Schistosoma mansoni: structural damage after treatment with oxamniquine

Detalhes bibliográficos
Autor(a) principal: Magalhães Filho,Ageu
Data de Publicação: 1987
Outros Autores: Melo,Maria Eliane Bezerra de, Padovan,Paulo Antônio, Padovan,Isairas Pereira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800067
Resumo: The effects of a single dose (100 mg/kg-body weight of mouse) of oxamniquine on the worm's tegument and paranchyma in relation to the process of immunological granulomatous reaction of the host's liver are described under light and electron microscopy (EM). The lesions caused by the drug are sequentially and simultaneously described in form of swelling, surface bulble and disruption with erosions. Ulceration in the tubercules with loss of spines is often more extensive and severe in male worms and concentration of host's mononuclear cells is observed. The possible role of host's immune response is discussed.
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spelling Schistosoma mansoni: structural damage after treatment with oxamniquineThe effects of a single dose (100 mg/kg-body weight of mouse) of oxamniquine on the worm's tegument and paranchyma in relation to the process of immunological granulomatous reaction of the host's liver are described under light and electron microscopy (EM). The lesions caused by the drug are sequentially and simultaneously described in form of swelling, surface bulble and disruption with erosions. Ulceration in the tubercules with loss of spines is often more extensive and severe in male worms and concentration of host's mononuclear cells is observed. The possible role of host's immune response is discussed.Instituto Oswaldo Cruz, Ministério da Saúde1987-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800067Memórias do Instituto Oswaldo Cruz v.82 suppl.4 1987reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761987000800067info:eu-repo/semantics/openAccessMagalhães Filho,AgeuMelo,Maria Eliane Bezerra dePadovan,Paulo AntônioPadovan,Isairas Pereiraeng2020-04-25T17:46:04Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:02:17.398Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Schistosoma mansoni: structural damage after treatment with oxamniquine
title Schistosoma mansoni: structural damage after treatment with oxamniquine
spellingShingle Schistosoma mansoni: structural damage after treatment with oxamniquine
Magalhães Filho,Ageu
title_short Schistosoma mansoni: structural damage after treatment with oxamniquine
title_full Schistosoma mansoni: structural damage after treatment with oxamniquine
title_fullStr Schistosoma mansoni: structural damage after treatment with oxamniquine
title_full_unstemmed Schistosoma mansoni: structural damage after treatment with oxamniquine
title_sort Schistosoma mansoni: structural damage after treatment with oxamniquine
author Magalhães Filho,Ageu
author_facet Magalhães Filho,Ageu
Melo,Maria Eliane Bezerra de
Padovan,Paulo Antônio
Padovan,Isairas Pereira
author_role author
author2 Melo,Maria Eliane Bezerra de
Padovan,Paulo Antônio
Padovan,Isairas Pereira
author2_role author
author
author
dc.contributor.author.fl_str_mv Magalhães Filho,Ageu
Melo,Maria Eliane Bezerra de
Padovan,Paulo Antônio
Padovan,Isairas Pereira
dc.description.none.fl_txt_mv The effects of a single dose (100 mg/kg-body weight of mouse) of oxamniquine on the worm's tegument and paranchyma in relation to the process of immunological granulomatous reaction of the host's liver are described under light and electron microscopy (EM). The lesions caused by the drug are sequentially and simultaneously described in form of swelling, surface bulble and disruption with erosions. Ulceration in the tubercules with loss of spines is often more extensive and severe in male worms and concentration of host's mononuclear cells is observed. The possible role of host's immune response is discussed.
description The effects of a single dose (100 mg/kg-body weight of mouse) of oxamniquine on the worm's tegument and paranchyma in relation to the process of immunological granulomatous reaction of the host's liver are described under light and electron microscopy (EM). The lesions caused by the drug are sequentially and simultaneously described in form of swelling, surface bulble and disruption with erosions. Ulceration in the tubercules with loss of spines is often more extensive and severe in male worms and concentration of host's mononuclear cells is observed. The possible role of host's immune response is discussed.
publishDate 1987
dc.date.none.fl_str_mv 1987-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800067
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800067
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761987000800067
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.82 suppl.4 1987
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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