Carbamazepine hypersensitivity reaction associated with severe clinical condition: Case Report

• Autor(a) principal: Rodrigues, Maurício Assis
• Data de Publicação: 2016
• Outros Autores: Santos Filho, Fabiano de Souza, Rocha Junior, Oscar Lara, Ferreira, Carlos Eduardo Faria
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://www.fmc.br/ojs/index.php/RCFMC/article/view/13
• topic: Carbamazepina; Efeitos Colaterais; Reações Adversas a Medicamentos; Anticonvulsivantes; Carbamazepine; Drug-Related Side Effects; Adverse Reactions; Anticonvulsants

ntroduction: Carbamazepine is an aromatic anticonvulsant widely used for the treatment of seizures and bipolar disorder, and one of the drugs involved in hypersensitivity reactions. Objective: Report a case of carbamazepine hypersensitivity. Case Report: Male, white, 49, was admitted to the medical clinic presenting episodes of fever and rash skin rash on the body, face and limbs. It has a history of psychiatric treatment, making regular use of psychotherapeutic drugs as Rivotril, pimozide and carbamazepine. After discussing the case, the hospital’s multidisciplinary team discussed the possibility of hypersensitivity to carbamazepine and requested the suspension of the drug. After this conduct in a few days progressed with total regression of symptoms. Conclusions: Hypersensitivity reactions to anticonvulsants like carbamazepine represent a public health problem. Early identification of these reactions minimizes the suffering of the patient, reduces public spending on admissions and promotes better access to healthcare for the population in general.