Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil

Detalhes bibliográficos
Autor(a) principal: Costa,Carlos Henrique Nery
Data de Publicação: 2008
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2008001200027
Resumo: The available hypotheses or explanations for the urbanization of American visceral leishmaniasis are insufficient. An alternative hypothesis is that changes in the ecology and biology of the vector, Lutzomyia longipalpis, might explain all the new urban epidemiological features of the disease. To tackle the knowledge gaps in this process, certain key research areas need to be prioritized: the role of dogs in expanding transmission in cities, community trials to evaluate new insecticides, and research on the ecological and molecular determinants of Leishmania chagasi transmission. Investment of public funds should focus on the development of a human vaccine, since such a vaccine now appears to be within reach. Even small effects from a vaccine could substantially reduce the impact of the disease, which in the last quarter century has challenged and defeated both the scientific community and the public health field around the world.
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spelling Characterization and speculations on the urbanization of visceral leishmaniasis in BrazilVisceral LeishmaniasisUrbanizationVaccinesThe available hypotheses or explanations for the urbanization of American visceral leishmaniasis are insufficient. An alternative hypothesis is that changes in the ecology and biology of the vector, Lutzomyia longipalpis, might explain all the new urban epidemiological features of the disease. To tackle the knowledge gaps in this process, certain key research areas need to be prioritized: the role of dogs in expanding transmission in cities, community trials to evaluate new insecticides, and research on the ecological and molecular determinants of Leishmania chagasi transmission. Investment of public funds should focus on the development of a human vaccine, since such a vaccine now appears to be within reach. Even small effects from a vaccine could substantially reduce the impact of the disease, which in the last quarter century has challenged and defeated both the scientific community and the public health field around the world.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2008001200027Cadernos de Saúde Pública v.24 n.12 2008reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/S0102-311X2008001200027info:eu-repo/semantics/openAccessCosta,Carlos Henrique Neryeng2008-12-09T00:00:00Zoai:scielo:S0102-311X2008001200027Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2008-12-09T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
title Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
spellingShingle Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
Costa,Carlos Henrique Nery
Visceral Leishmaniasis
Urbanization
Vaccines
title_short Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
title_full Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
title_fullStr Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
title_full_unstemmed Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
title_sort Characterization and speculations on the urbanization of visceral leishmaniasis in Brazil
author Costa,Carlos Henrique Nery
author_facet Costa,Carlos Henrique Nery
author_role author
dc.contributor.author.fl_str_mv Costa,Carlos Henrique Nery
dc.subject.por.fl_str_mv Visceral Leishmaniasis
Urbanization
Vaccines
topic Visceral Leishmaniasis
Urbanization
Vaccines
description The available hypotheses or explanations for the urbanization of American visceral leishmaniasis are insufficient. An alternative hypothesis is that changes in the ecology and biology of the vector, Lutzomyia longipalpis, might explain all the new urban epidemiological features of the disease. To tackle the knowledge gaps in this process, certain key research areas need to be prioritized: the role of dogs in expanding transmission in cities, community trials to evaluate new insecticides, and research on the ecological and molecular determinants of Leishmania chagasi transmission. Investment of public funds should focus on the development of a human vaccine, since such a vaccine now appears to be within reach. Even small effects from a vaccine could substantially reduce the impact of the disease, which in the last quarter century has challenged and defeated both the scientific community and the public health field around the world.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2008001200027
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2008001200027
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-311X2008001200027
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
dc.source.none.fl_str_mv Cadernos de Saúde Pública v.24 n.12 2008
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br
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