NEUROLEPTIC MALIGNANT SYNDROME IN PATIENT IN OLANZAPINE USE - CASE REPORT

• Autor(a) principal: Mendonça, Sandro Bichara
• Data de Publicação: 2016
• Outros Autores: Mendonça, Gabriel Soares, Quitete, Marcela, Range, Carolina Cassiano, Bravin, Débora Moreira
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://www.fmc.br/ojs/index.php/RCFMC/article/view/14
• topic: Síndrome neuroléptica maligna; olanzapina; clínica; diagnóstico; tratamento; neuroleptic malignant syndrome; olanzapine; clinic; diagnosis; treatment.

Introduction: Neuroleptic Malignant Syndrome (NMS) is a major complication of the use of antipsychotics, relatively rare, but potentially fatal, and can lead to death in 10-20 % of cases.1-5. This syndrome is characterized by severe muscle stiffness development and hyperthermia associated with at least two other symptoms: Diaphoresis, dysphagia, tremor, incontinence, confusion / coma, mutism, tachycardia / tachypnea, high or unstable blood pressure, leukocytosis and CPK elevation6 . Objective: To report a case of a diabetic and hypertensive patients in psychiatric care for bipolar affective disorder that developed Neuroleptic Malignant Syndrome by the use of atypical antipsychotics: olanzapine, aiming suggest clinical procedures that can improve the diagnostic accuracy of Neuroleptic Malignant Syndrome and, therefore, therapeutic efficacy. Method: Information was obtained through medical record review, photographic documentation of diagnostic methods to which the patient underwent and literature review in specialized sources: books, magazines, articles available on Internet sites (Scielo, Bireme, Pubmed, Journal of Psychiatry, other) using as keywords: neuroleptic malignant syndrome; olanzapine clinical; diagnostics; treatment. Conclusion: Concluded to be essential for an excellent medical practice, with significant therapeutic and prognostic efficacy, the initial exercise, in all patients, of anamnesis and meticulous physical examination, followed by targeted clinical exams and systematically analyzed, aiming identification early lifethreatening medical conditions and their early and effective therapeutic management.