Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus

Detalhes bibliográficos
Autor(a) principal: Hora,Laís Cristine Delgado da
Data de Publicação: 2022
Outros Autores: Muniz,Lilian Ferreira, Griz,Silvana Maria Sobral, Silva,Jéssica Dayane da, Britto,Diana Babini Lapa de Albuquerque, Venâncio,Leonardo Gleygson Angelo, Miranda Filho,Demócrito de Barros, Leal,Mariana de Carvalho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Archives of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380
Resumo: Abstract Introduction Prenatal exposure to the Zika virus can impair neurodevelopment and cause auditory damage. Objective To analyze the frequency-following response (FFR) and the auditory behavior (with the LittlEars® questionnaire) of children with and without prenatal exposure to Zika virus infection. Methods A total of 30 children participated in the present study, divided into 3 groups: 10 children with microcephaly and prenatal exposure to the Zika virus; 10 normocephalic children with prenatal exposure to the Zika virus; and 10 children with no evidence of prenatal exposure to the virus. The FFR test was performed with the /da/ syllable. The LittlEars® questionnaire was used with parents/guardians. Results For the FFR measurements, there was no difference between the groups. The children with exposure to the Zika virus presented a final score in the questionnaire below what is expected from children with normal hearing. A significant difference was observed for the final, semantic, and expressive scores between the group with microcephaly and the other groups. A strong negative correlation was seen between the LittlEars® questionnaire final score and the FFR measurements for the group with microcephaly when compared with the other groups. Conclusion Children exposed to the Zika virus, with and without microcephaly, presented FFR patterns similar to what was seen in children with no evidence of virus exposure. However, they showed signs of immature auditory behavior, suggesting auditory development delay.
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spelling Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Viruszika virusmicrocephalysurveys and questionnairesfrequency-following responsespeech-evoked auditory brainstem responseevoked potentialsauditory brain stemAbstract Introduction Prenatal exposure to the Zika virus can impair neurodevelopment and cause auditory damage. Objective To analyze the frequency-following response (FFR) and the auditory behavior (with the LittlEars® questionnaire) of children with and without prenatal exposure to Zika virus infection. Methods A total of 30 children participated in the present study, divided into 3 groups: 10 children with microcephaly and prenatal exposure to the Zika virus; 10 normocephalic children with prenatal exposure to the Zika virus; and 10 children with no evidence of prenatal exposure to the virus. The FFR test was performed with the /da/ syllable. The LittlEars® questionnaire was used with parents/guardians. Results For the FFR measurements, there was no difference between the groups. The children with exposure to the Zika virus presented a final score in the questionnaire below what is expected from children with normal hearing. A significant difference was observed for the final, semantic, and expressive scores between the group with microcephaly and the other groups. A strong negative correlation was seen between the LittlEars® questionnaire final score and the FFR measurements for the group with microcephaly when compared with the other groups. Conclusion Children exposed to the Zika virus, with and without microcephaly, presented FFR patterns similar to what was seen in children with no evidence of virus exposure. However, they showed signs of immature auditory behavior, suggesting auditory development delay.Fundação Otorrinolaringologia2022-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380International Archives of Otorhinolaryngology v.26 n.3 2022reponame:International Archives of Otorhinolaryngologyinstname:Fundação Otorrinolaringologia (FORL)instacron:FORL10.1055/s-0041-1726048info:eu-repo/semantics/openAccessHora,Laís Cristine Delgado daMuniz,Lilian FerreiraGriz,Silvana Maria SobralSilva,Jéssica Dayane daBritto,Diana Babini Lapa de AlbuquerqueVenâncio,Leonardo Gleygson AngeloMiranda Filho,Demócrito de BarrosLeal,Mariana de Carvalhoeng2022-11-01T00:00:00Zoai:scielo:S1809-48642022000300380Revistahttps://www.scielo.br/j/iao/https://old.scielo.br/oai/scielo-oai.php||iaorl@iaorl.org||archives@internationalarchivesent.org||arquivos@forl.org.br1809-48641809-4864opendoar:2022-11-01T00:00International Archives of Otorhinolaryngology - Fundação Otorrinolaringologia (FORL)false
