Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Archives of Otorhinolaryngology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380 |
Resumo: | Abstract Introduction Prenatal exposure to the Zika virus can impair neurodevelopment and cause auditory damage. Objective To analyze the frequency-following response (FFR) and the auditory behavior (with the LittlEars® questionnaire) of children with and without prenatal exposure to Zika virus infection. Methods A total of 30 children participated in the present study, divided into 3 groups: 10 children with microcephaly and prenatal exposure to the Zika virus; 10 normocephalic children with prenatal exposure to the Zika virus; and 10 children with no evidence of prenatal exposure to the virus. The FFR test was performed with the /da/ syllable. The LittlEars® questionnaire was used with parents/guardians. Results For the FFR measurements, there was no difference between the groups. The children with exposure to the Zika virus presented a final score in the questionnaire below what is expected from children with normal hearing. A significant difference was observed for the final, semantic, and expressive scores between the group with microcephaly and the other groups. A strong negative correlation was seen between the LittlEars® questionnaire final score and the FFR measurements for the group with microcephaly when compared with the other groups. Conclusion Children exposed to the Zika virus, with and without microcephaly, presented FFR patterns similar to what was seen in children with no evidence of virus exposure. However, they showed signs of immature auditory behavior, suggesting auditory development delay. |
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Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Viruszika virusmicrocephalysurveys and questionnairesfrequency-following responsespeech-evoked auditory brainstem responseevoked potentialsauditory brain stemAbstract Introduction Prenatal exposure to the Zika virus can impair neurodevelopment and cause auditory damage. Objective To analyze the frequency-following response (FFR) and the auditory behavior (with the LittlEars® questionnaire) of children with and without prenatal exposure to Zika virus infection. Methods A total of 30 children participated in the present study, divided into 3 groups: 10 children with microcephaly and prenatal exposure to the Zika virus; 10 normocephalic children with prenatal exposure to the Zika virus; and 10 children with no evidence of prenatal exposure to the virus. The FFR test was performed with the /da/ syllable. The LittlEars® questionnaire was used with parents/guardians. Results For the FFR measurements, there was no difference between the groups. The children with exposure to the Zika virus presented a final score in the questionnaire below what is expected from children with normal hearing. A significant difference was observed for the final, semantic, and expressive scores between the group with microcephaly and the other groups. A strong negative correlation was seen between the LittlEars® questionnaire final score and the FFR measurements for the group with microcephaly when compared with the other groups. Conclusion Children exposed to the Zika virus, with and without microcephaly, presented FFR patterns similar to what was seen in children with no evidence of virus exposure. However, they showed signs of immature auditory behavior, suggesting auditory development delay.Fundação Otorrinolaringologia2022-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380International Archives of Otorhinolaryngology v.26 n.3 2022reponame:International Archives of Otorhinolaryngologyinstname:Fundação Otorrinolaringologia (FORL)instacron:FORL10.1055/s-0041-1726048info:eu-repo/semantics/openAccessHora,Laís Cristine Delgado daMuniz,Lilian FerreiraGriz,Silvana Maria SobralSilva,Jéssica Dayane daBritto,Diana Babini Lapa de AlbuquerqueVenâncio,Leonardo Gleygson AngeloMiranda Filho,Demócrito de BarrosLeal,Mariana de Carvalhoeng2022-11-01T00:00:00Zoai:scielo:S1809-48642022000300380Revistahttps://www.scielo.br/j/iao/https://old.scielo.br/oai/scielo-oai.php||iaorl@iaorl.org||archives@internationalarchivesent.org||arquivos@forl.org.br1809-48641809-4864opendoar:2022-11-01T00:00International Archives of Otorhinolaryngology - Fundação Otorrinolaringologia (FORL)false |
dc.title.none.fl_str_mv |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
title |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
spellingShingle |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus Hora,Laís Cristine Delgado da zika virus microcephaly surveys and questionnaires frequency-following response speech-evoked auditory brainstem response evoked potentials auditory brain stem |
title_short |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
title_full |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
title_fullStr |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
title_full_unstemmed |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
title_sort |
Frequency-Following Response and Auditory Behavior in Children with Prenatal Exposure to the Zika Virus |
author |
Hora,Laís Cristine Delgado da |
author_facet |
Hora,Laís Cristine Delgado da Muniz,Lilian Ferreira Griz,Silvana Maria Sobral Silva,Jéssica Dayane da Britto,Diana Babini Lapa de Albuquerque Venâncio,Leonardo Gleygson Angelo Miranda Filho,Demócrito de Barros Leal,Mariana de Carvalho |
author_role |
author |
author2 |
Muniz,Lilian Ferreira Griz,Silvana Maria Sobral Silva,Jéssica Dayane da Britto,Diana Babini Lapa de Albuquerque Venâncio,Leonardo Gleygson Angelo Miranda Filho,Demócrito de Barros Leal,Mariana de Carvalho |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Hora,Laís Cristine Delgado da Muniz,Lilian Ferreira Griz,Silvana Maria Sobral Silva,Jéssica Dayane da Britto,Diana Babini Lapa de Albuquerque Venâncio,Leonardo Gleygson Angelo Miranda Filho,Demócrito de Barros Leal,Mariana de Carvalho |
dc.subject.por.fl_str_mv |
zika virus microcephaly surveys and questionnaires frequency-following response speech-evoked auditory brainstem response evoked potentials auditory brain stem |
topic |
zika virus microcephaly surveys and questionnaires frequency-following response speech-evoked auditory brainstem response evoked potentials auditory brain stem |
description |
Abstract Introduction Prenatal exposure to the Zika virus can impair neurodevelopment and cause auditory damage. Objective To analyze the frequency-following response (FFR) and the auditory behavior (with the LittlEars® questionnaire) of children with and without prenatal exposure to Zika virus infection. Methods A total of 30 children participated in the present study, divided into 3 groups: 10 children with microcephaly and prenatal exposure to the Zika virus; 10 normocephalic children with prenatal exposure to the Zika virus; and 10 children with no evidence of prenatal exposure to the virus. The FFR test was performed with the /da/ syllable. The LittlEars® questionnaire was used with parents/guardians. Results For the FFR measurements, there was no difference between the groups. The children with exposure to the Zika virus presented a final score in the questionnaire below what is expected from children with normal hearing. A significant difference was observed for the final, semantic, and expressive scores between the group with microcephaly and the other groups. A strong negative correlation was seen between the LittlEars® questionnaire final score and the FFR measurements for the group with microcephaly when compared with the other groups. Conclusion Children exposed to the Zika virus, with and without microcephaly, presented FFR patterns similar to what was seen in children with no evidence of virus exposure. However, they showed signs of immature auditory behavior, suggesting auditory development delay. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-48642022000300380 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1055/s-0041-1726048 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Fundação Otorrinolaringologia |
publisher.none.fl_str_mv |
Fundação Otorrinolaringologia |
dc.source.none.fl_str_mv |
International Archives of Otorhinolaryngology v.26 n.3 2022 reponame:International Archives of Otorhinolaryngology instname:Fundação Otorrinolaringologia (FORL) instacron:FORL |
instname_str |
Fundação Otorrinolaringologia (FORL) |
instacron_str |
FORL |
institution |
FORL |
reponame_str |
International Archives of Otorhinolaryngology |
collection |
International Archives of Otorhinolaryngology |
repository.name.fl_str_mv |
International Archives of Otorhinolaryngology - Fundação Otorrinolaringologia (FORL) |
repository.mail.fl_str_mv |
||iaorl@iaorl.org||archives@internationalarchivesent.org||arquivos@forl.org.br |
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1754203977480667136 |