The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design

Detalhes bibliográficos
Autor(a) principal: Lucas Silva
Data de Publicação: 2020
Outros Autores: Dalson Figueiredo Filho, Antônio Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335
Resumo: In response to the COVID-19 pandemic, governments worldwide have implemented social distancing policies with different levels of both enforcement and compliance. We conducted an interrupted time series analysis to estimate the impact of lockdowns on reducing the number of cases and deaths due to COVID-19 in Brazil. Official daily data was collected for four city capitals before and after their respective policies interventions based on a 14 days observation window. We estimated a segmented linear regression to evaluate the effectiveness of lockdown measures on COVID-19 incidence and mortality. The initial number of new cases and new deaths had a positive trend prior to policy change. After lockdown, a statistically significant decrease in new confirmed cases was found in all state capitals. We also found evidence that lockdown measures were likely to reverse the trend of new daily deaths due to COVID-19. In São Luís, we observed a reduction of 37.85% while in Fortaleza the decrease was 33.4% on the average difference in daily deaths if the lockdown had not been implemented. Similarly, the intervention diminished mortality in Recife by 21.76% and Belém by 16.77%. Social distancing policies can be useful tools in flattening the epidemic curve.
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spelling The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series designSARS-CoV-2COVID-19Social DistanceInterrupted Time SeriesIn response to the COVID-19 pandemic, governments worldwide have implemented social distancing policies with different levels of both enforcement and compliance. We conducted an interrupted time series analysis to estimate the impact of lockdowns on reducing the number of cases and deaths due to COVID-19 in Brazil. Official daily data was collected for four city capitals before and after their respective policies interventions based on a 14 days observation window. We estimated a segmented linear regression to evaluate the effectiveness of lockdown measures on COVID-19 incidence and mortality. The initial number of new cases and new deaths had a positive trend prior to policy change. After lockdown, a statistically significant decrease in new confirmed cases was found in all state capitals. We also found evidence that lockdown measures were likely to reverse the trend of new daily deaths due to COVID-19. In São Luís, we observed a reduction of 37.85% while in Fortaleza the decrease was 33.4% on the average difference in daily deaths if the lockdown had not been implemented. Similarly, the intervention diminished mortality in Recife by 21.76% and Belém by 16.77%. Social distancing policies can be useful tools in flattening the epidemic curve.En respuesta a la pandemia de COVID-19, muchos gobiernos en todo el mundo han implementado las políticas de distanciamiento social con diferentes niveles, tanto en lo que se refiere a la observancia, como al cumplimiento. Realizamos un análisis de serie temporal interrumpida para estimar el impacto de los confinamientos en reducir el número de casos y muertes, debidos a la COVID-19 en Brasil. Los datos oficiales diarios fueron recogidos de cuatro capitales antes y después de sus respectivas políticas de intervención, basadas en el mantenimiento de 14 días de observación de autoconfinamiento. Estimamos una regresión lineal segmentada para evaluar la efectividad de las medidas de confinamiento en la incidencia de COVID-19 y la mortalidad. El número inicial de nuevos casos y nuevas muertes tuvo una tendencia positiva previa al cambio de política. Tras el confinamiento, se presentó una disminución estadísticamente significativa de nuevos casos confirmados, que fueron encontrados en todas las capitales de estado. De igual modo, encontramos evidencias de que las medidas de confinamiento probablemente revirtieron la tendencia de nuevas muertes diarias debidas al COVID-19. En São Luís, observamos la reducción de un 37,85%, mientras en Fortaleza la disminución fue de un 33,4% en la diferencia media en muertes diarias, si no se hubiera implementado el confinamiento. Igualmente, la intervención redujo la mortalidad en Recife en un 21,76% y Belém tuvo un 16,77%. Las políticas de distanciamiento social pueden ser herramientas útiles en el aplanamiento de la curva epidémica.Em resposta à pandemia da COVID-19, muitos governos no mundo adotaram políticas de distanciamento social, com diferentes níveis de implementação e adesão. Realizamos uma análise de séries temporárias interrompidas para estimar o impacto dos lockdowns na redução do número de casos e óbitos por COVID-19 no Brasil. Os dados diários oficiais