Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review

Detalhes bibliográficos
Autor(a) principal: Aidar, Joana Trosdolf
Data de Publicação: 2022
Outros Autores: Gomes, Ana Carolina Lopacinski, Ribeiro, Elaine Rossi, Czepula, Alexandra, Nieto, Gislayne Castro e Souza de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Espaço para a Saúde (Online)
Texto Completo: https://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/869
Resumo: We sought to analyze the adverse reactions of montelukast when prescribed for the treatment of pediatric asthma. Integrative literature review using the databases: U.S. National Library of Medicine (PubMed), Virtual Health Library (BVS), SCOPUS and Business Source Complete (EBSCO), using the descriptors: "asthma", "pediatric", "montelukast" and "adverse effects", joined by the Boolean “ AND''. Articles were included in their entirety, published in the last 5 years, written in Portuguese, English or Spanish, researched in humans and related to our objective. Those that met our exclusion criteria were excluded. Fifty-three articles were identified, of which 11 comprised the final sample of this review. Exposure to montelukast was associated with a 2-fold greater chance of neuropsychiatric reactions in one of the analyzed articles, but the studies have not yet provided a common pathophysiological explanation. Reactions neuropsychiatric disorders were the most prevalent, representing more than 90% of the sample.
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spelling Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature reviewReações adversas do montelucaste no tratamento da asma pediátrica: uma revisão integrativa da literaturaAsmaPediatriaMontelucasteAsthmaPediatricMontelukastWe sought to analyze the adverse reactions of montelukast when prescribed for the treatment of pediatric asthma. Integrative literature review using the databases: U.S. National Library of Medicine (PubMed), Virtual Health Library (BVS), SCOPUS and Business Source Complete (EBSCO), using the descriptors: "asthma", "pediatric", "montelukast" and "adverse effects", joined by the Boolean “ AND''. Articles were included in their entirety, published in the last 5 years, written in Portuguese, English or Spanish, researched in humans and related to our objective. Those that met our exclusion criteria were excluded. Fifty-three articles were identified, of which 11 comprised the final sample of this review. Exposure to montelukast was associated with a 2-fold greater chance of neuropsychiatric reactions in one of the analyzed articles, but the studies have not yet provided a common pathophysiological explanation. Reactions neuropsychiatric disorders were the most prevalent, representing more than 90% of the sample.Buscou-se analisar as reações adversas do montelucaste quando prescrito para o tratamento da asma pediátrica. Revisão integrativa da literatura utilizando as bases de dados: U.S. National Library of Medicine (PubMed), Biblioteca Virtual da Saúde (BVS), SCOPUS e Business Source Complete (EBSCO), empregando os descritores: "asthma", “pediatric”, “montelukast” e "adverse effects”, unidos pelo booleano “AND''. Incluíram-se artigos na íntegra; publicados nos últimos 5 anos; redigidos em português, inglês ou espanhol; pesquisados em humanos e com uma relação com o nosso objetivo. Excluíram-se os que se enquadravam em nossos critérios de exclusão. Foram identificados 53 artigos, dos quais 11 compuseram a amostra final desta revisão. A exposição ao montelucaste foi associada a uma chance 2 vezes maior de reações neuropsiquiátricas em um dos artigos analisados, porém os estudos ainda não forneceram uma explicação fisiopatológica em comum. Reações neuropsiquiátricos foram as de maior prevalência, representando mais de 90% da amostra.Faculdades Pequeno Príncipe2022-08-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/86910.22421/1517-7130/es.2022v23.e869Espaço para a Saúde; Vol. 23 (2022)Espaço para a Saúde; v. 23 (2022)1517-71300103-3832reponame:Espaço para a Saúde (Online)instname:Faculdades Pequeno Príncipe (FPP)instacron:FPPporhttps://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/869/673Copyright (c) 2022 Joana Trosdolf Aidar, Ana Carolina Lopacinski Gomes, Elaine Rossi Ribeiro, Alexandra Czepula, Gislayne Castro e Souza de Nietohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAidar, Joana Trosdolf Gomes, Ana Carolina LopacinskiRibeiro, Elaine RossiCzepula, Alexandra Nieto, Gislayne Castro e Souza de2022-12-08T19:13:14Zoai:ojs.168.194.69.20:article/869Revistahttps://espacoparasaude.fpp.edu.br/index.php/espacosaude/PRIhttps://espacoparasaude.fpp.edu.br/index.php/espacosaude/oaiespaco-saude@fpp.edu.br || elaine.rossi@fpp.edu.br1517-71300103-3832opendoar:2022-12-08T19:13:14Espaço para a Saúde (Online) - Faculdades Pequeno Príncipe (FPP)false
dc.title.none.fl_str_mv Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
Reações adversas do montelucaste no tratamento da asma pediátrica: uma revisão integrativa da literatura
title Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
spellingShingle Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
Aidar, Joana Trosdolf
Asma
Pediatria
Montelucaste
Asthma
Pediatric
Montelukast
title_short Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
title_full Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
title_fullStr Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
title_full_unstemmed Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
title_sort Adverse reactions of montelukast in the treatment of pediatric asthma: an integrative literature review
author Aidar, Joana Trosdolf
author_facet Aidar, Joana Trosdolf
Gomes, Ana Carolina Lopacinski
Ribeiro, Elaine Rossi
Czepula, Alexandra
Nieto, Gislayne Castro e Souza de
author_role author
author2 Gomes, Ana Carolina Lopacinski
Ribeiro, Elaine Rossi
Czepula, Alexandra
Nieto, Gislayne Castro e Souza de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Aidar, Joana Trosdolf
Gomes, Ana Carolina Lopacinski
Ribeiro, Elaine Rossi
Czepula, Alexandra
Nieto, Gislayne Castro e Souza de
dc.subject.por.fl_str_mv Asma
Pediatria
Montelucaste
Asthma
Pediatric
Montelukast
topic Asma
Pediatria
Montelucaste
Asthma
Pediatric
Montelukast
description We sought to analyze the adverse reactions of montelukast when prescribed for the treatment of pediatric asthma. Integrative literature review using the databases: U.S. National Library of Medicine (PubMed), Virtual Health Library (BVS), SCOPUS and Business Source Complete (EBSCO), using the descriptors: "asthma", "pediatric", "montelukast" and "adverse effects", joined by the Boolean “ AND''. Articles were included in their entirety, published in the last 5 years, written in Portuguese, English or Spanish, researched in humans and related to our objective. Those that met our exclusion criteria were excluded. Fifty-three articles were identified, of which 11 comprised the final sample of this review. Exposure to montelukast was associated with a 2-fold greater chance of neuropsychiatric reactions in one of the analyzed articles, but the studies have not yet provided a common pathophysiological explanation. Reactions neuropsychiatric disorders were the most prevalent, representing more than 90% of the sample.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/869
10.22421/1517-7130/es.2022v23.e869
url https://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/869
identifier_str_mv 10.22421/1517-7130/es.2022v23.e869
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://espacoparasaude.fpp.edu.br/index.php/espacosaude/article/view/869/673
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Faculdades Pequeno Príncipe
publisher.none.fl_str_mv Faculdades Pequeno Príncipe
dc.source.none.fl_str_mv Espaço para a Saúde; Vol. 23 (2022)
Espaço para a Saúde; v. 23 (2022)
1517-7130
0103-3832
reponame:Espaço para a Saúde (Online)
instname:Faculdades Pequeno Príncipe (FPP)
instacron:FPP
instname_str Faculdades Pequeno Príncipe (FPP)
instacron_str FPP
institution FPP
reponame_str Espaço para a Saúde (Online)
collection Espaço para a Saúde (Online)
repository.name.fl_str_mv Espaço para a Saúde (Online) - Faculdades Pequeno Príncipe (FPP)
repository.mail.fl_str_mv espaco-saude@fpp.edu.br || elaine.rossi@fpp.edu.br
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