dc.title.none.fl_str_mv Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
title Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
spellingShingle Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
Hora,Laís Cristine Delgado da
zika virus
microcephaly
surveys and questionnaires
frequency-following response
speech-evoked auditory brainstem response
evoked potentials
auditory brain stem
title_short Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
title_full Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
title_fullStr Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
title_full_unstemmed Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
title_sort Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
author Hora,Laís Cristine Delgado da
author_facet Hora,Laís Cristine Delgado da
Muniz,Lilian Ferreira
Griz,Silvana Maria Sobral
Silva,Jéssica Dayane da
Britto,Diana Babini Lapa de Albuquerque
Venâncio,Leonardo Gleygson Angelo
Miranda Filho,Demócrito de Barros
Leal,Mariana de Carvalho
author_role author
author2 Muniz,Lilian Ferreira
Griz,Silvana Maria Sobral
Silva,Jéssica Dayane da
Britto,Diana Babini Lapa de Albuquerque
Venâncio,Leonardo Gleygson Angelo
Miranda Filho,Demócrito de Barros
Leal,Mariana de Carvalho
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Hora,Laís Cristine Delgado da
Muniz,Lilian Ferreira
Griz,Silvana Maria Sobral
Silva,Jéssica Dayane da
Britto,Diana Babini Lapa de Albuquerque
Venâncio,Leonardo Gleygson Angelo
Miranda Filho,Demócrito de Barros
Leal,Mariana de Carvalho
dc.subject.por.fl_str_mv zika virus
microcephaly
surveys and questionnaires
frequency-following response
speech-evoked auditory brainstem response
evoked potentials
auditory brain stem
topic zika virus
microcephaly
surveys and questionnaires
frequency-following response
speech-evoked auditory brainstem response
evoked potentials
auditory brain stem
description Abstract Introduction Prenatal exposure to the Zika virus can impair neurodevelopment and cause auditory damage. Objective To analyze the frequency-following response (FFR) and the auditory behavior (with the LittlEars® questionnaire) of children with and without prenatal exposure to Zika virus infection. Methods A total of 30 children participated in the present study, divided into 3 groups: 10 children with microcephaly and prenatal exposure to the Zika virus; 10 normocephalic children with prenatal exposure to the Zika virus; and 10 children with no evidence of prenatal exposure to the virus. The FFR test was performed with the /da/ syllable. The LittlEars® questionnaire was used with parents/guardians. Results For the FFR measurements, there was no difference between the groups. The children with exposure to the Zika virus presented a final score in the questionnaire below what is expected from children with normal hearing. A significant difference was observed for the final, semantic, and expressive scores between the group with microcephaly and the other groups. A strong negative correlation was seen between the LittlEars® questionnaire final score and the FFR measurements for the group with microcephaly when compared with the other groups. Conclusion Children exposed to the Zika virus, with and without microcephaly, presented FFR patterns similar to what was seen in children with no evidence of virus exposure. However, they showed signs of immature auditory behavior, suggesting auditory development delay.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1055/s-0041-1726048
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Fundação Otorrinolaringologia
publisher.none.fl_str_mv Fundação Otorrinolaringologia
dc.source.none.fl_str_mv International Archives of Otorhinolaryngology v.26 n.3 2022
reponame:International Archives of Otorhinolaryngology
instname:Fundação Otorrinolaringologia (FORL)
instacron:FORL
instname_str Fundação Otorrinolaringologia (FORL)
instacron_str FORL
institution FORL
reponame_str International Archives of Otorhinolaryngology
collection International Archives of Otorhinolaryngology
repository.name.fl_str_mv International Archives of Otorhinolaryngology - Fundação Otorrinolaringologia (FORL)
repository.mail.fl_str_mv ||iaorl@iaorl.org||archives@internationalarchivesent.org||arquivos@forl.org.br
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