Lingual amyloidosis associated to multiple myeloma: case report

Detalhes bibliográficos
Autor(a) principal: LEAL,Gustavo André
Data de Publicação: 2022
Outros Autores: BALLARDIN,Bárbara Soldatelli, RISSETE,Melissa Tomie Mozena, AMENABAR,José Miguel, SCHUSSEL,Juliana Lucena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: RGO - Revista Gaúcha de Odontologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1981-86372022000100812
Resumo: ABSTRACT Oral amyloidosis is a disease characterized by extracellular and irreversible deposition of amorphous and fibrillar proteins in the oral cavity, being strongly associated with Multiple Myeloma. The objective of this study is to report a case of a 62-year-old woman diagnosed with Multiple Myeloma who, approximately 2 years after starting treatment for the underlying disease, presented a lesion on the lateral border of the tongue with exophytic growth, pinkish color, vascularized, painless, measuring 3cm in its largest diameter. After histopathological analysis through incisional biopsy, a final diagnosis of amyloidosis was obtained. As a local treatment, we opted for complete excision of the lesion. The patient evolved to death due to Multiple Myeloma influenced by the diagnosis of systemic amyloidosis. Oral amyloidosis is usually associated with the systemic presentation of the disease, making it necessary to conduct a thorough investigation of other organs. Its diagnosis is important since the prognosis is directly related and can negatively influence survival rates and treatment of the underlying disease.
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spelling Lingual amyloidosis associated to multiple myeloma: case reportAmyloidosisMultiple myelomaOral diagnosisABSTRACT Oral amyloidosis is a disease characterized by extracellular and irreversible deposition of amorphous and fibrillar proteins in the oral cavity, being strongly associated with Multiple Myeloma. The objective of this study is to report a case of a 62-year-old woman diagnosed with Multiple Myeloma who, approximately 2 years after starting treatment for the underlying disease, presented a lesion on the lateral border of the tongue with exophytic growth, pinkish color, vascularized, painless, measuring 3cm in its largest diameter. After histopathological analysis through incisional biopsy, a final diagnosis of amyloidosis was obtained. As a local treatment, we opted for complete excision of the lesion. The patient evolved to death due to Multiple Myeloma influenced by the diagnosis of systemic amyloidosis. Oral amyloidosis is usually associated with the systemic presentation of the disease, making it necessary to conduct a thorough investigation of other organs. Its diagnosis is important since the prognosis is directly related and can negatively influence survival rates and treatment of the underlying disease.Faculdade São Leopoldo Mandic2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1981-86372022000100812RGO - Revista Gaúcha de Odontologia v.70 2022reponame:RGO - Revista Gaúcha de Odontologia (Online)instname:Faculdade São Leopoldo Mandic (FSLM)instacron:FSLM10.1590/1981-86372022002920210002info:eu-repo/semantics/openAccessLEAL,Gustavo AndréBALLARDIN,Bárbara SoldatelliRISSETE,Melissa Tomie MozenaAMENABAR,José MiguelSCHUSSEL,Juliana Lucenaeng2022-09-05T00:00:00Zoai:scielo:S1981-86372022000100812Revistahttp://revodonto.bvsalud.org/scielo.php?script=sci_serial&pid=1981-8637&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||contato@revistargo.com.br1981-86370103-6971opendoar:2022-09-05T00:00RGO - Revista Gaúcha de Odontologia (Online) - Faculdade São Leopoldo Mandic (FSLM)false
dc.title.none.fl_str_mv Lingual amyloidosis associated to multiple myeloma: case report
title Lingual amyloidosis associated to multiple myeloma: case report
spellingShingle Lingual amyloidosis associated to multiple myeloma: case report
LEAL,Gustavo André
Amyloidosis
Multiple myeloma
Oral diagnosis
title_short Lingual amyloidosis associated to multiple myeloma: case report
title_full Lingual amyloidosis associated to multiple myeloma: case report
title_fullStr Lingual amyloidosis associated to multiple myeloma: case report
title_full_unstemmed Lingual amyloidosis associated to multiple myeloma: case report
title_sort Lingual amyloidosis associated to multiple myeloma: case report
author LEAL,Gustavo André
author_facet LEAL,Gustavo André
BALLARDIN,Bárbara Soldatelli
RISSETE,Melissa Tomie Mozena
AMENABAR,José Miguel
SCHUSSEL,Juliana Lucena
author_role author
author2 BALLARDIN,Bárbara Soldatelli
RISSETE,Melissa Tomie Mozena
AMENABAR,José Miguel
SCHUSSEL,Juliana Lucena
author2_role author
author
author
author
dc.contributor.author.fl_str_mv LEAL,Gustavo André
BALLARDIN,Bárbara Soldatelli
RISSETE,Melissa Tomie Mozena
AMENABAR,José Miguel
SCHUSSEL,Juliana Lucena
dc.subject.por.fl_str_mv Amyloidosis
Multiple myeloma
Oral diagnosis
topic Amyloidosis
Multiple myeloma
Oral diagnosis
description ABSTRACT Oral amyloidosis is a disease characterized by extracellular and irreversible deposition of amorphous and fibrillar proteins in the oral cavity, being strongly associated with Multiple Myeloma. The objective of this study is to report a case of a 62-year-old woman diagnosed with Multiple Myeloma who, approximately 2 years after starting treatment for the underlying disease, presented a lesion on the lateral border of the tongue with exophytic growth, pinkish color, vascularized, painless, measuring 3cm in its largest diameter. After histopathological analysis through incisional biopsy, a final diagnosis of amyloidosis was obtained. As a local treatment, we opted for complete excision of the lesion. The patient evolved to death due to Multiple Myeloma influenced by the diagnosis of systemic amyloidosis. Oral amyloidosis is usually associated with the systemic presentation of the disease, making it necessary to conduct a thorough investigation of other organs. Its diagnosis is important since the prognosis is directly related and can negatively influence survival rates and treatment of the underlying disease.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1981-86372022002920210002
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dc.publisher.none.fl_str_mv Faculdade São Leopoldo Mandic
publisher.none.fl_str_mv Faculdade São Leopoldo Mandic
dc.source.none.fl_str_mv RGO - Revista Gaúcha de Odontologia v.70 2022
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