Diabetes mellitus, obesity and bad lifestyle habits: their relationship with COVID-19

• Autor(a) principal: Monteiro, Amanda Rainha
• Data de Publicação: 2020
• Outros Autores: Barros, Ludmila Alves dos Santos, Albernaz, Pedro Cardoso Siqueira, Vieira, Victor Barcellos de Azeredo, Barroso, Victoria Dias de Miranda Paula, Rodrigues, Marta Cristina da Cunha
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://www.fmc.br/ojs/index.php/RCFMC/article/view/377
• topic: Coronavírus; SARS-CoV-2; metabolismo; inflamação; Coronavirus; SARS-CoV-2; metabolism; inflammation

In 2019, SARS-CoV-2 virus was discovered, causing a global health crisis. The 2020 pandemic, caused by the so-called "Coronavirus disease 2019" or COVID-19, spread rapidly around the world, impacting the global population and especially some groups at risk, such as patients with cardiovascular diseases, obesity and diabetes. This study aims to analyze and report the relationships between COVID-19 and patients with metabolic disorders such as diabetes mellitus or obesity, and also to expose how life habits can interfere with SARS-CoV-2 infection. This is a literature review on the main consensus and studies about COVID-19. It is known that the virus initiates the process of infection in the upper respiratory tract to begin the cycle of viral replication. Diabetes mellitus is considered a risk factor of high severity and mortality, since hyperglycemia alters the immune response of the subject, resulting in higher risks of infections. Also, obese people have a significant risk due to high production of pro-inflammatory cytokines and T-cell functional changes that cause a weakened immune response to contain the infection. It is essential to invest in disease prevention measures, such as the practice of physical activities and changes to good eating habits in order to improve life quality and to have an effective immune response especially in the pandemic context.