First reported outbreak of green tobacco sickness in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265 |
Resumo: | Dermal absorption of nicotine by people harvesting tobacco may cause an acute intoxication called green tobacco sickness. Although Brazil is the second largest producer of tobacco in the world, green tobacco sickness had not been reported in the country to date. We conducted a 1:1 matched case-control study among persons involved in tobacco farming to determine the occurrence of green tobacco sickness in the northeast region of Brazil and to identify the risk factors involved. A case-patient was a person who received a diagnosis by health professional of acute intoxication during the study period and had a cotinine level over 10ng/mL detected by High Performance Liquid Chromatography. We identified 107 case-patients. The main signs and symptoms observed were dizziness, weakness, vomit, nausea and headache. Independent risk factors identified were being male, a non smoker and having worked in the harvest of tobacco leaves. Case-patients had higher median urinary cotinine levels than controls (p < 0.05). Epidemiological and laboratory data indicate for the first time the occurrence of green tobacco sickness in Brazil. |
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First reported outbreak of green tobacco sickness in BrazilTobaccoNicotineOccupational DiseasesAgricultureDermal absorption of nicotine by people harvesting tobacco may cause an acute intoxication called green tobacco sickness. Although Brazil is the second largest producer of tobacco in the world, green tobacco sickness had not been reported in the country to date. We conducted a 1:1 matched case-control study among persons involved in tobacco farming to determine the occurrence of green tobacco sickness in the northeast region of Brazil and to identify the risk factors involved. A case-patient was a person who received a diagnosis by health professional of acute intoxication during the study period and had a cotinine level over 10ng/mL detected by High Performance Liquid Chromatography. We identified 107 case-patients. The main signs and symptoms observed were dizziness, weakness, vomit, nausea and headache. Independent risk factors identified were being male, a non smoker and having worked in the harvest of tobacco leaves. Case-patients had higher median urinary cotinine levels than controls (p < 0.05). Epidemiological and laboratory data indicate for the first time the occurrence of green tobacco sickness in Brazil.A absorção dérmica da nicotina por agricultores que trabalham com o cultivo do tabaco provoca uma intoxicação aguda denominada doença da folha verde do tabaco. Apesar de o Brasil ser o segundo produtor mundial de tabaco, a doença da folha verde do tabaco ainda não havia sido relatada no país. Conduzimos um estudo de caso-controle pareado (1:1) entre pessoas envolvidas na cultura do tabaco para determinar a ocorrência de doença da folha verde do tabaco na Região Nordeste do Brasil e identificar fatores de risco. Um paciente-caso foi a pessoa que no período de estudo foi diagnosticada de intoxicação aguda por profissionais de saúde e teve nível de cotinina acima de 10ng/mL pela Cromatografia Líquida de Alta Eficiência. Identificamos 107 pacientes-caso. Principais sinais e sintomas observados foram tontura, fraqueza, vômito, náusea e cefaléia. Foram associados ao adoecimento ser do sexo masculino, não-fumantes e ter trabalhado na fase da colheita do tabaco. A mediana de cotinina urinária entre os pacientes-caso foi maior que os controles. Os dados epidemiológicos e laboratoriais confirmaram pela primeira vez a doença da folha verde do tabaco no Brasil.Reports in Public HealthCadernos de Saúde Pública2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265Reports in Public Health; Vol. 26 No. 12 (2010): DecemberCadernos de Saúde Pública; v. 26 n. 12 (2010): Dezembro1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265/8679https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265/8680Oliveira, Patricia Pereira Vasconcelos deSihler, Camila BrederodeMoura, Lenildo deMalta, Deborah CarvalhoTorres, Maria Célia de AlbuquerqueLima, Sandra Márcia da Costa PereiraLima, Ana Lucia Alves deLeite, Carlos EduardoCosta-e-Silva, Vera Luiza daSobel, JeremyLanzieri, Tatiana Mirandainfo:eu-repo/semantics/openAccess2024-03-06T15:28:04Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/4265Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:04:55.570759Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true |
dc.title.none.fl_str_mv |
First reported outbreak of green tobacco sickness in Brazil |
title |
First reported outbreak of green tobacco sickness in Brazil |
spellingShingle |
First reported outbreak of green tobacco sickness in Brazil Oliveira, Patricia Pereira Vasconcelos de Tobacco Nicotine Occupational Diseases Agriculture |
title_short |
First reported outbreak of green tobacco sickness in Brazil |
title_full |
First reported outbreak of green tobacco sickness in Brazil |
title_fullStr |
First reported outbreak of green tobacco sickness in Brazil |
title_full_unstemmed |
First reported outbreak of green tobacco sickness in Brazil |
title_sort |
First reported outbreak of green tobacco sickness in Brazil |
author |
Oliveira, Patricia Pereira Vasconcelos de |
author_facet |
Oliveira, Patricia Pereira Vasconcelos de Sihler, Camila Brederode Moura, Lenildo de Malta, Deborah Carvalho Torres, Maria Célia de Albuquerque Lima, Sandra Márcia da Costa Pereira Lima, Ana Lucia Alves de Leite, Carlos Eduardo Costa-e-Silva, Vera Luiza da Sobel, Jeremy Lanzieri, Tatiana Miranda |
author_role |
author |
author2 |
Sihler, Camila Brederode Moura, Lenildo de Malta, Deborah Carvalho Torres, Maria Célia de Albuquerque Lima, Sandra Márcia da Costa Pereira Lima, Ana Lucia Alves de Leite, Carlos Eduardo Costa-e-Silva, Vera Luiza da Sobel, Jeremy Lanzieri, Tatiana Miranda |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Patricia Pereira Vasconcelos de Sihler, Camila Brederode Moura, Lenildo de Malta, Deborah Carvalho Torres, Maria Célia de Albuquerque Lima, Sandra Márcia da Costa Pereira Lima, Ana Lucia Alves de Leite, Carlos Eduardo Costa-e-Silva, Vera Luiza da Sobel, Jeremy Lanzieri, Tatiana Miranda |
dc.subject.por.fl_str_mv |
Tobacco Nicotine Occupational Diseases Agriculture |
topic |
Tobacco Nicotine Occupational Diseases Agriculture |
description |
Dermal absorption of nicotine by people harvesting tobacco may cause an acute intoxication called green tobacco sickness. Although Brazil is the second largest producer of tobacco in the world, green tobacco sickness had not been reported in the country to date. We conducted a 1:1 matched case-control study among persons involved in tobacco farming to determine the occurrence of green tobacco sickness in the northeast region of Brazil and to identify the risk factors involved. A case-patient was a person who received a diagnosis by health professional of acute intoxication during the study period and had a cotinine level over 10ng/mL detected by High Performance Liquid Chromatography. We identified 107 case-patients. The main signs and symptoms observed were dizziness, weakness, vomit, nausea and headache. Independent risk factors identified were being male, a non smoker and having worked in the harvest of tobacco leaves. Case-patients had higher median urinary cotinine levels than controls (p < 0.05). Epidemiological and laboratory data indicate for the first time the occurrence of green tobacco sickness in Brazil. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265 |
url |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265/8679 https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4265/8680 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html application/pdf |
dc.publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
dc.source.none.fl_str_mv |
Reports in Public Health; Vol. 26 No. 12 (2010): December Cadernos de Saúde Pública; v. 26 n. 12 (2010): Dezembro 1678-4464 0102-311X reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
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1798943367024869376 |