Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection

Detalhes bibliográficos
Autor(a) principal: Chamone,Munir
Data de Publicação: 1983
Outros Autores: Oliveira,L. Alves, Coelho,P. M. Z., Gazzinelli,G., Lima,A. Oliveira, Katz,Naftale
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300004
Resumo: Heterophil antibodies could be detected in sera from normal or from patient with chronic schistosomiasis. Their hemolytic activities depend on the integrity of the complement classic pathway. The heterophil antibodies from patient sera presented a higher specificity for Schistosoma mansoni antigen preparations than those detected in normal sera. Most of the hemolytic activity observed in normal sera can be destroyed at 56ºC for 4 min. On the other hand, about 80% of the sera from infected patients are partially or totally resistant to this heat-treatment. The hemolytic activities of sera were eluted from a gel filtration column in different fractions of the first peak.
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spelling Characterization of human heterophil hemolysins induced by Schistosoma mansoni infectionHeterophil antibodies could be detected in sera from normal or from patient with chronic schistosomiasis. Their hemolytic activities depend on the integrity of the complement classic pathway. The heterophil antibodies from patient sera presented a higher specificity for Schistosoma mansoni antigen preparations than those detected in normal sera. Most of the hemolytic activity observed in normal sera can be destroyed at 56ºC for 4 min. On the other hand, about 80% of the sera from infected patients are partially or totally resistant to this heat-treatment. The hemolytic activities of sera were eluted from a gel filtration column in different fractions of the first peak.Instituto Oswaldo Cruz, Ministério da Saúde1983-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300004Memórias do Instituto Oswaldo Cruz v.78 n.3 1983reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761983000300004info:eu-repo/semantics/openAccessChamone,MunirOliveira,L. AlvesCoelho,P. M. Z.Gazzinelli,G.Lima,A. OliveiraKatz,Naftaleeng2020-04-25T17:45:30Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:00:34.09Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
title Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
spellingShingle Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
Chamone,Munir
title_short Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
title_full Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
title_fullStr Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
title_full_unstemmed Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
title_sort Characterization of human heterophil hemolysins induced by Schistosoma mansoni infection
author Chamone,Munir
author_facet Chamone,Munir
Oliveira,L. Alves
Coelho,P. M. Z.
Gazzinelli,G.
Lima,A. Oliveira
Katz,Naftale
author_role author
author2 Oliveira,L. Alves
Coelho,P. M. Z.
Gazzinelli,G.
Lima,A. Oliveira
Katz,Naftale
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Chamone,Munir
Oliveira,L. Alves
Coelho,P. M. Z.
Gazzinelli,G.
Lima,A. Oliveira
Katz,Naftale
dc.description.none.fl_txt_mv Heterophil antibodies could be detected in sera from normal or from patient with chronic schistosomiasis. Their hemolytic activities depend on the integrity of the complement classic pathway. The heterophil antibodies from patient sera presented a higher specificity for Schistosoma mansoni antigen preparations than those detected in normal sera. Most of the hemolytic activity observed in normal sera can be destroyed at 56ºC for 4 min. On the other hand, about 80% of the sera from infected patients are partially or totally resistant to this heat-treatment. The hemolytic activities of sera were eluted from a gel filtration column in different fractions of the first peak.
description Heterophil antibodies could be detected in sera from normal or from patient with chronic schistosomiasis. Their hemolytic activities depend on the integrity of the complement classic pathway. The heterophil antibodies from patient sera presented a higher specificity for Schistosoma mansoni antigen preparations than those detected in normal sera. Most of the hemolytic activity observed in normal sera can be destroyed at 56ºC for 4 min. On the other hand, about 80% of the sera from infected patients are partially or totally resistant to this heat-treatment. The hemolytic activities of sera were eluted from a gel filtration column in different fractions of the first peak.
publishDate 1983
dc.date.none.fl_str_mv 1983-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300004
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761983000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.78 n.3 1983
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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