Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa

Detalhes bibliográficos
Autor(a) principal: Zanella,Louise
Data de Publicação: 2016
Outros Autores: Pina-Araujo I,Isabel de, Morgado,Mariza G, Vicente,Ana Carolina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000900594
Resumo: We characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution.
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spelling Genome-wide analyses of HTLV-1aD strains from Cape Verde, AfricaHTLV-1HTLV-1aD complete genomeHTLV-1aD signaturesCape VerdeAfricaGC ContentWe characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution.Instituto Oswaldo Cruz, Ministério da Saúde2016-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000900594Memórias do Instituto Oswaldo Cruz v.111 n.9 2016reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-02760160227info:eu-repo/semantics/openAccessZanella,LouisePina-Araujo I,Isabel deMorgado,Mariza GVicente,Ana Carolinaeng2020-04-25T17:52:23Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:21:10.992Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
title Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
spellingShingle Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
Zanella,Louise
HTLV-1
HTLV-1aD complete genome
HTLV-1aD signatures
Cape Verde
Africa
GC Content
title_short Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
title_full Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
title_fullStr Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
title_full_unstemmed Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
title_sort Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
author Zanella,Louise
author_facet Zanella,Louise
Pina-Araujo I,Isabel de
Morgado,Mariza G
Vicente,Ana Carolina
author_role author
author2 Pina-Araujo I,Isabel de
Morgado,Mariza G
Vicente,Ana Carolina
author2_role author
author
author
dc.contributor.author.fl_str_mv Zanella,Louise
Pina-Araujo I,Isabel de
Morgado,Mariza G
Vicente,Ana Carolina
dc.subject.por.fl_str_mv HTLV-1
HTLV-1aD complete genome
HTLV-1aD signatures
Cape Verde
Africa
GC Content
topic HTLV-1
HTLV-1aD complete genome
HTLV-1aD signatures
Cape Verde
Africa
GC Content
dc.description.none.fl_txt_mv We characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution.
description We characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution.
publishDate 2016
dc.date.none.fl_str_mv 2016-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000900594
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000900594
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-02760160227
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.111 n.9 2016
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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