On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni

Detalhes bibliográficos
Autor(a) principal: Cabello,P. H.
Data de Publicação: 1991
Outros Autores: Krieger,H., Lopes,J. D., Sant'Ana,E. J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000100007
Resumo: The association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital. No apparent correlation between the chronic forms of the disease and the expression of those antigens was detected. However, the analysis of these date together with those observed on an Egyptian sample suggests that the presence of either of the antigens and the hepatomegalic forms of schistosomiasis is significant, without heterogeneity. Converseley, the association of histocompatibility antigens with splenogegaly is consistent and significant only for HLA-B5, but not HLA-A1
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spelling On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansonischistosomiasissusceptibility to infectionHLA system and diseaseThe association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital. No apparent correlation between the chronic forms of the disease and the expression of those antigens was detected. However, the analysis of these date together with those observed on an Egyptian sample suggests that the presence of either of the antigens and the hepatomegalic forms of schistosomiasis is significant, without heterogeneity. Converseley, the association of histocompatibility antigens with splenogegaly is consistent and significant only for HLA-B5, but not HLA-A1 Instituto Oswaldo Cruz, Ministério da Saúde1991-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000100007Memórias do Instituto Oswaldo Cruz v.86 n.1 1991reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761991000100007info:eu-repo/semantics/openAccessCabello,P. H.Krieger,H.Lopes,J. D.Sant'Ana,E. J.eng2020-04-25T17:46:33Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:03:57.116Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
title On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
spellingShingle On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
Cabello,P. H.
schistosomiasis
susceptibility to infection
HLA system and disease
title_short On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
title_full On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
title_fullStr On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
title_full_unstemmed On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
title_sort On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
author Cabello,P. H.
author_facet Cabello,P. H.
Krieger,H.
Lopes,J. D.
Sant'Ana,E. J.
author_role author
author2 Krieger,H.
Lopes,J. D.
Sant'Ana,E. J.
author2_role author
author
author
dc.contributor.author.fl_str_mv Cabello,P. H.
Krieger,H.
Lopes,J. D.
Sant'Ana,E. J.
dc.subject.por.fl_str_mv schistosomiasis
susceptibility to infection
HLA system and disease
topic schistosomiasis
susceptibility to infection
HLA system and disease
dc.description.none.fl_txt_mv The association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital. No apparent correlation between the chronic forms of the disease and the expression of those antigens was detected. However, the analysis of these date together with those observed on an Egyptian sample suggests that the presence of either of the antigens and the hepatomegalic forms of schistosomiasis is significant, without heterogeneity. Converseley, the association of histocompatibility antigens with splenogegaly is consistent and significant only for HLA-B5, but not HLA-A1
description The association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital. No apparent correlation between the chronic forms of the disease and the expression of those antigens was detected. However, the analysis of these date together with those observed on an Egyptian sample suggests that the presence of either of the antigens and the hepatomegalic forms of schistosomiasis is significant, without heterogeneity. Converseley, the association of histocompatibility antigens with splenogegaly is consistent and significant only for HLA-B5, but not HLA-A1
publishDate 1991
dc.date.none.fl_str_mv 1991-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000100007
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000100007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761991000100007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.86 n.1 1991
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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