Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit

Detalhes bibliográficos
Autor(a) principal: Pinto,R. Magalhães
Data de Publicação: 1990
Outros Autores: Almeida,Marília S. A., Noronha,Dely, Katz,Naftale, Tendler,Miriam
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761990000100015
Resumo: The migration of larval Schistosoma mansoni was tracked by means of autoradiographic analysis in naive rabbits percutaneously exposed to L-(**75 Se) selenomethionine-labeled cercariae on serial intervals of 1, 2, 4, 6, 8, 10, 15, 20, 25, 30, 40 and 50 days post-infection. Autoradiographic foci were detected from the 1st day in the skin, up to the 15th day in the liver. Adult and mature worms were recovered either paired or not 60 days after infection, by perfusion of hepatic and mesenteric veins. Morphometric analysis under optical microscopy, showed that worms were within regular dimention limits as compared to adult worms harboured by other host species. These observations extend previous informations on the S. mansoni-rabbit association and clearly demonstrate the post-liver phase of S.mansoni life-cycle in this host.
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spelling Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbitSchistosoma mansonimigrationautoradiographic analysisrabbit modelThe migration of larval Schistosoma mansoni was tracked by means of autoradiographic analysis in naive rabbits percutaneously exposed to L-(**75 Se) selenomethionine-labeled cercariae on serial intervals of 1, 2, 4, 6, 8, 10, 15, 20, 25, 30, 40 and 50 days post-infection. Autoradiographic foci were detected from the 1st day in the skin, up to the 15th day in the liver. Adult and mature worms were recovered either paired or not 60 days after infection, by perfusion of hepatic and mesenteric veins. Morphometric analysis under optical microscopy, showed that worms were within regular dimention limits as compared to adult worms harboured by other host species. These observations extend previous informations on the S. mansoni-rabbit association and clearly demonstrate the post-liver phase of S.mansoni life-cycle in this host.Instituto Oswaldo Cruz, Ministério da Saúde1990-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761990000100015Memórias do Instituto Oswaldo Cruz v.85 n.1 1990reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761990000100015info:eu-repo/semantics/openAccessPinto,R. MagalhãesAlmeida,Marília S. A.Noronha,DelyKatz,NaftaleTendler,Miriameng2020-04-25T17:46:28Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:03:39.504Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
title Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
spellingShingle Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
Pinto,R. Magalhães
Schistosoma mansoni
migration
autoradiographic analysis
rabbit model
title_short Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
title_full Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
title_fullStr Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
title_full_unstemmed Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
title_sort Autoradiographic analysis of Schistosoma mansoni migration in the NZ rabbit
author Pinto,R. Magalhães
author_facet Pinto,R. Magalhães
Almeida,Marília S. A.
Noronha,Dely
Katz,Naftale
Tendler,Miriam
author_role author
author2 Almeida,Marília S. A.
Noronha,Dely
Katz,Naftale
Tendler,Miriam
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pinto,R. Magalhães
Almeida,Marília S. A.
Noronha,Dely
Katz,Naftale
Tendler,Miriam
dc.subject.por.fl_str_mv Schistosoma mansoni
migration
autoradiographic analysis
rabbit model
topic Schistosoma mansoni
migration
autoradiographic analysis
rabbit model
dc.description.none.fl_txt_mv The migration of larval Schistosoma mansoni was tracked by means of autoradiographic analysis in naive rabbits percutaneously exposed to L-(**75 Se) selenomethionine-labeled cercariae on serial intervals of 1, 2, 4, 6, 8, 10, 15, 20, 25, 30, 40 and 50 days post-infection. Autoradiographic foci were detected from the 1st day in the skin, up to the 15th day in the liver. Adult and mature worms were recovered either paired or not 60 days after infection, by perfusion of hepatic and mesenteric veins. Morphometric analysis under optical microscopy, showed that worms were within regular dimention limits as compared to adult worms harboured by other host species. These observations extend previous informations on the S. mansoni-rabbit association and clearly demonstrate the post-liver phase of S.mansoni life-cycle in this host.
description The migration of larval Schistosoma mansoni was tracked by means of autoradiographic analysis in naive rabbits percutaneously exposed to L-(**75 Se) selenomethionine-labeled cercariae on serial intervals of 1, 2, 4, 6, 8, 10, 15, 20, 25, 30, 40 and 50 days post-infection. Autoradiographic foci were detected from the 1st day in the skin, up to the 15th day in the liver. Adult and mature worms were recovered either paired or not 60 days after infection, by perfusion of hepatic and mesenteric veins. Morphometric analysis under optical microscopy, showed that worms were within regular dimention limits as compared to adult worms harboured by other host species. These observations extend previous informations on the S. mansoni-rabbit association and clearly demonstrate the post-liver phase of S.mansoni life-cycle in this host.
publishDate 1990
dc.date.none.fl_str_mv 1990-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761990000100015
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761990000100015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761990000100015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.85 n.1 1990
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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