Organochlorine exposure and breast cancer risk in Colombian women
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X1998000700013 |
Resumo: | An epidemiological study was performed in Santafé de Bogotá, Colombia, with a total of 306 women enrolled, including 153 incident BC cases and 153 age-matched controls. The objective of this study was to evaluate the association between BC risk and serum dichlorodiphenyl-dichloroethene (DDE) levels. Sociodemographic and reproductive data, diet, and past exposure to pesticides were obtained through a structured questionnaire. Chemical analysis of samples was performed by high resolution gas chromatography-ECD. Likelihood of developing BC by exposure to these substances was evaluated through odds ratios (OR) adjusted for: first-child breast-feeding, family BC history, body mass index (BMI), parity, and menopausal status. Data analysis was performed by conditional logistic regression techniques. Adjusted OR for exposure to serum DDE and BC suggests an increase risk of BC in the higher category of DDE exposure (OR = 1.95; CI 1.10-3.52). The test for trend was not statistically significant (p = 0.09). We confirm that serum DDE levels bear a positive association to risk of BC and could support the association between risk of BC and burden of DDE exposure. |
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Organochlorine exposure and breast cancer risk in Colombian womenBreast NeoplasmsEnvironmental ExposurePesticide ExposureLogistic RegressionCase-Control StudiesAn epidemiological study was performed in Santafé de Bogotá, Colombia, with a total of 306 women enrolled, including 153 incident BC cases and 153 age-matched controls. The objective of this study was to evaluate the association between BC risk and serum dichlorodiphenyl-dichloroethene (DDE) levels. Sociodemographic and reproductive data, diet, and past exposure to pesticides were obtained through a structured questionnaire. Chemical analysis of samples was performed by high resolution gas chromatography-ECD. Likelihood of developing BC by exposure to these substances was evaluated through odds ratios (OR) adjusted for: first-child breast-feeding, family BC history, body mass index (BMI), parity, and menopausal status. Data analysis was performed by conditional logistic regression techniques. Adjusted OR for exposure to serum DDE and BC suggests an increase risk of BC in the higher category of DDE exposure (OR = 1.95; CI 1.10-3.52). The test for trend was not statistically significant (p = 0.09). We confirm that serum DDE levels bear a positive association to risk of BC and could support the association between risk of BC and burden of DDE exposure.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz1998-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X1998000700013Cadernos de Saúde Pública v.14 suppl.3 1998reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/S0102-311X1998000700013info:eu-repo/semantics/openAccessOlaya-Contreras,P.Rodríguez-Villamil,J.Posso-Valencia,H. J.Cortez,J. E.eng2006-08-30T00:00:00Zoai:scielo:S0102-311X1998000700013Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2006-08-30T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Organochlorine exposure and breast cancer risk in Colombian women |
title |
Organochlorine exposure and breast cancer risk in Colombian women |
spellingShingle |
Organochlorine exposure and breast cancer risk in Colombian women Olaya-Contreras,P. Breast Neoplasms Environmental Exposure Pesticide Exposure Logistic Regression Case-Control Studies |
title_short |
Organochlorine exposure and breast cancer risk in Colombian women |
title_full |
Organochlorine exposure and breast cancer risk in Colombian women |
title_fullStr |
Organochlorine exposure and breast cancer risk in Colombian women |
title_full_unstemmed |
Organochlorine exposure and breast cancer risk in Colombian women |
title_sort |
Organochlorine exposure and breast cancer risk in Colombian women |
author |
Olaya-Contreras,P. |
author_facet |
Olaya-Contreras,P. Rodríguez-Villamil,J. Posso-Valencia,H. J. Cortez,J. E. |
author_role |
author |
author2 |
Rodríguez-Villamil,J. Posso-Valencia,H. J. Cortez,J. E. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Olaya-Contreras,P. Rodríguez-Villamil,J. Posso-Valencia,H. J. Cortez,J. E. |
dc.subject.por.fl_str_mv |
Breast Neoplasms Environmental Exposure Pesticide Exposure Logistic Regression Case-Control Studies |
topic |
Breast Neoplasms Environmental Exposure Pesticide Exposure Logistic Regression Case-Control Studies |
description |
An epidemiological study was performed in Santafé de Bogotá, Colombia, with a total of 306 women enrolled, including 153 incident BC cases and 153 age-matched controls. The objective of this study was to evaluate the association between BC risk and serum dichlorodiphenyl-dichloroethene (DDE) levels. Sociodemographic and reproductive data, diet, and past exposure to pesticides were obtained through a structured questionnaire. Chemical analysis of samples was performed by high resolution gas chromatography-ECD. Likelihood of developing BC by exposure to these substances was evaluated through odds ratios (OR) adjusted for: first-child breast-feeding, family BC history, body mass index (BMI), parity, and menopausal status. Data analysis was performed by conditional logistic regression techniques. Adjusted OR for exposure to serum DDE and BC suggests an increase risk of BC in the higher category of DDE exposure (OR = 1.95; CI 1.10-3.52). The test for trend was not statistically significant (p = 0.09). We confirm that serum DDE levels bear a positive association to risk of BC and could support the association between risk of BC and burden of DDE exposure. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X1998000700013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X1998000700013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-311X1998000700013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.14 suppl.3 1998 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115718884884480 |