Evaluation of adverse drug reactions notifications at a public hospital in Minas Gerais

• Autor(a) principal: de Lima, Thaís Cristina
• Data de Publicação: 2021
• Outros Autores: Portes de Almeida, Priscila, Gontijo de Oliveira Rezende, Dayana
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Vigilância Sanitária em Debate
• Texto Completo: https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1924
• topic: Pharmacovigilance; Notifcation; Adverse Drug Reactions; Farmacovigilância; Notifcação; Reações Adversas a Medicamentos

Introduction: Adverse drug reactions (ADR’s) are considered a serious public health problem, being responsible for the increase in morbidity and mortality and health costs. Objective: To know the occurrence profile and describe the characteristics of the cases of ADRs notified in a sentinel hospital in Minas Gerais. Method: Observational, descriptive and cross-sectional study, which used as a source the spreadsheet of suspected ADR’s reports from the hospital's risk management from January 2015 to December 2019. Results: 255 notifications were analyzed, the majority coming from active search (69.4%), involving 269 medications and 328 episodes of ADR’s. The sector with the highest number of notifications was the Medical Clinic (43.9%). The age range of the most affected patients was between 19-59 years (54.5%), predominantly male (50.6%) and white (54.1%). Most of the ADR's were manifested through disorders in the integumentary system (36.3%), with mild severity (63.9%), mainly due to the use of systemic anti-infectives (44.6%). Conclusion: It is concluded that the notifications of ADR’s are recurrent in the hospital and their knowledge allows to outline their clinical profile, helping to prevent them and contributing to greater patient safety.