Lesões microscopicas do baço na purpura trombocitopenica idiopatica

Detalhes bibliográficos
Autor(a) principal: Riveros,Manuel
Data de Publicação: 1947
Outros Autores: Torres,C. Magarinos, Máas,Luiz Carlos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761947000300007
Resumo: Histopathological changes strikingly similar were found in the spleen of four cases (young female subjects) of idiopathic thrombocytopenic purpura hemorrhagica in which splenectomy was performed. The chief changes reported are enlargement of the marginal zone of the malpighian corpuscles, proliferation and mobilization of the reticulo-endothelial cells, myeloid metaplasia, local (tissue) eosinophilia, and stoppage of the circulation or stasis of platelets from which results a filling of the spelenic sinuses by such elements. The latter phenomenon will possibly present some bearing with thrombocytopenia which is such a characteristic feature in this disease and will perhaps account for the rapid increase in blood platelets which usually follows splenectomy and or the finding of increased megakaryocytes in the bone marrow.
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spelling Lesões microscopicas do baço na purpura trombocitopenica idiopaticaHistopathological changes strikingly similar were found in the spleen of four cases (young female subjects) of idiopathic thrombocytopenic purpura hemorrhagica in which splenectomy was performed. The chief changes reported are enlargement of the marginal zone of the malpighian corpuscles, proliferation and mobilization of the reticulo-endothelial cells, myeloid metaplasia, local (tissue) eosinophilia, and stoppage of the circulation or stasis of platelets from which results a filling of the spelenic sinuses by such elements. The latter phenomenon will possibly present some bearing with thrombocytopenia which is such a characteristic feature in this disease and will perhaps account for the rapid increase in blood platelets which usually follows splenectomy and or the finding of increased megakaryocytes in the bone marrow.Instituto Oswaldo Cruz, Ministério da Saúde1947-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761947000300007Memórias do Instituto Oswaldo Cruz v.45 n.3 1947reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761947000300007info:eu-repo/semantics/openAccessRiveros,ManuelTorres,C. MagarinosMáas,Luiz Carlospor2020-04-25T17:44:39Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 01:57:52.598Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Lesões microscopicas do baço na purpura trombocitopenica idiopatica
title Lesões microscopicas do baço na purpura trombocitopenica idiopatica
spellingShingle Lesões microscopicas do baço na purpura trombocitopenica idiopatica
Riveros,Manuel
title_short Lesões microscopicas do baço na purpura trombocitopenica idiopatica
title_full Lesões microscopicas do baço na purpura trombocitopenica idiopatica
title_fullStr Lesões microscopicas do baço na purpura trombocitopenica idiopatica
title_full_unstemmed Lesões microscopicas do baço na purpura trombocitopenica idiopatica
title_sort Lesões microscopicas do baço na purpura trombocitopenica idiopatica
author Riveros,Manuel
author_facet Riveros,Manuel
Torres,C. Magarinos
Máas,Luiz Carlos
author_role author
author2 Torres,C. Magarinos
Máas,Luiz Carlos
author2_role author
author
dc.contributor.author.fl_str_mv Riveros,Manuel
Torres,C. Magarinos
Máas,Luiz Carlos
dc.description.none.fl_txt_mv Histopathological changes strikingly similar were found in the spleen of four cases (young female subjects) of idiopathic thrombocytopenic purpura hemorrhagica in which splenectomy was performed. The chief changes reported are enlargement of the marginal zone of the malpighian corpuscles, proliferation and mobilization of the reticulo-endothelial cells, myeloid metaplasia, local (tissue) eosinophilia, and stoppage of the circulation or stasis of platelets from which results a filling of the spelenic sinuses by such elements. The latter phenomenon will possibly present some bearing with thrombocytopenia which is such a characteristic feature in this disease and will perhaps account for the rapid increase in blood platelets which usually follows splenectomy and or the finding of increased megakaryocytes in the bone marrow.
description Histopathological changes strikingly similar were found in the spleen of four cases (young female subjects) of idiopathic thrombocytopenic purpura hemorrhagica in which splenectomy was performed. The chief changes reported are enlargement of the marginal zone of the malpighian corpuscles, proliferation and mobilization of the reticulo-endothelial cells, myeloid metaplasia, local (tissue) eosinophilia, and stoppage of the circulation or stasis of platelets from which results a filling of the spelenic sinuses by such elements. The latter phenomenon will possibly present some bearing with thrombocytopenia which is such a characteristic feature in this disease and will perhaps account for the rapid increase in blood platelets which usually follows splenectomy and or the finding of increased megakaryocytes in the bone marrow.
publishDate 1947
dc.date.none.fl_str_mv 1947-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761947000300007
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761947000300007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0074-02761947000300007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.45 n.3 1947
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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