Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos

Detalhes bibliográficos
Autor(a) principal: Lopes, Carolina Rosa
Data de Publicação: 2010
Outros Autores: D'Oca, Caroline Da Ros Montes, Duarte, Rodrigo da Costa, Kurz, Márcia Helena Scherer, Primel, Ednei Gilberto, Clementin, Rosilene Maria, Villarreyes, Joaquín Ariel Morón, D'Oca, Marcelo Gonçalves Montes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FURG (RI FURG)
Texto Completo: http://repositorio.furg.br/handle/1/1653
Resumo: Recent biochemical and pharmacological studies have led to the characterization of different fatty acid amides as a new family of biologically active lipids. Here, we describe the synthesis of new amides from C16:0, 18:0, 18:1 and 18:1, OH fatty acids (FFA) families with cyclic and acyclic amines and demonstrate for the first time that these compounds produce citotoxic effects. Application of this method to the synthesis of fatty acid amides was performed using the esters aminolysis as a key step and various carboxylic amides were prepared in good yield from fatty acid methyl esters (FAMEs).
id FURG_225037bf518ad7bcc05eb95e39a2177d
oai_identifier_str oai:repositorio.furg.br:1/1653
network_acronym_str FURG
network_name_str Repositório Institucional da FURG (RI FURG)
repository_id_str
spelling Síntese de novas amidas graxas a partir da aminólise de ésteres metílicosSynthesis of new fatty acids amides from aminolysis of famesAnandamideRicinoleic amidesFAMEsRecent biochemical and pharmacological studies have led to the characterization of different fatty acid amides as a new family of biologically active lipids. Here, we describe the synthesis of new amides from C16:0, 18:0, 18:1 and 18:1, OH fatty acids (FFA) families with cyclic and acyclic amines and demonstrate for the first time that these compounds produce citotoxic effects. Application of this method to the synthesis of fatty acid amides was performed using the esters aminolysis as a key step and various carboxylic amides were prepared in good yield from fatty acid methyl esters (FAMEs).2011-12-29T21:56:17Z2011-12-29T21:56:17Z2010info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfLOPES, Carolina Rosa et al. Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos. Química Nova, São Paulo, v. 33, n. 6, p. 1335-1341, 2010. Disponível em: <http://www.scielo.br/pdf/qn/v33n6/22.pdf> Acesso em: 29 dez. 2011.0100-4042http://repositorio.furg.br/handle/1/1653porLopes, Carolina RosaD'Oca, Caroline Da Ros MontesDuarte, Rodrigo da CostaKurz, Márcia Helena SchererPrimel, Ednei GilbertoClementin, Rosilene MariaVillarreyes, Joaquín Ariel MorónD'Oca, Marcelo Gonçalves Montesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FURG (RI FURG)instname:Universidade Federal do Rio Grande (FURG)instacron:FURG2019-11-14T02:03:35Zoai:repositorio.furg.br:1/1653Repositório InstitucionalPUBhttps://repositorio.furg.br/oai/request || http://200.19.254.174/oai/requestopendoar:2019-11-14T02:03:35Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)false
dc.title.none.fl_str_mv Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
Synthesis of new fatty acids amides from aminolysis of fames
title Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
spellingShingle Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
Lopes, Carolina Rosa
Anandamide
Ricinoleic amides
FAMEs
title_short Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
title_full Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
title_fullStr Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
title_full_unstemmed Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
title_sort Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos
author Lopes, Carolina Rosa
author_facet Lopes, Carolina Rosa
D'Oca, Caroline Da Ros Montes
Duarte, Rodrigo da Costa
Kurz, Márcia Helena Scherer
Primel, Ednei Gilberto
Clementin, Rosilene Maria
Villarreyes, Joaquín Ariel Morón
D'Oca, Marcelo Gonçalves Montes
author_role author
author2 D'Oca, Caroline Da Ros Montes
Duarte, Rodrigo da Costa
Kurz, Márcia Helena Scherer
Primel, Ednei Gilberto
Clementin, Rosilene Maria
Villarreyes, Joaquín Ariel Morón
D'Oca, Marcelo Gonçalves Montes
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Carolina Rosa
D'Oca, Caroline Da Ros Montes
Duarte, Rodrigo da Costa
Kurz, Márcia Helena Scherer
Primel, Ednei Gilberto
Clementin, Rosilene Maria
Villarreyes, Joaquín Ariel Morón
D'Oca, Marcelo Gonçalves Montes
dc.subject.por.fl_str_mv Anandamide
Ricinoleic amides
FAMEs
topic Anandamide
Ricinoleic amides
FAMEs
description Recent biochemical and pharmacological studies have led to the characterization of different fatty acid amides as a new family of biologically active lipids. Here, we describe the synthesis of new amides from C16:0, 18:0, 18:1 and 18:1, OH fatty acids (FFA) families with cyclic and acyclic amines and demonstrate for the first time that these compounds produce citotoxic effects. Application of this method to the synthesis of fatty acid amides was performed using the esters aminolysis as a key step and various carboxylic amides were prepared in good yield from fatty acid methyl esters (FAMEs).
publishDate 2010
dc.date.none.fl_str_mv 2010
2011-12-29T21:56:17Z
2011-12-29T21:56:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv LOPES, Carolina Rosa et al. Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos. Química Nova, São Paulo, v. 33, n. 6, p. 1335-1341, 2010. Disponível em: <http://www.scielo.br/pdf/qn/v33n6/22.pdf> Acesso em: 29 dez. 2011.
0100-4042
http://repositorio.furg.br/handle/1/1653
identifier_str_mv LOPES, Carolina Rosa et al. Síntese de novas amidas graxas a partir da aminólise de ésteres metílicos. Química Nova, São Paulo, v. 33, n. 6, p. 1335-1341, 2010. Disponível em: <http://www.scielo.br/pdf/qn/v33n6/22.pdf> Acesso em: 29 dez. 2011.
0100-4042
url http://repositorio.furg.br/handle/1/1653
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da FURG (RI FURG)
instname:Universidade Federal do Rio Grande (FURG)
instacron:FURG
instname_str Universidade Federal do Rio Grande (FURG)
instacron_str FURG
institution FURG
reponame_str Repositório Institucional da FURG (RI FURG)
collection Repositório Institucional da FURG (RI FURG)
repository.name.fl_str_mv Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)
repository.mail.fl_str_mv
_version_ 1813187262511316992

Registros relacionados