Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007 |
Resumo: | In clinical practice, recurrence of thrush is common in children living with HIV/AIDS. The aim of this study was to determine the factors associated with time spent free of oral candidiasis using survival analysis for recurrent events. A retrospective cohort study was carried out with 287 children treated between 1985 and 2009 at a reference center in the city of São Paulo, Brazil. The Prentice, Williams and Peterson model for recurrent events was used for the investigation of factors associated with the time free of oral candidiasis. The following factors were associated with the time patients were free of oral candidiasis: moderate immunodepression (HR = 2.5; p = 0.005), severe immunodepression (HR = 3.5; p < 0.001), anemia (HR = 3.3; p < 0.001), malnutrition (HR = 2.6; p = 0.004), hospitalization (HR = 2.2; p < 0.001), monotherapy (HR = 0.5; p = 0.006), dual therapy (HR = 0.3; p < 0.001) and triple therapy/highly active antiretroviral therapy (HR = 0.1; p < 0.001). The method analyzed in the present study proved useful for the investigation of recurrent events in patients living with HIV/AIDS. |
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Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, BrazilOral CandidiasisHIVAcquired Immunodeficiency SyndromeChildSurvival AnalysisIn clinical practice, recurrence of thrush is common in children living with HIV/AIDS. The aim of this study was to determine the factors associated with time spent free of oral candidiasis using survival analysis for recurrent events. A retrospective cohort study was carried out with 287 children treated between 1985 and 2009 at a reference center in the city of São Paulo, Brazil. The Prentice, Williams and Peterson model for recurrent events was used for the investigation of factors associated with the time free of oral candidiasis. The following factors were associated with the time patients were free of oral candidiasis: moderate immunodepression (HR = 2.5; p = 0.005), severe immunodepression (HR = 3.5; p < 0.001), anemia (HR = 3.3; p < 0.001), malnutrition (HR = 2.6; p = 0.004), hospitalization (HR = 2.2; p < 0.001), monotherapy (HR = 0.5; p = 0.006), dual therapy (HR = 0.3; p < 0.001) and triple therapy/highly active antiretroviral therapy (HR = 0.1; p < 0.001). The method analyzed in the present study proved useful for the investigation of recurrent events in patients living with HIV/AIDS.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2013-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007Cadernos de Saúde Pública v.29 n.11 2013reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311x00069213info:eu-repo/semantics/openAccessKonstantyner,Thais Claudia Roma de OliveiraSilva,Aline Medeiros daTanaka,Luana FiengoMarques,Heloísa Helena de SousaLatorre,Maria do Rosário Dias de Oliveiraeng2016-08-16T00:00:00Zoai:scielo:S0102-311X2013001100007Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2016-08-16T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
title |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
spellingShingle |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil Konstantyner,Thais Claudia Roma de Oliveira Oral Candidiasis HIV Acquired Immunodeficiency Syndrome Child Survival Analysis |
title_short |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
title_full |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
title_fullStr |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
title_full_unstemmed |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
title_sort |
Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil |
author |
Konstantyner,Thais Claudia Roma de Oliveira |
author_facet |
Konstantyner,Thais Claudia Roma de Oliveira Silva,Aline Medeiros da Tanaka,Luana Fiengo Marques,Heloísa Helena de Sousa Latorre,Maria do Rosário Dias de Oliveira |
author_role |
author |
author2 |
Silva,Aline Medeiros da Tanaka,Luana Fiengo Marques,Heloísa Helena de Sousa Latorre,Maria do Rosário Dias de Oliveira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Konstantyner,Thais Claudia Roma de Oliveira Silva,Aline Medeiros da Tanaka,Luana Fiengo Marques,Heloísa Helena de Sousa Latorre,Maria do Rosário Dias de Oliveira |
dc.subject.por.fl_str_mv |
Oral Candidiasis HIV Acquired Immunodeficiency Syndrome Child Survival Analysis |
topic |
Oral Candidiasis HIV Acquired Immunodeficiency Syndrome Child Survival Analysis |
description |
In clinical practice, recurrence of thrush is common in children living with HIV/AIDS. The aim of this study was to determine the factors associated with time spent free of oral candidiasis using survival analysis for recurrent events. A retrospective cohort study was carried out with 287 children treated between 1985 and 2009 at a reference center in the city of São Paulo, Brazil. The Prentice, Williams and Peterson model for recurrent events was used for the investigation of factors associated with the time free of oral candidiasis. The following factors were associated with the time patients were free of oral candidiasis: moderate immunodepression (HR = 2.5; p = 0.005), severe immunodepression (HR = 3.5; p < 0.001), anemia (HR = 3.3; p < 0.001), malnutrition (HR = 2.6; p = 0.004), hospitalization (HR = 2.2; p < 0.001), monotherapy (HR = 0.5; p = 0.006), dual therapy (HR = 0.3; p < 0.001) and triple therapy/highly active antiretroviral therapy (HR = 0.1; p < 0.001). The method analyzed in the present study proved useful for the investigation of recurrent events in patients living with HIV/AIDS. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001100007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0102-311x00069213 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.29 n.11 2013 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115734160539648 |