Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi

Detalhes bibliográficos
Autor(a) principal: Barbosa,Patrícia Batista Barra Medeiros
Data de Publicação: 2008
Outros Autores: Queiroz,Paula Viviane Sousa de, Jerônimo,Selma Maria B, Ximenes,Maria de Fátima Freire de Melo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762008000600006
Resumo: In order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite. Nine cavies were experimentally infected, separated into three groups and monitored at 30, 90 and 180 days, respectively. Amastigotes were identified in the spleen slides of two cavies killed 180 days after infection. Antibodies against the L. i. chagasi were identified in one of the cavies. This demonstrates that G. spixii is in fact capable of maintaining a stable infection by L. i. chagasi without alterations in biochemical and hematological parameters of the host and without perceivable micro and macroscopic lesions.
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spelling Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasiGalea spixiiLeishmania infantum chagasianimal hostsIn order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite. Nine cavies were experimentally infected, separated into three groups and monitored at 30, 90 and 180 days, respectively. Amastigotes were identified in the spleen slides of two cavies killed 180 days after infection. Antibodies against the L. i. chagasi were identified in one of the cavies. This demonstrates that G. spixii is in fact capable of maintaining a stable infection by L. i. chagasi without alterations in biochemical and hematological parameters of the host and without perceivable micro and macroscopic lesions.Instituto Oswaldo Cruz, Ministério da Saúde2008-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762008000600006Memórias do Instituto Oswaldo Cruz v.103 n.6 2008reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762008000600006info:eu-repo/semantics/openAccessBarbosa,Patrícia Batista Barra MedeirosQueiroz,Paula Viviane Sousa deJerônimo,Selma Maria BXimenes,Maria de Fátima Freire de Meloeng2020-04-25T17:50:20Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:15:44.321Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
title Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
spellingShingle Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
Barbosa,Patrícia Batista Barra Medeiros
Galea spixii
Leishmania infantum chagasi
animal hosts
title_short Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
title_full Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
title_fullStr Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
title_full_unstemmed Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
title_sort Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
author Barbosa,Patrícia Batista Barra Medeiros
author_facet Barbosa,Patrícia Batista Barra Medeiros
Queiroz,Paula Viviane Sousa de
Jerônimo,Selma Maria B
Ximenes,Maria de Fátima Freire de Melo
author_role author
author2 Queiroz,Paula Viviane Sousa de
Jerônimo,Selma Maria B
Ximenes,Maria de Fátima Freire de Melo
author2_role author
author
author
dc.contributor.author.fl_str_mv Barbosa,Patrícia Batista Barra Medeiros
Queiroz,Paula Viviane Sousa de
Jerônimo,Selma Maria B
Ximenes,Maria de Fátima Freire de Melo
dc.subject.por.fl_str_mv Galea spixii
Leishmania infantum chagasi
animal hosts
topic Galea spixii
Leishmania infantum chagasi
animal hosts
dc.description.none.fl_txt_mv In order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite. Nine cavies were experimentally infected, separated into three groups and monitored at 30, 90 and 180 days, respectively. Amastigotes were identified in the spleen slides of two cavies killed 180 days after infection. Antibodies against the L. i. chagasi were identified in one of the cavies. This demonstrates that G. spixii is in fact capable of maintaining a stable infection by L. i. chagasi without alterations in biochemical and hematological parameters of the host and without perceivable micro and macroscopic lesions.
description In order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite. Nine cavies were experimentally infected, separated into three groups and monitored at 30, 90 and 180 days, respectively. Amastigotes were identified in the spleen slides of two cavies killed 180 days after infection. Antibodies against the L. i. chagasi were identified in one of the cavies. This demonstrates that G. spixii is in fact capable of maintaining a stable infection by L. i. chagasi without alterations in biochemical and hematological parameters of the host and without perceivable micro and macroscopic lesions.
publishDate 2008
dc.date.none.fl_str_mv 2008-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762008000600006
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762008000600006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762008000600006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.103 n.6 2008
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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