Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review

Detalhes bibliográficos
Autor(a) principal: Lima Soares Chagas, Alany
Data de Publicação: 2023
Outros Autores: Queiroz Moura, Heloise Gabriella, Renaly Brayner de Sá, Klyvia, Duarte Nascimento, Laila Caroline, Cândida Pereira Guedes, Larissa, Gonçalves Pinheiro Moura, Priscyla, da Cruz, Tharcia Kiara
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Anais da Faculdade de Medicina de Olinda (Online)
Texto Completo: https://afmo.emnuvens.com.br/afmo/article/view/252
Resumo: Hypericum perforatum, known as St. John’s wort, is a popular medicinal plant recom mended in traditional Chinese medicine and prescribed for depression in European coun tries. However, conflicting data were observed regarding its benefits and risks. This study aimed to evaluate phytopharmaceuticals containing Hypericum perforatum extracts for anxiety and depression treatment. An integrative review was performed by searching Literatura Latino-Americana e do Caribe em Saúde (LILACS), Scientific Electronic Library Online (SciELO), and Publisher Medline (PubMed) databases and included studies in Portuguese, English, and Spanish from 2017 to 2022. Randomized clinical trials confirmed the efficacy of the Hypericum perforatum extracts compared with placebo on mild and moderately severe depression. Further randomized controlled studies demonstrated similar efficacy to conventional antidepressants for anxiety and mild to moderate depression. The study concludes the need for more studies to evaluate the efficacy of Hypericum perforatum extracts, especially concerning adverse effects, risks, and drug interactions.
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spelling Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative reviewAplicações terapêuticas do Hypericum perforatum (erva-de-são-joão) no tratamento da ansiedade e depressão: revisão integrativaAnsiedadeDepressãoMedicamento fitoterápicoHypericum perforatumAnxietyDepressionPhytopharmaceuticalsHypericum perforatumHypericum perforatum, known as St. John’s wort, is a popular medicinal plant recom mended in traditional Chinese medicine and prescribed for depression in European coun tries. However, conflicting data were observed regarding its benefits and risks. This study aimed to evaluate phytopharmaceuticals containing Hypericum perforatum extracts for anxiety and depression treatment. An integrative review was performed by searching Literatura Latino-Americana e do Caribe em Saúde (LILACS), Scientific Electronic Library Online (SciELO), and Publisher Medline (PubMed) databases and included studies in Portuguese, English, and Spanish from 2017 to 2022. Randomized clinical trials confirmed the efficacy of the Hypericum perforatum extracts compared with placebo on mild and moderately severe depression. Further randomized controlled studies demonstrated similar efficacy to conventional antidepressants for anxiety and mild to moderate depression. The study concludes the need for more studies to evaluate the efficacy of Hypericum perforatum extracts, especially concerning adverse effects, risks, and drug interactions.O Hypericum perforatum, também conhecido como erva de São João é uma planta medicinal popular recomendada pelos praticantes da medicina tradicional chinesa e amplamente prescrita para a depressão em muitos países europeus. No entanto, existem dados conflitantes sobre seus benefícios e riscos. O objetivo deste estudo foi avaliar os benefícios e riscos dos fitoterápicos contendo Hypericum perforatum. no tratamento da ansiedade e depressão. Realizou-se uma revisão integrativa a partir de artigos publicados em nas bases científicas Literatura Latino-americana e do Caribe em Saúde (LILACS), Scientific Electronic Library Online (SciELO) e Publisher Medline (PubMed) entre os anos de 2017 a 2022 nos idiomas português, inglês e espanhol. Evidências de ensaios clínicos randomizados confirmaram a eficácia dos extratos de Hypericum Perforatu. em relação ao placebo no tratamento da depressão leve a moderadamente grave. Outros estudos randomizados controlados forneceram algumas evidências de que os extratos da planta são tão eficazes quanto alguns antidepressivos convencionais na ansiedade e depressão leve a moderada. Conclui-se que há a necessidade de mais estudos para avaliar a eficácia dos extratos de Hypericum Perforatum, principalmente no que se refere aos eventos adversos, possíveis riscos e interações com outros medicamentos.Faculdade de Medicina de Olinda2023-06-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://afmo.emnuvens.com.br/afmo/article/view/25210.56102/afmo.2023.252Annals of Olinda Medical School; Vol. 1 No. 9 (2023); 55-63Anais da Faculdade de Medicina de Olinda; v. 1 n. 9 (2023); 55-632674-84872595-1734reponame:Anais da Faculdade de Medicina de Olinda (Online)instname:Faculdade de Medicina de Olinda (FMO)instacron:FMOporenghttps://afmo.emnuvens.com.br/afmo/article/view/252/138https://afmo.emnuvens.com.br/afmo/article/view/252/180Copyright (c) 2023 Alany Lima Soares Chagas, Heloise Gabriella Queiroz Moura, Klyvia Renaly Brayner de Sá, Laila Caroline Duarte Nascimento, Larissa Cândida Pereira Guedes, Priscyla Gonçalves Pinheiro Moura, Tharcia Kiara da Cruzhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLima Soares Chagas, AlanyQueiroz Moura, Heloise GabriellaRenaly Brayner de Sá, KlyviaDuarte Nascimento, Laila CarolineCândida Pereira Guedes, LarissaGonçalves Pinheiro Moura, Priscylada Cruz, Tharcia Kiara2024-04-09T22:54:45Zoai:ojs.afmo.emnuvens.com.br:article/252Revistahttps://afmo.emnuvens.com.br/afmoPUBhttps://afmo.emnuvens.com.br/afmo/oaianaisfmo@fmo.edu.br2674-84872595-1734opendoar:2024-04-09T22:54:45Anais da Faculdade de Medicina de Olinda (Online) - Faculdade de Medicina de Olinda (FMO)false
dc.title.none.fl_str_mv Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
Aplicações terapêuticas do Hypericum perforatum (erva-de-são-joão) no tratamento da ansiedade e depressão: revisão integrativa
title Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
spellingShingle Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
Lima Soares Chagas, Alany
Ansiedade
Depressão
Medicamento fitoterápico
Hypericum perforatum
Anxiety
Depression
Phytopharmaceuticals
Hypericum perforatum
title_short Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
title_full Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
title_fullStr Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
title_full_unstemmed Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
title_sort Therapeutic applications of Hypericum perforatum (St. John’s wort) for treating anxiety and depression: integrative review
author Lima Soares Chagas, Alany
author_facet Lima Soares Chagas, Alany
Queiroz Moura, Heloise Gabriella
Renaly Brayner de Sá, Klyvia
Duarte Nascimento, Laila Caroline
Cândida Pereira Guedes, Larissa
Gonçalves Pinheiro Moura, Priscyla
da Cruz, Tharcia Kiara
author_role author
author2 Queiroz Moura, Heloise Gabriella
Renaly Brayner de Sá, Klyvia
Duarte Nascimento, Laila Caroline
Cândida Pereira Guedes, Larissa
Gonçalves Pinheiro Moura, Priscyla
da Cruz, Tharcia Kiara
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lima Soares Chagas, Alany
Queiroz Moura, Heloise Gabriella
Renaly Brayner de Sá, Klyvia
Duarte Nascimento, Laila Caroline
Cândida Pereira Guedes, Larissa
Gonçalves Pinheiro Moura, Priscyla
da Cruz, Tharcia Kiara
dc.subject.por.fl_str_mv Ansiedade
Depressão
Medicamento fitoterápico
Hypericum perforatum
Anxiety
Depression
Phytopharmaceuticals
Hypericum perforatum
topic Ansiedade
Depressão
Medicamento fitoterápico
Hypericum perforatum
Anxiety
Depression
Phytopharmaceuticals
Hypericum perforatum
description Hypericum perforatum, known as St. John’s wort, is a popular medicinal plant recom mended in traditional Chinese medicine and prescribed for depression in European coun tries. However, conflicting data were observed regarding its benefits and risks. This study aimed to evaluate phytopharmaceuticals containing Hypericum perforatum extracts for anxiety and depression treatment. An integrative review was performed by searching Literatura Latino-Americana e do Caribe em Saúde (LILACS), Scientific Electronic Library Online (SciELO), and Publisher Medline (PubMed) databases and included studies in Portuguese, English, and Spanish from 2017 to 2022. Randomized clinical trials confirmed the efficacy of the Hypericum perforatum extracts compared with placebo on mild and moderately severe depression. Further randomized controlled studies demonstrated similar efficacy to conventional antidepressants for anxiety and mild to moderate depression. The study concludes the need for more studies to evaluate the efficacy of Hypericum perforatum extracts, especially concerning adverse effects, risks, and drug interactions.
publishDate 2023
dc.date.none.fl_str_mv 2023-06-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://afmo.emnuvens.com.br/afmo/article/view/252
10.56102/afmo.2023.252
url https://afmo.emnuvens.com.br/afmo/article/view/252
identifier_str_mv 10.56102/afmo.2023.252
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://afmo.emnuvens.com.br/afmo/article/view/252/138
https://afmo.emnuvens.com.br/afmo/article/view/252/180
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Faculdade de Medicina de Olinda
publisher.none.fl_str_mv Faculdade de Medicina de Olinda
dc.source.none.fl_str_mv Annals of Olinda Medical School; Vol. 1 No. 9 (2023); 55-63
Anais da Faculdade de Medicina de Olinda; v. 1 n. 9 (2023); 55-63
2674-8487
2595-1734
reponame:Anais da Faculdade de Medicina de Olinda (Online)
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reponame_str Anais da Faculdade de Medicina de Olinda (Online)
collection Anais da Faculdade de Medicina de Olinda (Online)
repository.name.fl_str_mv Anais da Faculdade de Medicina de Olinda (Online) - Faculdade de Medicina de Olinda (FMO)
repository.mail.fl_str_mv anaisfmo@fmo.edu.br
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