Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da FAMERP |
Texto Completo: | http://bdtd.famerp.br/handle/tede/394 |
Resumo: | Introduction: Lymphedema is a clinical condition in which there is an accumulation of macromolecules in the interstitial space. As a result, it promotes water retention, consequently a failure in the formation or lymph drainage. Objectives: To access the images obtained from Computed Scintigraphy Chamber through a specific protocol of Lymphoscintigraphy and associate them to epidemiological data such as gender, age, educational level, socioeconomic status and prevalence of Lymphedema. Method: Epidemiological data were evaluated in a quantitative cross-sectional study comparing the diagnostic results for Lymphedema of the lower limbs using the Lymphoscintigraphy. They were correlated with gender, age, education level, family income and prevalence among the lower limbs at Hospital de Base in the last 10 years, 2006 to 2016. All patients clinically suspected of Lymphedema of the lower limbs were included and lymphoscintigraphic examinations of the upper limbs were excluded. Descriptive data were considered, and Fisher's exact test was used to correlate these variables considering alpha error of 5%. Results: A total of 430 patients were analyzed, 320(74.42%) were female and 110 (25.58%) male patients. Their age ranged from 10 to 90 years (mean = 48 years). A total 199 (46.27%) were positive findings and 231 (53.73%) negative. Among the images analyzed as positive; female patients were the majority, 183 (91.95%); Fisher's exact test p-value <0.001. When comparing patients with the first grade of high school with patients with complete college education, it was clear that Lymphedema was more prevalent in the first grade of high school, according to Fisher's exact test, p<0.0001. Comparing the second grade of high school with the ones with college education, it was observed that Lymphedema was more prevalent in those with high school; Fisher's exact test, p<0.0001. When comparing the wage gain from one to three minimum wages per month with three to five gains, five to seven and over seven salaries, a higher prevalence of Lymphedema was observed in the group of one to three salaries in relation to the others by Fisher's exact test, p<0.0001 in all evaluations. Comparing the salary range of three to five salaries with the salary range of five to seven and over seven monthly minimum wages, greater prevalence was observed in the range of three to five minimum wages; Fisher's exact test, p<0, 0.001 in both comparisons. The right lower limb presented 65 patients (32.66%), and 87(43.71%) unilateral left limb and 7 patients (23.63%), bilaterally were found. The left side was more prevalent than the right side; Fisher's exact test, p<0.01. Conclusions: Lymphedema is a public health issue that affects mostly women from lower cultural-educational socioeconomic status. One-sided onset can occur in the limb, but bilateral occurrence is frequent and Lymphoscintigraphy is useful in defining the diagnosis in cases of doubt. |
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Godoy, Maria de Fátima GuerreiroGodoy, José Maria Pereira deIozzi-klein, AdrianaMonteiro Neto, Luis Ferreira14785450894http://lattes.cnpq.br/5432800503774985Sant'Anna, Kleber Roberto2018-01-17T11:04:30Z2017-03-08Sant'Anna, Kleber Roberto. Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores. 2017. 43 f. Dissertação (Programa de Pós-Graduação em Ciências da Saúde) - Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto.1296http://bdtd.famerp.br/handle/tede/394Introduction: Lymphedema is a clinical condition in which there is an accumulation of macromolecules in the interstitial space. As a result, it promotes water retention, consequently a failure in the formation or lymph drainage. Objectives: To access the images obtained from Computed Scintigraphy Chamber through a specific protocol of Lymphoscintigraphy and associate them to epidemiological data such as gender, age, educational level, socioeconomic status and prevalence of Lymphedema. Method: Epidemiological data were evaluated in a quantitative cross-sectional study comparing the diagnostic results for Lymphedema of the lower limbs using the Lymphoscintigraphy. They were correlated with