Tratamento ambulatorial da endocardite estreptocócica

Detalhes bibliográficos
Autor(a) principal: Hassem Sobrinho, Sírio
Data de Publicação: 2010
Tipo de documento: Tese
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da FAMERP
Texto Completo: http://bdtd.famerp.br/handle/tede/126
Resumo: Bacterial endocarditis is a serious infectious disease, the treatment of which is traditionally performed with the patient hospitalized and receiving intravenous medication. When the etiological agent is Streptococcus, progression is generally less aggressive. Thus, the possibility of outpatient treatment becomes an attractive option from the social and economic standpoint. In the literature, this type of treatment is known as outpatient parenteral antimicrobial therapy (OPAT). Objective: The aim of the present study was to demonstrate that outpatient treatment is safe and effective in cases of streptococcic endocarditis. Patients and Methods: Six patients with bacterial endocarditis, diagnosed using the modified Duke University criteria, were followed up between January 2006 and November 2008. Four patients were female (66.6%) and two were male (33.4%). Mean age was 47.8 years, ranging from 32 to 65 years. All patients were eligible for outpatient treatment and agreed to take part in the study, having been either partially or wholly treated in an outpatient regimen. xiii Imaging and laboratory exams were performed at the beginning and end of treatment and when otherwise deemed necessary. Results: All patients progressed with no complications and with the complete resolution of the infection. The results of the laboratory and imaging exams are presented and discussed. Conclusion: Streptococcic bacterial endocarditis may be safely and effectively treated in an outpatient regimen for selected patients with no concomitant aggravating factors.
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spelling Godoy, Moacir Fernandes deCPF:57095256853http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4787885D5&dataRevisao=nullCrotti, Ulisses AlexandreCPF:00000000044Moscardini, Airton CamachoCPF:27424421972http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4731967J8&dataRevisao=nullJacob, José Luiz BalthazarCPF:00000000444http://lattes.cnpq.br/0800861496403513Braga, João Carlos FerreiraCPF:00000000445http://lattes.cnpq.br/4251168533443524CPF:01876451831http://lattes.cnpq.br/4185664972551441Hassem Sobrinho, Sírio2016-01-26T12:51:34Z2012-07-302010-07-16HASSEM SOBRINHO, Sírio. Tratamento ambulatorial da endocardite estreptocócica. 2010. 148 f. Tese (Doutorado em Medicina Interna; Medicina e Ciências Correlatas) - Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, 2010.http://bdtd.famerp.br/handle/tede/126Bacterial endocarditis is a serious infectious disease, the treatment of which is traditionally performed with the patient hospitalized and receiving intravenous medication. When the etiological agent is Streptococcus, progression is generally less aggressive. Thus, the possibility of outpatient treatment becomes an attractive option from the social and economic standpoint. In the literature, this type of treatment is known as outpatient parenteral antimicrobial therapy (OPAT). Objective: The aim of the present study was to demonstrate that outpatient treatment is safe and effective in cases of streptococcic endocarditis. Patients and Methods: Six patients with bacterial endocarditis, diagnosed using the modified Duke University criteria, were followed up between January 2006 and November 2008. Four patients were female (66.6%) and two were male (33.4%). Mean age was 47.8 years, ranging from 32 to 65 years. All patients were eligible for outpatient treatment and agreed to take part in the study, having been either partially or wholly treated in an outpatient regimen. xiii Imaging and laboratory exams were performed at the beginning and end of treatment and when otherwise deemed necessary. Results: All patients progressed with no complications and with the complete resolution of the infection. The results of the laboratory and imaging exams are presented and discussed. Conclusion: Streptococcic bacterial endocarditis may be safely and effectively treated in an outpatient regimen for selected patients with no concomitant aggravating factors.A Endocardite bacteriana é uma grave doença infecciosa cujo tratamento é tradicionalmente feito com o paciente internado, recebendo medicação intravenosa. As endocardites cujo agente etiológico é o Streptococcus costumam ter evolução menos agressiva. Assim, a possibilidade de tratamento ambulatorial passa a ser atraente tanto do ponto de vista social como econômico. Esse tipo de tratamento é conhecido na literatura pela sigla OPAT (Outpatient Parenteral Antimicrobial Therapy) Objetivo: O objetivo deste estudo foi demonstrar que, em casos de endocardite estreptocócica bem selecionados, o tratamento ambulatorial é seguro e eficaz. Casuística e Método: Foram acompanhados seis pacientes com endocardite bacteriana por Streptococcus, diagnosticados pelos critérios modificados da Universidade de Duke, no período de janeiro de 2006 a novembro de 2008. Quatro pacientes eram do sexo feminino (66,6%) e dois eram do sexo masculino (33.4%). A idade média foi de 47,8 anos, variando de 32 a 65 anos. xi Todos os pacientes que eram elegíveis para o tratamento ambulatorial concordaram em fazer parte do estudo tendo sido tratados parcialmente ou integralmente em regime ambulatorial. Os exames de imagem e laboratoriais eram feitos no início e ao final do tratamento ou de acordo com a necessidade Resultado: Todos evoluíram sem complicações e com resolução completa do quadro infeccioso. São apresentados e comentados os resultados evolutivos dos exames laboratoriais e de imagem realizados. Conclusão: A endocardite bacteriana Estreptocócica pode ser tratada de forma segura em regime ambulatorial em pacientes selecionados, nos quais não existe concomitância de fatores agravantes, com conseqüente benefício para o paciente.Made available in DSpace on 2016-01-26T12:51:34Z (GMT). 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dc.title.por.fl_str_mv Tratamento ambulatorial da endocardite estreptocócica
