Impact of the Haemophilus influenzae type b vaccination program on HIB meningitis in Brazil

• Autor(a) principal: Miranzi,Sybelle de Souza Castro
• Data de Publicação: 2007
• Outros Autores: Moraes,Suzana Alves de, Freitas,Isabel Cristina Martins de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Cadernos de Saúde Pública
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2007000700021
• topic: Haemophilus influenzae; Bacterial Meningitis; Vaccination; Time Series Studies

This study aimed to evaluate the impact of vaccination against Haemophilus influenzae type b (HIB) in Brazil on the morbidity, mortality, and case fatality of HIB meningitis, using the Ministry of Health database and population data from the Brazilian Institute of Geography and Statistics (Instituto Brasileiro de Geografia e Estatística - IBGE). Impact was evaluated through a time series analysis (1983-2002), using regression forecasting (RF) by dividing the time series into two periods: (a) historical (1983-1998) and (b) validation (1999-2002). Impact of the vaccination was positive, although more significant for incidence and mortality than for case fatality rates.