gender, age, education level, family income and prevalence among the lower limbs at Hospital de Base in the last 10 years, 2006 to 2016. All patients clinically suspected of Lymphedema of the lower limbs were included and lymphoscintigraphic examinations of the upper limbs were excluded. Descriptive data were considered, and Fisher's exact test was used to correlate these variables considering alpha error of 5%. Results: A total of 430 patients were analyzed, 320(74.42%) were female and 110 (25.58%) male patients. Their age ranged from 10 to 90 years (mean = 48 years). A total 199 (46.27%) were positive findings and 231 (53.73%) negative. Among the images analyzed as positive; female patients were the majority, 183 (91.95%); Fisher's exact test p-value <0.001. When comparing patients with the first grade of high school with patients with complete college education, it was clear that Lymphedema was more prevalent in the first grade of high school, according to Fisher's exact test, p<0.0001. Comparing the second grade of high school with the ones with college education, it was observed that Lymphedema was more prevalent in those with high school; Fisher's exact test, p<0.0001. When comparing the wage gain from one to three minimum wages per month with three to five gains, five to seven and over seven salaries, a higher prevalence of Lymphedema was observed in the group of one to three salaries in relation to the others by Fisher's exact test, p<0.0001 in all evaluations. Comparing the salary range of three to five salaries with the salary range of five to seven and over seven monthly minimum wages, greater prevalence was observed in the range of three to five minimum wages; Fisher's exact test, p<0, 0.001 in both comparisons. The right lower limb presented 65 patients (32.66%), and 87(43.71%) unilateral left limb and 7 patients (23.63%), bilaterally were found. The left side was more prevalent than the right side; Fisher's exact test, p<0.01. Conclusions: Lymphedema is a public health issue that affects mostly women from lower cultural-educational socioeconomic status. One-sided onset can occur in the limb, but bilateral occurrence is frequent and Lymphoscintigraphy is useful in defining the diagnosis in cases of doubt.Introdução: O Linfedema é uma condição clínica na qual ocorre um acúmulo de macromoléculas no espaço intersticial. Como consequência, promove retenção hídrica tendo como causa uma falha na formação ou na drenagem da linfa. Objetivos: Avaliar as imagens obtidas em Câmara de Cintilação Computadorizada por meio do protocolo de Linfocintilografia específico e relacioná-las com dados epidemiológicos como sexo, idade, grau de escolaridade, nível socioeconômico e prevalência de Linfedema. Método: Foram avaliados em estudo transversal quantitativo, dados epidemiológicos comparando-se os resultados diagnósticos para Linfedema de membros inferiores, utilizando a Linfocintilografia. Foram correlacionados com o sexo, idade, grau de escolaridade, renda familiar e predominância entre os membros inferiores no Hospital de Base nos últimos 10 anos, 2006 a 2016. Foram inclusos todos os pacientes com suspeita clínica de Linfedema de membros inferiores e excluídos os exames Linfocintilográficos de membros superiores. Foram considerados dados descritivos e utilizado o teste exato de Fisher para correlacionar essas variáveis, considerando-se erro alfa de 5%. Resultados: Foram analisados 430 pacientes sendo que 320(74,42%) eram pacientes do sexo feminino e 110(25,58%) pacientes do sexo masculino. A idade dos pacientes variava de 10 a 90 anos (média=48 anos). Os achados positivos somavam 199(46,27%) e negativos 231(53,73%); dentre as imagens analisadas como positivas, predominavam pacientes do sexo feminino; 183(91,95%); no teste exato de Fisher valor p<0,001. Quando se comparou o primeiro grau de escolaridade do ensino médio com o segundo grau do ensino médio, ficou evidenciado que o Linfedema é mais prevalente no primeiro grau do ensino médio, de acordo com o teste exato de Fisher, valor p<0,0001. Comparando-se o primeiro grau do ensino médio com os pacientes que possuíam grau do ensino superior, detectou-se que a prevalência do Linfedema é maior no primeiro ano do ensino médio de escolaridade; teste exato de Fisher, valor p<0,0001. Comparando-se