Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Dental Journal |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402010000500013 |
Resumo: | This study evaluated the use of zoledronic acid, a resorption inhibitor, as a medication for root resorption treatment of late replanted teeth. Twenty-four maxillary right central incisors of rats were avulsed and kept dry for 30 min. Then, the teeth were divided into 2 groups. In group I, root surface was treated with 2% sodium fluoride for 20 min; in group II, 10-6M zoledronic acid solution was used for 20 min. All root canals were filled with calcium hydroxide. Next, teeth were replanted in their respective sockets. After 15 and 60 days post-replantation, the animals were killed and the anatomic pieces were obtained and prepared for microscopic and morphometric analyses. The results showed that zoledronic acid was capable of limiting the occurrence of root resorption and preserving cementum resorption. Further research must be performed to confirm the use of zoledronic acid in root surface treatment of late replanted teeth. |
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Brazilian Dental Journal |
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Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in ratszoledronic acidroot resorptiontooth replantationThis study evaluated the use of zoledronic acid, a resorption inhibitor, as a medication for root resorption treatment of late replanted teeth. Twenty-four maxillary right central incisors of rats were avulsed and kept dry for 30 min. Then, the teeth were divided into 2 groups. In group I, root surface was treated with 2% sodium fluoride for 20 min; in group II, 10-6M zoledronic acid solution was used for 20 min. All root canals were filled with calcium hydroxide. Next, teeth were replanted in their respective sockets. After 15 and 60 days post-replantation, the animals were killed and the anatomic pieces were obtained and prepared for microscopic and morphometric analyses. The results showed that zoledronic acid was capable of limiting the occurrence of root resorption and preserving cementum resorption. Further research must be performed to confirm the use of zoledronic acid in root surface treatment of late replanted teeth.Fundação Odontológica de Ribeirão Preto2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402010000500013Brazilian Dental Journal v.21 n.5 2010reponame:Brazilian Dental Journalinstname:Fundação Odontológica de Ribeirão Preto (FUNORP)instacron:FUNORP10.1590/S0103-64402010000500013info:eu-repo/semantics/openAccessMori,Graziela GarridoJanjacomo,Daniela Maria de MendonçaNunes,Daniele ClapesCastilho,Lithiene Ribeiroeng2010-12-10T00:00:00Zoai:scielo:S0103-64402010000500013Revistahttps://www.scielo.br/j/bdj/https://old.scielo.br/oai/scielo-oai.phpbdj@forp.usp.br||sergio@fosjc.unesp.br1806-47600103-6440opendoar:2010-12-10T00:00Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP)false |
dc.title.none.fl_str_mv |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
title |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
spellingShingle |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats Mori,Graziela Garrido zoledronic acid root resorption tooth replantation |
title_short |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
title_full |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
title_fullStr |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
title_full_unstemmed |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
title_sort |
Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats |
author |
Mori,Graziela Garrido |
author_facet |
Mori,Graziela Garrido Janjacomo,Daniela Maria de Mendonça Nunes,Daniele Clapes Castilho,Lithiene Ribeiro |
author_role |
author |
author2 |
Janjacomo,Daniela Maria de Mendonça Nunes,Daniele Clapes Castilho,Lithiene Ribeiro |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Mori,Graziela Garrido Janjacomo,Daniela Maria de Mendonça Nunes,Daniele Clapes Castilho,Lithiene Ribeiro |
dc.subject.por.fl_str_mv |
zoledronic acid root resorption tooth replantation |
topic |
zoledronic acid root resorption tooth replantation |
description |
This study evaluated the use of zoledronic acid, a resorption inhibitor, as a medication for root resorption treatment of late replanted teeth. Twenty-four maxillary right central incisors of rats were avulsed and kept dry for 30 min. Then, the teeth were divided into 2 groups. In group I, root surface was treated with 2% sodium fluoride for 20 min; in group II, 10-6M zoledronic acid solution was used for 20 min. All root canals were filled with calcium hydroxide. Next, teeth were replanted in their respective sockets. After 15 and 60 days post-replantation, the animals were killed and the anatomic pieces were obtained and prepared for microscopic and morphometric analyses. The results showed that zoledronic acid was capable of limiting the occurrence of root resorption and preserving cementum resorption. Further research must be performed to confirm the use of zoledronic acid in root surface treatment of late replanted teeth. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402010000500013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402010000500013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-64402010000500013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Fundação Odontológica de Ribeirão Preto |
publisher.none.fl_str_mv |
Fundação Odontológica de Ribeirão Preto |
dc.source.none.fl_str_mv |
Brazilian Dental Journal v.21 n.5 2010 reponame:Brazilian Dental Journal instname:Fundação Odontológica de Ribeirão Preto (FUNORP) instacron:FUNORP |
instname_str |
Fundação Odontológica de Ribeirão Preto (FUNORP) |
instacron_str |
FUNORP |
institution |
FUNORP |
reponame_str |
Brazilian Dental Journal |
collection |
Brazilian Dental Journal |
repository.name.fl_str_mv |
Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP) |
repository.mail.fl_str_mv |
bdj@forp.usp.br||sergio@fosjc.unesp.br |
_version_ |
1754204091410546688 |