinoculated with 2x10³ trypomastigotes of T. cruzi VIC strain, and 22 non-infected animals constituted the control group. Animals were necropsied and fragments from testis, epididymis, seminal vesicle and bladder were collected and stained with hematoxylin-eosin. Peroxidase anti-peroxidase procedure was utilized to detect tissue parasitism. T. cruzi nests were found in testis, epididymis and seminal vesicle of these hamsters. Such parasitism plays a role in the origin of genital lesions observed in humans and laboratory animals during chronic chagasic infection.
description Authors describe genitourinary changes in male hamsters infected and reinfected with Trypanosoma cruzi. Changes in genital organs have been described in human and in experimental chagasic infection. Genital dysfunctions in chronic chagasic patients affect ejaculation, libido and sexual potency, and testis biopsies may show arrested maturation of germ cells, oligozoospermia and azoospermia. Sixty-five male hamsters were inoculated and reinoculated with 2x10³ trypomastigotes of T. cruzi VIC strain, and 22 non-infected animals constituted the control group. Animals were necropsied and fragments from testis, epididymis, seminal vesicle and bladder were collected and stained with hematoxylin-eosin. Peroxidase anti-peroxidase procedure was utilized to detect tissue parasitism. T. cruzi nests were found in testis, epididymis and seminal vesicle of these hamsters. Such parasitism plays a role in the origin of genital lesions observed in humans and laboratory animals during chronic chagasic infection.
publishDate 2003
dc.date.none.fl_str_mv 2003-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400018
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762003000400018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.98 n.4 2003
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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