segundo grau do ensino médio de escolaridade com os do ensino superior, detectou-se que o Linfedema é mais prevalente no segundo grau do ensino médio; teste exato de Fisher, valor p<0,0001.Quando se comparou o ganho salarial de um a três salários mínimos por mês com ganhos de três a cinco, cinco a sete e acima de sete salários detectou-se uma maior prevalência do Linfedema no grupo de um a três salários em relação aos demais com teste exato de Fisher, valor p<0,0001 em todas as avaliações. Comparando-se a faixa salarial de três a cinco salários com a faixa salarial de cinco a sete e maior que sete salários mínimos mensais detectou-se maior prevalência na faixa de três a cinco salários mínimos, teste exato de Fisher, valor p<0,0001 nas duas comparações. O membro inferior direito apresentou 65 pacientes (32,66%), e 87(43,71%) achados unilaterais de membro inferior esquerdo e bilateralmente em 47 pacientes (23,63%). O lado esquerdo é mais prevalente que o lado direito; teste exato de Fisher, valor p<0,01. Conclusões: O Linfedema é um problema de saúde pública que acomete na sua maioria, as mulheres de classe socioeconômica cultural e educacional mais baixa. Ocorre uma unilateralização no acometimento do membro, porém a ocorrência bilateral é frequente e a Linfocintilografia é útil na definição do diagnóstico nos casos de dúvida.Submitted by Fabíola Silva (fabiola.silva@famerp.br) on 2018-01-17T11:04:30Z No. of bitstreams: 1 kleberrobertosantanna_dissert.pdf: 2567533 bytes, checksum: eae324ad76ed0dfd667eaf47bad5c5ea (MD5)Made available in DSpace on 2018-01-17T11:04:30Z (GMT). No. of bitstreams: 1 kleberrobertosantanna_dissert.pdf: 2567533 bytes, checksum: eae324ad76ed0dfd667eaf47bad5c5ea (MD5) Previous issue date: 2017-03-08application/pdfporFaculdade de Medicina de São José do Rio PretoPrograma de Pós-Graduação em Ciências da Saúde::6954410853678806574::600FAMERPBrasilFaculdade 1::Departamento 1::306626487509624506::500LymphedemaRadionuclide ImagingEpidemiologyDiagnosisLinfedemaCintilografiaEpidemiologiaDiagnósticoCIENCIAS DA SAUDE::8765449414823306929::600Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferioresinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da FAMERPinstname:Faculdade de Medicina de São José do Rio Preto (FAMERP)instacron:FAMERPORIGINALkleberrobertosantanna_dissert.pdfkleberrobertosantanna_dissert.pdfapplication/pdf2567533eae324ad76ed0dfd667eaf47bad5c5eaMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165bd3efa91386c1718a7f26a329fdcb468MD53http://bdtd.famerp.br/bitstream/tede/394/2/kleberrobertosantanna_dissert.pdfhttp://bdtd.famerp.br/bitstream/tede/394/3/license.txttede/3942019-02-04 11:06:09.875oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bdtd.famerp.br/PUBhttps://bdtd.famerp.br/oai/requestsbdc@famerp.br||joao.junior@famerp.bropendoar:47112019-02-04T13:06:09Biblioteca Digital de Teses e Dissertações da FAMERP - Faculdade de Medicina de São José do Rio Preto (FAMERP)false |
dc.title.por.fl_str_mv |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
title |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
spellingShingle |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores Sant'Anna, Kleber Roberto Lymphedema Radionuclide Imaging Epidemiology Diagnosis Linfedema Cintilografia Epidemiologia Diagnóstico CIENCIAS DA SAUDE::8765449414823306929::600 |
title_short |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
title_full |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
title_fullStr |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
title_full_unstemmed |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
title_sort |
Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores |
author |
Sant'Anna, Kleber Roberto |
author_facet |
Sant'Anna, Kleber Roberto |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Godoy, Maria de Fátima Guerreiro |
dc.contributor.advisor-co1.fl_str_mv |
Godoy, José Maria Pereira de |
dc.contributor.referee1.fl_str_mv |
Iozzi-klein, Adriana |
dc.contributor.referee2.fl_str_mv |
Monteiro Neto, Luis Ferreira |
dc.contributor.authorID.fl_str_mv |
14785450894 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/5432800503774985 |
dc.contributor.author.fl_str_mv |
Sant'Anna, Kleber Roberto |
contributor_str_mv |
