Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans

Detalhes bibliográficos
Autor(a) principal: Matsubara,Victor Haruo
Data de Publicação: 2015
Outros Autores: Igai,Fernando, Tamaki,Regina, Tortamano Neto,Pedro, Nakamae,Atlas Edson Moleros, Mori,Matsuyoshi
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Dental Journal
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402015000500458
Resumo: Abstract: Since the dental implant/abutment interface cannot totally seal the passage of microorganisms, the interior of implant becomes a reservoir of pathogenic microorganisms that produce and maintain chronic inflammation in the tissues around implants. Silver nanoparticles (nano-Ag) are potent and broad-spectrum antimicrobial agents. The aim of this study was to evaluate the capacity of the nano-Ag to prevent the contamination of the implant internal surface byCandida albicans, caused by the implant/abutment microgap infiltration. Thirty-six implants were used in this experiment. Three study groups were performed: experimental group (implants receiving an application of nano-Ag in their inner cavity before installation of the abutment); positive-control group (implants receiving sterile phosphate buffer saline application instead of nano-Ag) and negative-control group (implants receiving the application of nano-Ag in the inner cavity and immersed in a sterile medium). In the positive-control and experimental groups, the implants were immersed in a Candida albicans suspension. The abutments of all three groups were screwed with a 10 N torque. After 72 h of immersion inC. albicans suspension or sterile medium, the abutments were removed and the inner surface of the implants was sampled with absorbent paper cone for fungal detection. No C. albicans contamination was observed in the negative-control group. The positive-control group showed statistically higher values of colony forming units (CFUs) of C. albicans compared with the experimental group. In conclusion, silver nanoparticles reduced C. albicans colonization inside the implants, even with low torque screw abutment.
id FUNORP-1_72e7c97c39a42d176ae42c3980ace678
oai_identifier_str oai:scielo:S0103-64402015000500458
network_acronym_str FUNORP-1
network_name_str Brazilian Dental Journal
repository_id_str
spelling Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicansdental implantsnano-AgCandida albicansimplant/abutment interface.Abstract: Since the dental implant/abutment interface cannot totally seal the passage of microorganisms, the interior of implant becomes a reservoir of pathogenic microorganisms that produce and maintain chronic inflammation in the tissues around implants. Silver nanoparticles (nano-Ag) are potent and broad-spectrum antimicrobial agents. The aim of this study was to evaluate the capacity of the nano-Ag to prevent the contamination of the implant internal surface byCandida albicans, caused by the implant/abutment microgap infiltration. Thirty-six implants were used in this experiment. Three study groups were performed: experimental group (implants receiving an application of nano-Ag in their inner cavity before installation of the abutment); positive-control group (implants receiving sterile phosphate buffer saline application instead of nano-Ag) and negative-control group (implants receiving the application of nano-Ag in the inner cavity and immersed in a sterile medium). In the positive-control and experimental groups, the implants were immersed in a Candida albicans suspension. The abutments of all three groups were screwed with a 10 N torque. After 72 h of immersion inC. albicans suspension or sterile medium, the abutments were removed and the inner surface of the implants was sampled with absorbent paper cone for fungal detection. No C. albicans contamination was observed in the negative-control group. The positive-control group showed statistically higher values of colony forming units (CFUs) of C. albicans compared with the experimental group. In conclusion, silver nanoparticles reduced C. albicans colonization inside the implants, even with low torque screw abutment.Fundação Odontológica de Ribeirão Preto2015-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402015000500458Brazilian Dental Journal v.26 n.5 2015reponame:Brazilian Dental Journalinstname:Fundação Odontológica de Ribeirão Preto (FUNORP)instacron:FUNORP10.1590/0103-644020130087info:eu-repo/semantics/openAccessMatsubara,Victor HaruoIgai,FernandoTamaki,ReginaTortamano Neto,PedroNakamae,Atlas Edson MolerosMori,Matsuyoshieng2015-12-03T00:00:00Zoai:scielo:S0103-64402015000500458Revistahttps://www.scielo.br/j/bdj/https://old.scielo.br/oai/scielo-oai.phpbdj@forp.usp.br||sergio@fosjc.unesp.br1806-47600103-6440opendoar:2015-12-03T00:00Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP)false
dc.title.none.fl_str_mv Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
title Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
spellingShingle Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
Matsubara,Victor Haruo
dental implants
nano-Ag
Candida albicans
implant/abutment interface.
title_short Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
title_full Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
title_fullStr Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
title_full_unstemmed Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
title_sort Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans
author Matsubara,Victor Haruo
author_facet Matsubara,Victor Haruo
Igai,Fernando
Tamaki,Regina
Tortamano Neto,Pedro
Nakamae,Atlas Edson Moleros
Mori,Matsuyoshi
author_role author
author2 Igai,Fernando
Tamaki,Regina
Tortamano Neto,Pedro
Nakamae,Atlas Edson Moleros
Mori,Matsuyoshi
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Matsubara,Victor Haruo
Igai,Fernando
Tamaki,Regina
Tortamano Neto,Pedro
Nakamae,Atlas Edson Moleros
Mori,Matsuyoshi
dc.subject.por.fl_str_mv dental implants
nano-Ag
Candida albicans
implant/abutment interface.
topic dental implants
nano-Ag
Candida albicans
implant/abutment interface.
description Abstract: Since the dental implant/abutment interface cannot totally seal the passage of microorganisms, the interior of implant becomes a reservoir of pathogenic microorganisms that produce and maintain chronic inflammation in the tissues around implants. Silver nanoparticles (nano-Ag) are potent and broad-spectrum antimicrobial agents. The aim of this study was to evaluate the capacity of the nano-Ag to prevent the contamination of the implant internal surface byCandida albicans, caused by the implant/abutment microgap infiltration. Thirty-six implants were used in this experiment. Three study groups were performed: experimental group (implants receiving an application of nano-Ag in their inner cavity before installation of the abutment); positive-control group (implants receiving sterile phosphate buffer saline application instead of nano-Ag) and negative-control group (implants receiving the application of nano-Ag in the inner cavity and immersed in a sterile medium). In the positive-control and experimental groups, the implants were immersed in a Candida albicans suspension. The abutments of all three groups were screwed with a 10 N torque. After 72 h of immersion inC. albicans suspension or sterile medium, the abutments were removed and the inner surface of the implants was sampled with absorbent paper cone for fungal detection. No C. albicans contamination was observed in the negative-control group. The positive-control group showed statistically higher values of colony forming units (CFUs) of C. albicans compared with the experimental group. In conclusion, silver nanoparticles reduced C. albicans colonization inside the implants, even with low torque screw abutment.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402015000500458
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402015000500458
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0103-644020130087
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Fundação Odontológica de Ribeirão Preto
publisher.none.fl_str_mv Fundação Odontológica de Ribeirão Preto
dc.source.none.fl_str_mv Brazilian Dental Journal v.26 n.5 2015
reponame:Brazilian Dental Journal
instname:Fundação Odontológica de Ribeirão Preto (FUNORP)
instacron:FUNORP
instname_str Fundação Odontológica de Ribeirão Preto (FUNORP)
instacron_str FUNORP
institution FUNORP
reponame_str Brazilian Dental Journal
collection Brazilian Dental Journal
repository.name.fl_str_mv Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP)
repository.mail.fl_str_mv bdj@forp.usp.br||sergio@fosjc.unesp.br
_version_ 1754204093879943168