The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus

Detalhes bibliográficos
Autor(a) principal: Vieira,Verônica V.
Data de Publicação: 1993
Outros Autores: Barrucand,Louis, Castro,Angela C. D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761993000300013
Resumo: The influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC) of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated), reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity.
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spelling The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcusgroup G Streptococcussubminimal inhibitory concentrations of antibioticspenicillinhaemolysinThe influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC) of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated), reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity.Instituto Oswaldo Cruz, Ministério da Saúde1993-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761993000300013Memórias do Instituto Oswaldo Cruz v.88 n.3 1993reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761993000300013info:eu-repo/semantics/openAccessVieira,Verônica V.Barrucand,LouisCastro,Angela C. D.eng2020-04-25T17:47:09Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:05:43.713Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
title The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
spellingShingle The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
Vieira,Verônica V.
group G Streptococcus
subminimal inhibitory concentrations of antibiotics
penicillin
haemolysin
title_short The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
title_full The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
title_fullStr The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
title_full_unstemmed The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
title_sort The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
author Vieira,Verônica V.
author_facet Vieira,Verônica V.
Barrucand,Louis
Castro,Angela C. D.
author_role author
author2 Barrucand,Louis
Castro,Angela C. D.
author2_role author
author
dc.contributor.author.fl_str_mv Vieira,Verônica V.
Barrucand,Louis
Castro,Angela C. D.
dc.subject.por.fl_str_mv group G Streptococcus
subminimal inhibitory concentrations of antibiotics
penicillin
haemolysin
topic group G Streptococcus
subminimal inhibitory concentrations of antibiotics
penicillin
haemolysin
dc.description.none.fl_txt_mv The influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC) of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated), reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity.
description The influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC) of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated), reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity.
publishDate 1993
dc.date.none.fl_str_mv 1993-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761993000300013
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761993000300013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761993000300013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.88 n.3 1993
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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