Godoy, Maria de Fátima Guerreiro Godoy, José Maria Pereira de Iozzi-klein, Adriana Monteiro Neto, Luis Ferreira |
dc.subject.eng.fl_str_mv |
Lymphedema Radionuclide Imaging Epidemiology Diagnosis |
topic |
Lymphedema Radionuclide Imaging Epidemiology Diagnosis Linfedema Cintilografia Epidemiologia Diagnóstico CIENCIAS DA SAUDE::8765449414823306929::600 |
dc.subject.por.fl_str_mv |
Linfedema Cintilografia Epidemiologia Diagnóstico |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::8765449414823306929::600 |
description |
Introduction: Lymphedema is a clinical condition in which there is an accumulation of macromolecules in the interstitial space. As a result, it promotes water retention, consequently a failure in the formation or lymph drainage. Objectives: To access the images obtained from Computed Scintigraphy Chamber through a specific protocol of Lymphoscintigraphy and associate them to epidemiological data such as gender, age, educational level, socioeconomic status and prevalence of Lymphedema. Method: Epidemiological data were evaluated in a quantitative cross-sectional study comparing the diagnostic results for Lymphedema of the lower limbs using the Lymphoscintigraphy. They were correlated with gender, age, education level, family income and prevalence among the lower limbs at Hospital de Base in the last 10 years, 2006 to 2016. All patients clinically suspected of Lymphedema of the lower limbs were included and lymphoscintigraphic examinations of the upper limbs were excluded. Descriptive data were considered, and Fisher's exact test was used to correlate these variables considering alpha error of 5%. Results: A total of 430 patients were analyzed, 320(74.42%) were female and 110 (25.58%) male patients. Their age ranged from 10 to 90 years (mean = 48 years). A total 199 (46.27%) were positive findings and 231 (53.73%) negative. Among the images analyzed as positive; female patients were the majority, 183 (91.95%); Fisher's exact test p-value <0.001. When comparing patients with the first grade of high school with patients with complete college education, it was clear that Lymphedema was more prevalent in the first grade of high school, according to Fisher's exact test, p<0.0001. Comparing the second grade of high school with the ones with college education, it was observed that Lymphedema was more prevalent in those with high school; Fisher's exact test, p<0.0001. When comparing the wage gain from one to three minimum wages per month with three to five gains, five to seven and over seven salaries, a higher prevalence of Lymphedema was observed in the group of one to three salaries in relation to the others by Fisher's exact test, p<0.0001 in all evaluations. Comparing the salary range of three to five salaries with the salary range of five to seven and over seven monthly minimum wages, greater prevalence was observed in the range of three to five minimum wages; Fisher's exact test, p<0, 0.001 in both comparisons. The right lower limb presented 65 patients (32.66%), and 87(43.71%) unilateral left limb and 7 patients (23.63%), bilaterally were found. The left side was more prevalent than the right side; Fisher's exact test, p<0.01. Conclusions: Lymphedema is a public health issue that affects mostly women from lower cultural-educational socioeconomic status. One-sided onset can occur in the limb, but bilateral occurrence is frequent and Lymphoscintigraphy is useful in defining the diagnosis in cases of doubt. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017-03-08 |
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2018-01-17T11:04:30Z |
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Sant'Anna, Kleber Roberto. Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores. 2017. 43 f. Dissertação (Programa de Pós-Graduação em Ciências da Saúde) - Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto. |
dc.identifier.uri.fl_str_mv |
http://bdtd.famerp.br/handle/tede/394 |
dc.identifier.doi.por.fl_str_mv |
1296 |
identifier_str_mv |
Sant'Anna, Kleber Roberto. Avaliação de dados epidemiológicos nas linfocintilografias de extremidades inferiores. 2017. 43 f. Dissertação (Programa de Pós-Graduação em Ciências da Saúde) - Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto. 1296 |
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