Compliance with and response to hepatitis B vaccination in remaining quilombo communities in Central Brazil

• Autor(a) principal: Motta-Castro,Ana Rita C.
• Data de Publicação: 2009
• Outros Autores: Gomes,Selma A., Yoshida,Clara F. T., Miguel,Juliana C., Teles,Sheila A., Martins,Regina M. B.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Cadernos de Saúde Pública
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2009000400004
• topic: Hepatitis B Virus; Hepatitis B Vaccines; African Descendants

Compliance with and responses to the hepatitis B vaccine were evaluated in remaining quilombo communities in Central Brazil. A total of 708 individuals who were susceptible to hepatitis B virus infection were invited to participate in the hepatitis B vaccination program in eight communities. Although 567 (80%) individuals received the first dose, only 198 (28%) complied with the full vaccination scheme. Of 148 subjects who agreed to be tested for anti-HBs, 123 (83.1%; 95%CI: 75.9-88.6) responded to the vaccine. A geometric mean titer of 512mIU/mL (95%CI: 342.5-765.3) was found. Male sex and older age were independently associated with non-response. Additional health education programs and alternative hepatitis B vaccine schedules are needed to improve the vaccination coverage in these communities in Central Brazil.