Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals

Detalhes bibliográficos
Autor(a) principal: Lima,Thereza C. M. de
Data de Publicação: 1991
Outros Autores: Morato,Gina S., Takahashi,Reinaldo N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600035
Resumo: Petiveria alliacea (Phytolaccaceae) is a bush widely distributed in South America including Brazil, where it is popularly known as "guiné", pipi", "tipi" or "erva-de-tipi". Brazilian folk medicine attributes to the hot water infusion of its roots or leaves the following pharmacologicalproperties: antipyretic, antispasmodic, abortifacient, antirrheumatic, diuretic, analgesic and sedative. The present study has evaluated the alleged effects of P. alliacea on central nervous system (CNS), particularly, the sedative and analgesic properties of root crude aqueous extract of this plant in mice and rats. This extract showed an antinociceptive effect in acetic acid - acetylcholine - and hypertonic saline - induced abdominal constrictions, but not in hot-plate and tail flick tests P. alliacea did not produce any CNS depressor effect. Thus its antinociceptive action in animals can be responsible by its poplar use as an analgesic.
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spelling Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animalsPetiveria alliaceacrude aqueous extractcentral pharmacological actionsantinociceptive thresholdsPetiveria alliacea (Phytolaccaceae) is a bush widely distributed in South America including Brazil, where it is popularly known as "guiné", pipi", "tipi" or "erva-de-tipi". Brazilian folk medicine attributes to the hot water infusion of its roots or leaves the following pharmacologicalproperties: antipyretic, antispasmodic, abortifacient, antirrheumatic, diuretic, analgesic and sedative. The present study has evaluated the alleged effects of P. alliacea on central nervous system (CNS), particularly, the sedative and analgesic properties of root crude aqueous extract of this plant in mice and rats. This extract showed an antinociceptive effect in acetic acid - acetylcholine - and hypertonic saline - induced abdominal constrictions, but not in hot-plate and tail flick tests P. alliacea did not produce any CNS depressor effect. Thus its antinociceptive action in animals can be responsible by its poplar use as an analgesic.Instituto Oswaldo Cruz, Ministério da Saúde1991-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600035Memórias do Instituto Oswaldo Cruz v.86 suppl.2 1991reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761991000600035info:eu-repo/semantics/openAccessLima,Thereza C. M. deMorato,Gina S.Takahashi,Reinaldo N.eng2020-04-25T17:46:40Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:04:19.333Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
title Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
spellingShingle Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
Lima,Thereza C. M. de
Petiveria alliacea
crude aqueous extract
central pharmacological actions
antinociceptive thresholds
title_short Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
title_full Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
title_fullStr Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
title_full_unstemmed Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
title_sort Evaluation of antinociceptive effect of Petiveria alliacea (guiné) in animals
author Lima,Thereza C. M. de
author_facet Lima,Thereza C. M. de
Morato,Gina S.
Takahashi,Reinaldo N.
author_role author
author2 Morato,Gina S.
Takahashi,Reinaldo N.
author2_role author
author
dc.contributor.author.fl_str_mv Lima,Thereza C. M. de
Morato,Gina S.
Takahashi,Reinaldo N.
dc.subject.por.fl_str_mv Petiveria alliacea
crude aqueous extract
central pharmacological actions
antinociceptive thresholds
topic Petiveria alliacea
crude aqueous extract
central pharmacological actions
antinociceptive thresholds
dc.description.none.fl_txt_mv Petiveria alliacea (Phytolaccaceae) is a bush widely distributed in South America including Brazil, where it is popularly known as "guiné", pipi", "tipi" or "erva-de-tipi". Brazilian folk medicine attributes to the hot water infusion of its roots or leaves the following pharmacologicalproperties: antipyretic, antispasmodic, abortifacient, antirrheumatic, diuretic, analgesic and sedative. The present study has evaluated the alleged effects of P. alliacea on central nervous system (CNS), particularly, the sedative and analgesic properties of root crude aqueous extract of this plant in mice and rats. This extract showed an antinociceptive effect in acetic acid - acetylcholine - and hypertonic saline - induced abdominal constrictions, but not in hot-plate and tail flick tests P. alliacea did not produce any CNS depressor effect. Thus its antinociceptive action in animals can be responsible by its poplar use as an analgesic.
description Petiveria alliacea (Phytolaccaceae) is a bush widely distributed in South America including Brazil, where it is popularly known as "guiné", pipi", "tipi" or "erva-de-tipi". Brazilian folk medicine attributes to the hot water infusion of its roots or leaves the following pharmacologicalproperties: antipyretic, antispasmodic, abortifacient, antirrheumatic, diuretic, analgesic and sedative. The present study has evaluated the alleged effects of P. alliacea on central nervous system (CNS), particularly, the sedative and analgesic properties of root crude aqueous extract of this plant in mice and rats. This extract showed an antinociceptive effect in acetic acid - acetylcholine - and hypertonic saline - induced abdominal constrictions, but not in hot-plate and tail flick tests P. alliacea did not produce any CNS depressor effect. Thus its antinociceptive action in animals can be responsible by its poplar use as an analgesic.
publishDate 1991
dc.date.none.fl_str_mv 1991-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600035
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600035
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761991000600035
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.86 suppl.2 1991
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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