Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil

Detalhes bibliográficos
Autor(a) principal: Kozlowski,Aline G
Data de Publicação: 2007
Outros Autores: Motta-Castro,Ana RC, Nascimento,Laura B, Silva,Ágabo MC, Teles,Sheila A, Villar,Livia M, Gaspar,Ana MC, Martins,Regina MB
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100021
Resumo: To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6% (95% CI: 72.7-78.3), ranging from 55.4 to 97.3%, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8% in the age 0-5 age group to 96.6% in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs.
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spelling Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central BrazilAfro-Brazilianhepatitis A virusprevalenceTo investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6% (95% CI: 72.7-78.3), ranging from 55.4 to 97.3%, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8% in the age 0-5 age group to 96.6% in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs.Instituto Oswaldo Cruz, Ministério da Saúde2007-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100021Memórias do Instituto Oswaldo Cruz v.102 n.1 2007reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762007000100021info:eu-repo/semantics/openAccessKozlowski,Aline GMotta-Castro,Ana RCNascimento,Laura BSilva,Ágabo MCTeles,Sheila AVillar,Livia MGaspar,Ana MCMartins,Regina MBeng2020-04-25T17:49:48Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:14:30.71Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
title Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
spellingShingle Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
Kozlowski,Aline G
Afro-Brazilian
hepatitis A virus
prevalence
title_short Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
title_full Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
title_fullStr Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
title_full_unstemmed Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
title_sort Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
author Kozlowski,Aline G
author_facet Kozlowski,Aline G
Motta-Castro,Ana RC
Nascimento,Laura B
Silva,Ágabo MC
Teles,Sheila A
Villar,Livia M
Gaspar,Ana MC
Martins,Regina MB
author_role author
author2 Motta-Castro,Ana RC
Nascimento,Laura B
Silva,Ágabo MC
Teles,Sheila A
Villar,Livia M
Gaspar,Ana MC
Martins,Regina MB
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Kozlowski,Aline G
Motta-Castro,Ana RC
Nascimento,Laura B
Silva,Ágabo MC
Teles,Sheila A
Villar,Livia M
Gaspar,Ana MC
Martins,Regina MB
dc.subject.por.fl_str_mv Afro-Brazilian
hepatitis A virus
prevalence
topic Afro-Brazilian
hepatitis A virus
prevalence
dc.description.none.fl_txt_mv To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6% (95% CI: 72.7-78.3), ranging from 55.4 to 97.3%, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8% in the age 0-5 age group to 96.6% in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs.
description To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6% (95% CI: 72.7-78.3), ranging from 55.4 to 97.3%, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8% in the age 0-5 age group to 96.6% in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs.
publishDate 2007
dc.date.none.fl_str_mv 2007-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100021
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762007000100021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.102 n.1 2007
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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