title Tratamento ambulatorial da endocardite estreptocócica
spellingShingle Tratamento ambulatorial da endocardite estreptocócica
Hassem Sobrinho, Sírio
Streptococcic endocarditis
Bacterial endocarditis
Outpatient treatment
Streptococcus
OPAT
Cardiology
Endocarditis, Bacterial
Endocardite Estreptocócica
Endocardite Infecciosa
Tratamento ambulatorial
Treptococcus
OPAT
Endocardite Bacteriana
Endocarditis Bacteriana
CNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::CARDIOLOGIA::123123123123::600
title_short Tratamento ambulatorial da endocardite estreptocócica
title_full Tratamento ambulatorial da endocardite estreptocócica
title_fullStr Tratamento ambulatorial da endocardite estreptocócica
title_full_unstemmed Tratamento ambulatorial da endocardite estreptocócica
title_sort Tratamento ambulatorial da endocardite estreptocócica
author Hassem Sobrinho, Sírio
author_facet Hassem Sobrinho, Sírio
author_role author
dc.contributor.advisor1.fl_str_mv Godoy, Moacir Fernandes de
dc.contributor.advisor1ID.fl_str_mv CPF:57095256853
dc.contributor.advisor1Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4787885D5&dataRevisao=null
dc.contributor.referee1.fl_str_mv Crotti, Ulisses Alexandre
dc.contributor.referee1ID.fl_str_mv CPF:00000000044
dc.contributor.referee2.fl_str_mv Moscardini, Airton Camacho
dc.contributor.referee2ID.fl_str_mv CPF:27424421972
dc.contributor.referee2Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4731967J8&dataRevisao=null
dc.contributor.referee3.fl_str_mv Jacob, José Luiz Balthazar
dc.contributor.referee3ID.fl_str_mv CPF:00000000444
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/0800861496403513
dc.contributor.referee4.fl_str_mv Braga, João Carlos Ferreira
dc.contributor.referee4ID.fl_str_mv CPF:00000000445
dc.contributor.referee4Lattes.fl_str_mv http://lattes.cnpq.br/4251168533443524
dc.contributor.authorID.fl_str_mv CPF:01876451831
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/4185664972551441
dc.contributor.author.fl_str_mv Hassem Sobrinho, Sírio
contributor_str_mv Godoy, Moacir Fernandes de
Crotti, Ulisses Alexandre
Moscardini, Airton Camacho
Jacob, José Luiz Balthazar
Braga, João Carlos Ferreira
dc.subject.eng.fl_str_mv Streptococcic endocarditis
Bacterial endocarditis
Outpatient treatment
Streptococcus
OPAT
Cardiology
Endocarditis, Bacterial
topic Streptococcic endocarditis
Bacterial endocarditis
Outpatient treatment
Streptococcus
OPAT
Cardiology
Endocarditis, Bacterial
Endocardite Estreptocócica
Endocardite Infecciosa
Tratamento ambulatorial
Treptococcus
OPAT
Endocardite Bacteriana
Endocarditis Bacteriana
CNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::CARDIOLOGIA::123123123123::600
dc.subject.por.fl_str_mv Endocardite Estreptocócica
Endocardite Infecciosa
Tratamento ambulatorial
Treptococcus
OPAT
Endocardite Bacteriana
dc.subject.spa.fl_str_mv Endocarditis Bacteriana
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::CARDIOLOGIA::123123123123::600
description Bacterial endocarditis is a serious infectious disease, the treatment of which is traditionally performed with the patient hospitalized and receiving intravenous medication. When the etiological agent is Streptococcus, progression is generally less aggressive. Thus, the possibility of outpatient treatment becomes an attractive option from the social and economic standpoint. In the literature, this type of treatment is known as outpatient parenteral antimicrobial therapy (OPAT). Objective: The aim of the present study was to demonstrate that outpatient treatment is safe and effective in cases of streptococcic endocarditis. Patients and Methods: Six patients with bacterial endocarditis, diagnosed using the modified Duke University criteria, were followed up between January 2006 and November 2008. Four patients were female (66.6%) and two were male (33.4%). Mean age was 47.8 years, ranging from 32 to 65 years. All patients were eligible for outpatient treatment and agreed to take part in the study, having been either partially or wholly treated in an outpatient regimen. xiii Imaging and laboratory exams were performed at the beginning and end of treatment and when otherwise deemed necessary. Results: All patients progressed with no complications and with the complete resolution of the infection. The results of the laboratory and imaging exams are presented and discussed. Conclusion: Streptococcic bacterial endocarditis may be safely and effectively treated in an outpatient regimen for selected patients with no concomitant aggravating factors.
publishDate 2010
dc.date.issued.fl_str_mv 2010-07-16
dc.date.available.fl_str_mv 2012-07-30
dc.date.accessioned.fl_str_mv 2016-01-26T12:51:34Z
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dc.identifier.citation.fl_str_mv HASSEM SOBRINHO, Sírio. Tratamento ambulatorial da endocardite estreptocócica. 2010. 148 f. Tese (Doutorado em Medicina Interna; Medicina e Ciências Correlatas) - Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, 2010.
dc.identifier.uri.fl_str_mv http://bdtd.famerp.br/handle/tede/126
identifier_str_mv HASSEM SOBRINHO, Sírio. Tratamento ambulatorial da endocardite estreptocócica. 2010. 148 f. Tese (Doutorado em Medicina Interna; Medicina e Ciências Correlatas) - Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, 2010.
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dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Ciências da Saúde::123123123123::600
dc.publisher.initials.fl_str_mv FAMERP
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dc.publisher.department.fl_str_mv Medicina Interna; Medicina e Ciências Correlatas::123123123123::600
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