In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora

Detalhes bibliográficos
Autor(a) principal: Niño,Jaime
Data de Publicação: 2006
Outros Autores: Hernández,Jimmy A, Correa,Yaned M, Mosquera,Oscar M
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013
Resumo: The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family.
id FIOCRUZ-4_766bc673b396369449c3542525ab47b4
oai_identifier_str oai:scielo:S0074-02762006000700013
network_acronym_str FIOCRUZ-4
network_name_str Memórias do Instituto Oswaldo Cruz
spelling In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian floraacetylcholinesterase (AChE) inhibitorsAsteraceaeEuphorbiaceaeMelastomataceaeRubiaceaeSolanaceaeThe methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family.Instituto Oswaldo Cruz, Ministério da Saúde2006-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013Memórias do Instituto Oswaldo Cruz v.101 n.7 2006reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762006000700013info:eu-repo/semantics/openAccessNiño,JaimeHernández,Jimmy ACorrea,Yaned MMosquera,Oscar Meng2020-04-25T17:49:40Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:14:01.458Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
title In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
spellingShingle In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
Niño,Jaime
acetylcholinesterase (AChE) inhibitors
Asteraceae
Euphorbiaceae
Melastomataceae
Rubiaceae
Solanaceae
title_short In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
title_full In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
title_fullStr In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
title_full_unstemmed In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
title_sort In vitro inhibition of acetylcholinesterase by crude plant extracts from Colombian flora
author Niño,Jaime
author_facet Niño,Jaime
Hernández,Jimmy A
Correa,Yaned M
Mosquera,Oscar M
author_role author
author2 Hernández,Jimmy A
Correa,Yaned M
Mosquera,Oscar M
author2_role author
author
author
dc.contributor.author.fl_str_mv Niño,Jaime
Hernández,Jimmy A
Correa,Yaned M
Mosquera,Oscar M
dc.subject.por.fl_str_mv acetylcholinesterase (AChE) inhibitors
Asteraceae
Euphorbiaceae
Melastomataceae
Rubiaceae
Solanaceae
topic acetylcholinesterase (AChE) inhibitors
Asteraceae
Euphorbiaceae
Melastomataceae
Rubiaceae
Solanaceae
dc.description.none.fl_txt_mv The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family.
description The methanol extracts from five different plant families (Asteraceae, Euphorbiaceae, Melastomataceae, Rubiaceae, and Solanaceae) collected at Regional Natural Park Ucumarí (Colombia), were screened for their acetylcholinesterase inhibitory activity through the modified Ellman's spectrophotometric method. The best inhibitory activities on this study were shown by the extracts of Solanum leucocarpum Dunal (IC50 = 204.59 mg/l) and Witheringia coccoloboides (Damm) (IC50 = 220.68 mg/l), both plants belonging to the Solanaceae family.
publishDate 2006
dc.date.none.fl_str_mv 2006-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000700013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762006000700013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.101 n.7 2006
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
_version_ 1669937697141030912