Lipid peroxidation induced by Clinostomum detruncatum in muscle of the freshwater fish Rhamdia quelen

• Autor(a) principal: Belló, André Ricardo Ribeiro
• Data de Publicação: 2000
• Outros Autores: Fortes, Elinor, Klein, Adriane Belló, Belló, Antonio Andréa, Llesuy, Susana Francisca, Robaldo, Ricardo Berteaux, Bianchini, Adalto
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da FURG (RI FURG)
• Texto Completo: http://repositorio.furg.br/handle/1/5395
• topic: Parasite; Oxidative stress; Lipid peroxidation; Fish

The effect of Clinostomum detruncatum metacercaria infection on the activities of the antioxidant enzymes superoxide dismutase and catalase in muscle of the freshwater fish Rhamdia quelen was analyzed. Tert-butyl hydroperoxide-initiated chemiluminescence, a measure of lipid peroxidation, was also investigated. Enzyme activities were similar in infected and uninfected fishes. However, the chemiluminescence was almost 2-fold higher in muscle of infected fishes than in muscle of uninfected ones. These results indicate that parasite infection induces oxidative stress and a higher level of membrane damage in the fish muscle due to an imbalance between pro-oxidants and non-enzymatic antioxidants. Our results suggest that fish response to parasite infection could involve, as in other vertebrates, reactive oxygen intermediates