Antimicrobial activity and chemical investigation of Brazilian Drosera

• Autor(a) principal: Ferreira,Dalva Trevisan
• Data de Publicação: 2004
• Outros Autores: Andrei,César Cornélio, Saridakis,Halha Ostrensky, Faria,Terezinha de Jesus, Vinhato,Elisângela, Carvalho,Kátia Eliane, Daniel,Juliana Feijó Souza, Machado,Sílvio Luiz, Saridakis,Dennis Panayotis, Braz-Filho,Raimundo
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Memórias do Instituto Oswaldo Cruz
• Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000700016
• topic: Drosera species; Droseraceae; antimicrobial activity; plumbagin; aliphatic compounds

The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa.