In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Memórias do Instituto Oswaldo Cruz |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013 |
Resumo: | The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family. |
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Memórias do Instituto Oswaldo Cruz |
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In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian floraacetylcholinesterase (AChE) inhibitorsAsteraceaeEuphorbiaceaeMelastomataceaeRubiaceaeSolanaceaeThe methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family.Instituto Oswaldo Cruz, Ministério da Saúde2006-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013Memórias do Instituto Oswaldo Cruz v.101 n.7 2006reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762006000700013info:eu-repo/semantics/openAccessNiño,JaimeHernández,Jimmy ACorrea,Yaned MMosquera,Oscar Meng2020-04-25T17:49:40Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:14:01.458Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
dc.title.none.fl_str_mv |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
title |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
spellingShingle |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora Niño,Jaime acetylcholinesterase (AChE) inhibitors Asteraceae Euphorbiaceae Melastomataceae Rubiaceae Solanaceae |
title_short |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
title_full |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
title_fullStr |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
title_full_unstemmed |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
title_sort |
In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora |
author |
Niño,Jaime |
author_facet |
Niño,Jaime Hernández,Jimmy A Correa,Yaned M Mosquera,Oscar M |
author_role |
author |
author2 |
Hernández,Jimmy A Correa,Yaned M Mosquera,Oscar M |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Niño,Jaime Hernández,Jimmy A Correa,Yaned M Mosquera,Oscar M |
dc.subject.por.fl_str_mv |
acetylcholinesterase (AChE) inhibitors Asteraceae Euphorbiaceae Melastomataceae Rubiaceae Solanaceae |
topic |
acetylcholinesterase (AChE) inhibitors Asteraceae Euphorbiaceae Melastomataceae Rubiaceae Solanaceae |
dc.description.none.fl_txt_mv |
The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family. |
description |
The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0074-02762006000700013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.101 n.7 2006 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
reponame_str |
Memórias do Instituto Oswaldo Cruz |
collection |
Memórias do Instituto Oswaldo Cruz |
instname_str |
Fundação Oswaldo Cruz |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
repository.name.fl_str_mv |
Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
repository.mail.fl_str_mv |
|
_version_ |
1669937697141030912 |