foram coletados para quatro capitais estaduais, antes e depois das respectivas intervenções políticas, com base em uma janela de 14 dias de observação. Estimamos uma regressão linear segmentada para avaliar a efetividade das medidas de lockdown sobre a incidência e mortalidade de COVID-19. O número inicial de novos casos e óbitos mostrou uma tendência positiva antes da mudança política. Depois do lockdown, foi observada uma queda estatisticamente significativa em novos casos confirmados, em todas as capitais. De maneira semelhante, as evidências mostraram que medidas de distanciamento revertiam a tendência de novos óbitos diários pela COVID-19. Em São Luís, observamos uma redução de 37,85%, enquanto em Fortaleza a queda foi de 33,4% na diferença média em óbitos diários, comparado com uma eventual não implementação de lockdown. Além disso, a intervenção diminuiu a mortalidade em Recife em 21,76%, e em Belém em 16,77%. As políticas de distanciamento social podem ser ferramentas úteis no achatamento da curva epidêmica.Reports in Public HealthCadernos de Saúde Pública2020-10-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335Reports in Public Health; Vol. 36 No. 10 (2020): OctoberCadernos de Saúde Pública; v. 36 n. 10 (2020): Outubro1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335/16132https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335/16133Lucas SilvaDalson Figueiredo FilhoAntônio Fernandesinfo:eu-repo/semantics/openAccess2024-03-06T15:29:53Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/7335Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:08:26.005022Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true
dc.title.none.fl_str_mv The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
title The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
spellingShingle The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
Lucas Silva
SARS-CoV-2
COVID-19
Social Distance
Interrupted Time Series
title_short The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
title_full The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
title_fullStr The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
title_full_unstemmed The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
title_sort The effect of lockdown on the COVID-19 epidemic in Brazil: evidence from an interrupted time series design
author Lucas Silva
author_facet Lucas Silva
Dalson Figueiredo Filho
Antônio Fernandes
author_role author
author2 Dalson Figueiredo Filho
Antônio Fernandes
author2_role author
author
dc.contributor.author.fl_str_mv Lucas Silva
Dalson Figueiredo Filho
Antônio Fernandes
dc.subject.por.fl_str_mv SARS-CoV-2
COVID-19
Social Distance
Interrupted Time Series
topic SARS-CoV-2
COVID-19
Social Distance
Interrupted Time Series
description In response to the COVID-19 pandemic, governments worldwide have implemented social distancing policies with different levels of both enforcement and compliance. We conducted an interrupted time series analysis to estimate the impact of lockdowns on reducing the number of cases and deaths due to COVID-19 in Brazil. Official daily data was collected for four city capitals before and after their respective policies interventions based on a 14 days observation window. We estimated a segmented linear regression to evaluate the effectiveness of lockdown measures on COVID-19 incidence and mortality. The initial number of new cases and new deaths had a positive trend prior to policy change. After lockdown, a statistically significant decrease in new confirmed cases was found in all state capitals. We also found evidence that lockdown measures were likely to reverse the trend of new daily deaths due to COVID-19. In São Luís, we observed a reduction of 37.85% while in Fortaleza the decrease was 33.4% on the average difference in daily deaths if the lockdown had not been implemented. Similarly, the intervention diminished mortality in Recife by 21.76% and Belém by 16.77%. Social distancing policies can be useful tools in flattening the epidemic curve.
publishDate 2020
dc.date.none.fl_str_mv 2020-10-19
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335
url https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335/16132
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/7335/16133
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
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dc.publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
publisher.none.fl_str_mv Reports in Public Health
Cadernos de Saúde Pública
dc.source.none.fl_str_mv Reports in Public Health; Vol. 36 No. 10 (2020): October
Cadernos de Saúde Pública; v. 36 n. 10 (2020): Outubro
1678-4464
0102-311X
reponame:Cadernos de Saúde Pública
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reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br
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