Molecular epidemiology of dengue viruses in Brazil

Detalhes bibliográficos
Autor(a) principal: Nogueira, Rita Maria Ribeiro
Data de Publicação: 2000
Outros Autores: Miagostovich, Marize Pereira, Schatzmayr, Hermann Gonçalves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329
Resumo: Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.
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spelling Molecular epidemiology of dengue viruses in BrazilDengue VirusesDengueMolecular EpidemiologyDengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.Os vírus dengue (DEN) apresentam propriedades antigênicas distintas que caracterizam quatro sorotipos denominados DEN-1, 2, 3 e 4. Desde a década de 70, evidências laboratoriais têm demonstrado a ocorrência de variação intratípica entre os vírus DEN; entretanto, somente com o avanço das metodologias moleculares foi possível estabelecer variantes genéticas para cada sorotipo. A identificação genotípica tem sido uma importante abordagem para determinar a origem e a dispersão de epidemias e para tentar estabelecer correlação de virulência entre as variantes dos vírus DEN. Neste trabalho, apresentamos resultados obtidos através de estudos de epidemiologia molecular realizados com amostras de vírus DEN-1 e DEN-2, que causaram epidemias no Brasil, na última década.Reports in Public HealthCadernos de Saúde Pública2000-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329Reports in Public Health; Vol. 16 No. 1 (2000): January/MarchCadernos de Saúde Pública; v. 16 n. 1 (2000): Janeiro/Março1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329/2646https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329/2647Nogueira, Rita Maria RibeiroMiagostovich, Marize PereiraSchatzmayr, Hermann Gonçalvesinfo:eu-repo/semantics/openAccess2024-03-06T15:26:23Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/1329Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:01:35.733968Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true
dc.title.none.fl_str_mv Molecular epidemiology of dengue viruses in Brazil
title Molecular epidemiology of dengue viruses in Brazil
spellingShingle Molecular epidemiology of dengue viruses in Brazil
Nogueira, Rita Maria Ribeiro
Dengue Viruses
Dengue
Molecular Epidemiology
title_short Molecular epidemiology of dengue viruses in Brazil
title_full Molecular epidemiology of dengue viruses in Brazil
title_fullStr Molecular epidemiology of dengue viruses in Brazil
title_full_unstemmed Molecular epidemiology of dengue viruses in Brazil
title_sort Molecular epidemiology of dengue viruses in Brazil
author Nogueira, Rita Maria Ribeiro
author_facet Nogueira, Rita Maria Ribeiro
Miagostovich, Marize Pereira
Schatzmayr, Hermann Gonçalves
author_role author
author2 Miagostovich, Marize Pereira
Schatzmayr, Hermann Gonçalves
author2_role author
author
dc.contributor.author.fl_str_mv Nogueira, Rita Maria Ribeiro
Miagostovich, Marize Pereira
Schatzmayr, Hermann Gonçalves
dc.subject.por.fl_str_mv Dengue Viruses
Dengue
Molecular Epidemiology
topic Dengue Viruses
Dengue
Molecular Epidemiology
description Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.
publishDate 2000
dc.date.none.fl_str_mv 2000-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329
url https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329/2646
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/1329/2647
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
application/pdf
dc.publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
dc.source.none.fl_str_mv Reports in Public Health; Vol. 16 No. 1 (2000): January/March
Cadernos de Saúde Pública; v. 16 n. 1 (2000): Janeiro/Março
1678-4464
0102-311X
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br
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