Features of host cell invasion by different infective forms of Trypanosoma cruzi

Detalhes bibliográficos
Autor(a) principal: Mortara,Renato A
Data de Publicação: 1999
Outros Autores: Procópio,Daniela O, Barros,Helena C, Verbisck,Newton V, Andreoli,Walter K, Silva,Ricardo BS, Silva,Solange da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700014
Resumo: Through its life cycle from the insect vector to mammalian hosts Trypanosoma cruzi has developed clever strategies to reach the intracellular milieu where it grows sheltered from the hosts' immune system. We have been interested in several aspects of in vitro interactions of different infective forms of the parasite with cultured mammalian cells. We have observed that not only the classically infective trypomastigotes but also amastigotes, originated from the extracellular differentiation of trypomastigotes, can infect cultured cells. Interestingly, the process of invasion of different parasite infective forms is remarkably distinct and also highly dependent on the host cell type.
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spelling Features of host cell invasion by different infective forms of Trypanosoma cruziTrypanosoma cruzicell invasionamastigotetrypomastigoteThrough its life cycle from the insect vector to mammalian hosts Trypanosoma cruzi has developed clever strategies to reach the intracellular milieu where it grows sheltered from the hosts' immune system. We have been interested in several aspects of in vitro interactions of different infective forms of the parasite with cultured mammalian cells. We have observed that not only the classically infective trypomastigotes but also amastigotes, originated from the extracellular differentiation of trypomastigotes, can infect cultured cells. Interestingly, the process of invasion of different parasite infective forms is remarkably distinct and also highly dependent on the host cell type.Instituto Oswaldo Cruz, Ministério da Saúde1999-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700014Memórias do Instituto Oswaldo Cruz v.94 suppl.1 1999reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761999000700014info:eu-repo/semantics/openAccessMortara,Renato AProcópio,Daniela OBarros,Helena CVerbisck,Newton VAndreoli,Walter KSilva,Ricardo BSSilva,Solange daeng2020-04-25T17:48:15Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:09:13.534Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Features of host cell invasion by different infective forms of Trypanosoma cruzi
title Features of host cell invasion by different infective forms of Trypanosoma cruzi
spellingShingle Features of host cell invasion by different infective forms of Trypanosoma cruzi
Mortara,Renato A
Trypanosoma cruzi
cell invasion
amastigote
trypomastigote
title_short Features of host cell invasion by different infective forms of Trypanosoma cruzi
title_full Features of host cell invasion by different infective forms of Trypanosoma cruzi
title_fullStr Features of host cell invasion by different infective forms of Trypanosoma cruzi
title_full_unstemmed Features of host cell invasion by different infective forms of Trypanosoma cruzi
title_sort Features of host cell invasion by different infective forms of Trypanosoma cruzi
author Mortara,Renato A
author_facet Mortara,Renato A
Procópio,Daniela O
Barros,Helena C
Verbisck,Newton V
Andreoli,Walter K
Silva,Ricardo BS
Silva,Solange da
author_role author
author2 Procópio,Daniela O
Barros,Helena C
Verbisck,Newton V
Andreoli,Walter K
Silva,Ricardo BS
Silva,Solange da
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mortara,Renato A
Procópio,Daniela O
Barros,Helena C
Verbisck,Newton V
Andreoli,Walter K
Silva,Ricardo BS
Silva,Solange da
dc.subject.por.fl_str_mv Trypanosoma cruzi
cell invasion
amastigote
trypomastigote
topic Trypanosoma cruzi
cell invasion
amastigote
trypomastigote
dc.description.none.fl_txt_mv Through its life cycle from the insect vector to mammalian hosts Trypanosoma cruzi has developed clever strategies to reach the intracellular milieu where it grows sheltered from the hosts' immune system. We have been interested in several aspects of in vitro interactions of different infective forms of the parasite with cultured mammalian cells. We have observed that not only the classically infective trypomastigotes but also amastigotes, originated from the extracellular differentiation of trypomastigotes, can infect cultured cells. Interestingly, the process of invasion of different parasite infective forms is remarkably distinct and also highly dependent on the host cell type.
description Through its life cycle from the insect vector to mammalian hosts Trypanosoma cruzi has developed clever strategies to reach the intracellular milieu where it grows sheltered from the hosts' immune system. We have been interested in several aspects of in vitro interactions of different infective forms of the parasite with cultured mammalian cells. We have observed that not only the classically infective trypomastigotes but also amastigotes, originated from the extracellular differentiation of trypomastigotes, can infect cultured cells. Interestingly, the process of invasion of different parasite infective forms is remarkably distinct and also highly dependent on the host cell type.
publishDate 1999
dc.date.none.fl_str_mv 1999-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700014
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761999000700014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.94 suppl.1 1999
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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