Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: Konstantyner,Thais Claudia Roma de Oliveira
Data de Publicação: 2013
Outros Autores: Silva,Aline Medeiros da, Tanaka,Luana Fiengo, Marques,Heloísa Helena de Sousa, Latorre,Maria do Rosário Dias de Oliveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007
Resumo: In clinical practice, recurrence of thrush is common in children living with HIV/AIDS. The aim of this study was to determine the factors associated with time spent free of oral candidiasis using survival analysis for recurrent events. A retrospective cohort study was carried out with 287 children treated between 1985 and 2009 at a reference center in the city of São Paulo, Brazil. The Prentice, Williams and Peterson model for recurrent events was used for the investigation of factors associated with the time free of oral candidiasis. The following factors were associated with the time patients were free of oral candidiasis: moderate immunodepression (HR = 2.5; p = 0.005), severe immunodepression (HR = 3.5; p < 0.001), anemia (HR = 3.3; p < 0.001), malnutrition (HR = 2.6; p = 0.004), hospitalization (HR = 2.2; p < 0.001), monotherapy (HR = 0.5; p = 0.006), dual therapy (HR = 0.3; p < 0.001) and triple therapy/highly active antiretroviral therapy (HR = 0.1; p < 0.001). The method analyzed in the present study proved useful for the investigation of recurrent events in patients living with HIV/AIDS.
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spelling Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, BrazilOral CandidiasisHIVAcquired Immunodeficiency SyndromeChildSurvival AnalysisIn clinical practice, recurrence of thrush is common in children living with HIV/AIDS. The aim of this study was to determine the factors associated with time spent free of oral candidiasis using survival analysis for recurrent events. A retrospective cohort study was carried out with 287 children treated between 1985 and 2009 at a reference center in the city of São Paulo, Brazil. The Prentice, Williams and Peterson model for recurrent events was used for the investigation of factors associated with the time free of oral candidiasis. The following factors were associated with the time patients were free of oral candidiasis: moderate immunodepression (HR = 2.5; p = 0.005), severe immunodepression (HR = 3.5; p < 0.001), anemia (HR = 3.3; p < 0.001), malnutrition (HR = 2.6; p = 0.004), hospitalization (HR = 2.2; p < 0.001), monotherapy (HR = 0.5; p = 0.006), dual therapy (HR = 0.3; p < 0.001) and triple therapy/highly active antiretroviral therapy (HR = 0.1; p < 0.001). The method analyzed in the present study proved useful for the investigation of recurrent events in patients living with HIV/AIDS.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2013-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007Cadernos de Saúde Pública v.29 n.11 2013reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311x00069213info:eu-repo/semantics/openAccessKonstantyner,Thais Claudia Roma de OliveiraSilva,Aline Medeiros daTanaka,Luana FiengoMarques,Heloísa Helena de SousaLatorre,Maria do Rosário Dias de Oliveiraeng2016-08-16T00:00:00Zoai:scielo:S0102-311X2013001100007Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2016-08-16T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
title Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
spellingShingle Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
Konstantyner,Thais Claudia Roma de Oliveira
Oral Candidiasis
HIV
Acquired Immunodeficiency Syndrome
Child
Survival Analysis
title_short Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
title_full Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
title_fullStr Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
title_full_unstemmed Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
title_sort Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
author Konstantyner,Thais Claudia Roma de Oliveira
author_facet Konstantyner,Thais Claudia Roma de Oliveira
Silva,Aline Medeiros da
Tanaka,Luana Fiengo
Marques,Heloísa Helena de Sousa
Latorre,Maria do Rosário Dias de Oliveira
author_role author
author2 Silva,Aline Medeiros da
Tanaka,Luana Fiengo
Marques,Heloísa Helena de Sousa
Latorre,Maria do Rosário Dias de Oliveira
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Konstantyner,Thais Claudia Roma de Oliveira
Silva,Aline Medeiros da
Tanaka,Luana Fiengo
Marques,Heloísa Helena de Sousa
Latorre,Maria do Rosário Dias de Oliveira
dc.subject.por.fl_str_mv Oral Candidiasis
HIV
Acquired Immunodeficiency Syndrome
Child
Survival Analysis
topic Oral Candidiasis
HIV
Acquired Immunodeficiency Syndrome
Child
Survival Analysis
description In clinical practice, recurrence of thrush is common in children living with HIV/AIDS. The aim of this study was to determine the factors associated with time spent free of oral candidiasis using survival analysis for recurrent events. A retrospective cohort study was carried out with 287 children treated between 1985 and 2009 at a reference center in the city of São Paulo, Brazil. The Prentice, Williams and Peterson model for recurrent events was used for the investigation of factors associated with the time free of oral candidiasis. The following factors were associated with the time patients were free of oral candidiasis: moderate immunodepression (HR = 2.5; p = 0.005), severe immunodepression (HR = 3.5; p < 0.001), anemia (HR = 3.3; p < 0.001), malnutrition (HR = 2.6; p = 0.004), hospitalization (HR = 2.2; p < 0.001), monotherapy (HR = 0.5; p = 0.006), dual therapy (HR = 0.3; p < 0.001) and triple therapy/highly active antiretroviral therapy (HR = 0.1; p < 0.001). The method analyzed in the present study proved useful for the investigation of recurrent events in patients living with HIV/AIDS.
publishDate 2013
dc.date.none.fl_str_mv 2013-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0102-311x00069213
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
dc.source.none.fl_str_mv Cadernos de Saúde Pública v.29 n.11 2013
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br
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