Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience

Detalhes bibliográficos
Autor(a) principal: Luna Rodrigues Freitas-Silva
Data de Publicação: 2016
Outros Autores: Francisco Ortega
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Cadernos de Saúde Pública
Texto Completo: https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149
Resumo: Understanding the processes involved in the development of mental disorders has proven challenging ever since psychiatry was founded as a field. Neuroscience has provided new expectations that an explanation will be found for the development of mental disorders based on biological functioning alone. However, such a goal has not been that easy to achieve, and new hypotheses have begun to appear in neuroscience research. In this article we identify epigenetics, neurodevelopment, and plasticity as the principal avenues for a new understanding of the biology of mental phenomena. Genetic complexity, the environment's formative role, and variations in vulnerability involve important changes in the principal hypotheses on biological determination of mental disorders, suggesting a reconfiguration of the limits between the "social" and the "biological" in neuroscience research.
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spelling Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscienceA determinação biológica dos transtornos mentais: uma discussão a partir de teses neurocientíficas recentesBiological PsychiatryNeurosciencesMental HealthPsiquiatria BiológicaNeurociênciasSaúde MentalUnderstanding the processes involved in the development of mental disorders has proven challenging ever since psychiatry was founded as a field. Neuroscience has provided new expectations that an explanation will be found for the development of mental disorders based on biological functioning alone. However, such a goal has not been that easy to achieve, and new hypotheses have begun to appear in neuroscience research. In this article we identify epigenetics, neurodevelopment, and plasticity as the principal avenues for a new understanding of the biology of mental phenomena. Genetic complexity, the environment's formative role, and variations in vulnerability involve important changes in the principal hypotheses on biological determination of mental disorders, suggesting a reconfiguration of the limits between the "social" and the "biological" in neuroscience research.La comprensión de los procesos de formación de los trastornos mentales ha representado un desafio desde que nació el campo de la psiquiatria. El desarrollo de las neurociencias proporcionó un nuevo aliento a la expectativa de encontrar, estrictamente en el funcionamiento biológico, la explicación para el surgimiento de los trastornos mentales. No obstante, tal objetivo no se alcanza con la esperada facilidad, de modo que nuevas hipótesis comienzan a destacarse en las investigaciones neurocientíficas. En este artículo, identificamos las nociones de epigenética, neurodesarrollo y plasticidad como los principales indicativos de un nuevo modo de comprender la biología de los fenómenos mentales. La complejidad genética, el papel formativo del ambiente y las variaciones que caracterizan la vulnerabilidad implican importantes modificaciones en las principales tesis sobre la determinación biológica de los trastornos mentales, sugiriendo una reconfiguración de los límites entre lo "social" y lo "biológico" en las investigaciones en neurociencias.A compreensão dos processos de formação dos transtornos mentais vem se mostrando desafiadora desde a fundação do campo psiquiátrico. O desenvolvimento das neurociências proporcionou novo fôlego à expectativa de encontrar estritamente no funcionamento biológico a explicação para o surgimento dos transtornos mentais. No entanto, tal objetivo não vem sendo alcançado com a esperada facilidade, de modo que novas hipóteses começam a se destacar nas pesquisas neurocientíficas. Neste artigo, identificamos as noções de epigenética, neurodesenvolvimento e plasticidade como os principais indicativos de um novo modo de compreender a biologia dos fenômenos mentais. A complexidade genética, o papel formativo do ambiente e as variações que caracterizam a vulnerabilidade implicam importantes modificações nas principais teses sobre a determinação biológica dos transtornos mentais, sugerindo uma reconfiguração dos limites entre o "social" e o "biológico" nas pesquisas em neurociências.Reports in Public HealthCadernos de Saúde Pública2016-08-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmltext/htmlapplication/pdfapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149Reports in Public Health; Vol. 32 No. 8 (2016): AugustCadernos de Saúde Pública; v. 32 n. 8 (2016): Agosto1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZengporhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12988https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12989https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12990https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12991Luna Rodrigues Freitas-SilvaFrancisco Ortegainfo:eu-repo/semantics/openAccess2024-03-06T15:29:09Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/6149Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:07:01.494694Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true
dc.title.none.fl_str_mv Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
A determinação biológica dos transtornos mentais: uma discussão a partir de teses neurocientíficas recentes
title Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
spellingShingle Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
Luna Rodrigues Freitas-Silva
Biological Psychiatry
Neurosciences
Mental Health
Psiquiatria Biológica
Neurociências
Saúde Mental
title_short Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
title_full Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
title_fullStr Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
title_full_unstemmed Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
title_sort Biological determination of mental disorders: a discussion based on recent hypotheses from neuroscience
author Luna Rodrigues Freitas-Silva
author_facet Luna Rodrigues Freitas-Silva
Francisco Ortega
author_role author
author2 Francisco Ortega
author2_role author
dc.contributor.author.fl_str_mv Luna Rodrigues Freitas-Silva
Francisco Ortega
dc.subject.por.fl_str_mv Biological Psychiatry
Neurosciences
Mental Health
Psiquiatria Biológica
Neurociências
Saúde Mental
topic Biological Psychiatry
Neurosciences
Mental Health
Psiquiatria Biológica
Neurociências
Saúde Mental
description Understanding the processes involved in the development of mental disorders has proven challenging ever since psychiatry was founded as a field. Neuroscience has provided new expectations that an explanation will be found for the development of mental disorders based on biological functioning alone. However, such a goal has not been that easy to achieve, and new hypotheses have begun to appear in neuroscience research. In this article we identify epigenetics, neurodevelopment, and plasticity as the principal avenues for a new understanding of the biology of mental phenomena. Genetic complexity, the environment's formative role, and variations in vulnerability involve important changes in the principal hypotheses on biological determination of mental disorders, suggesting a reconfiguration of the limits between the "social" and the "biological" in neuroscience research.
publishDate 2016
dc.date.none.fl_str_mv 2016-08-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149
url https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12988
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12989
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12990
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/6149/12991
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
text/html
application/pdf
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dc.publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
dc.source.none.fl_str_mv Reports in Public Health; Vol. 32 No. 8 (2016): August
Cadernos de Saúde Pública; v. 32 n. 8 (2016): Agosto
1678-4464
0102-311X
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
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