OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Implantology and Health Sciences |
Texto Completo: | https://bjihs.emnuvens.com.br/bjihs/article/view/1609 |
Resumo: | Introduction: Opiates are substances derived from the poppy plant, whose site of action is the opioid receptors. Opioids include substances, natural or synthetic, endogenous or exogenous, which also interact with opioid receptors, such as mu, kappa, delta and sigma, present throughout the body, generating manifestations in various systems. This study aims to address the pathophysiology and management of thermal burns. Methods: In the literature review, PubMed and Google Scholar databases were consulted, using the descriptors "opioid overdose", "diagnosis" and "management", resulting in 600 studies. Of these, 18 were selected for their relevance to the topic and publication in English or Portuguese. Results: Chronic use of opioids can induce use disorder, characterized by persistent craving, increased tolerance and withdrawal syndrome. Overdose occurs due to hyperstimulation of the opioid pathway, either by intentional increase or developed tolerance. During overdose, signs include hypothermia, bradycardia and limited response or unconsciousness, making witness reports and analysis of the environment vital. Pre-hospital management includes naloxone administration, airway protection and support, while the hospital environment follows the ABCDE protocol, with higher doses of naloxone and additional diagnostic procedures. Conclusion: Due to the epidemic that has become opioid overdose, it is necessary for health professionals to be prepared to deal with such an occurrence. |
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OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS OPIOIDES: TRATAMIENTO DE LAS SOBREDOSIS Y CONSIDERACIONES CLÍNICASOPIOIDES: MANEJO DA OVERDOSE E CONSIDERAÇÕES CLÍNICASOverdoseOpioideAtenção médicaOverdoseOpioidMedical careSobredosisOpiáceosAtención médicaIntroduction: Opiates are substances derived from the poppy plant, whose site of action is the opioid receptors. Opioids include substances, natural or synthetic, endogenous or exogenous, which also interact with opioid receptors, such as mu, kappa, delta and sigma, present throughout the body, generating manifestations in various systems. This study aims to address the pathophysiology and management of thermal burns. Methods: In the literature review, PubMed and Google Scholar databases were consulted, using the descriptors "opioid overdose", "diagnosis" and "management", resulting in 600 studies. Of these, 18 were selected for their relevance to the topic and publication in English or Portuguese. Results: Chronic use of opioids can induce use disorder, characterized by persistent craving, increased tolerance and withdrawal syndrome. Overdose occurs due to hyperstimulation of the opioid pathway, either by intentional increase or developed tolerance. During overdose, signs include hypothermia, bradycardia and limited response or unconsciousness, making witness reports and analysis of the environment vital. Pre-hospital management includes naloxone administration, airway protection and support, while the hospital environment follows the ABCDE protocol, with higher doses of naloxone and additional diagnostic procedures. Conclusion: Due to the epidemic that has become opioid overdose, it is necessary for health professionals to be prepared to deal with such an occurrence.Introducción: Los opiáceos son sustancias derivadas de la planta de amapola, cuyo sitio de acción son los receptores opioides. Los opiáceos incluyen sustancias, naturales o sintéticas, endógenas o exógenas, que también interactúan con los receptores opioides, como mu, kappa, delta y sigma, presentes en todo el organismo, generando manifestaciones en diversos sistemas. Este estudio pretende abordar la fisiopatología y el manejo de las quemaduras térmicas. Métodos: En la revisión bibliográfica se consultaron las bases de datos PubMed y Google Scholar, utilizando los descriptores "opioid overdose", "diagnosis" y "management", obteniéndose 600 estudios. De estos, 18 fueron seleccionados por su relevancia para el tema y publicación en inglés o portugués. Resultados: El uso crónico de opioides puede inducir un trastorno por consumo, caracterizado por un deseo persistente, aumento de la tolerancia y síndrome de abstinencia. La sobredosis ocurre debido a la hiperestimulación de la vía opioide, ya sea por aumento intencional o por tolerancia desarrollada. Durante la sobredosis, los signos incluyen hipotermia, bradicardia y respuesta limitada o inconsciencia, por lo que son vitales los informes de testigos y el análisis del entorno. El tratamiento prehospitalario incluye la administración de naloxona y la protección y soporte de las vías respiratorias, mientras que en el entorno hospitalario se sigue el protocolo ABCDE, con dosis más altas de naloxona y procedimientos diagnósticos adicionales. Conclusiones: Debido a la epidemia en que se ha convertido la sobredosis de opioides, es necesario que los profesionales sanitarios estén preparados para hacer frente a un suceso de este tipo.Introdução: Opiáceos são substâncias derivadas da planta papoula, cujo sítio de ação são os receptores opiáceos. Já os opioides englobam substâncias, naturais ou sintéticas, endógenas ou exógenas, que também interagem com os receptores opióides, como o mu, kappa, delta e sigma, presentes em todo o organismo, gerando manifestações em diversos sistemas. Este estudo tem por objetivo abordar a fisiopatologia e o manejo da queimadura térmica. Métodos: Na revisão de literatura, foram consultados os bancos de dados PubMed e Google Scholar, utilizando os descritores "opioid overdose", "diagnosis" e "management", resultando em 600 estudos. Desses, 18 foram selecionados por relevância ao tema e publicação em inglês ou português. Resultados: O uso crônico de opioides pode induzir ao transtorno de uso, caracterizado pelo desejo persistente, aumento de tolerância e síndrome de abstinência. A overdose ocorre pela hiperestimulação da via opiácea, seja por aumento intencional ou tolerância desenvolvida. Durante a overdose, os sinais incluem hipotermia, bradicardia e resposta limitada ou inconsciência, tornando vital o relato de testemunhas e análise do ambiente. O manejo pré-hospitalar inclui administração de naloxona, proteção da via aérea e suporte, enquanto o ambiente hospitalar segue o protocolo ABCDE, com doses maiores de naloxona e procedimentos diagnósticos adicionais. Conclusão: Devido a epidemia que virou a overdose por uso de opioides, é necessário que profissionais da saúde estejam preparados para lidar com tal ocorrência.Specialized Dentistry Group2024-03-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://bjihs.emnuvens.com.br/bjihs/article/view/160910.36557/2674-8169.2024v6n3p463-474Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 3 (2024): BJIHS QUALIS B3; 463-474Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 3 (2024): BJIHS QUALIS B3; 463-474Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 3 (2024): BJIHS QUALIS B3; 463-4742674-8169reponame:Brazilian Journal of Implantology and Health Sciencesinstname:Grupo de Odontologia Especializada (GOE)instacron:GOEporhttps://bjihs.emnuvens.com.br/bjihs/article/view/1609/1801Copyright (c) 2024 Marina Pezzetti Sanchez Diogo, Natália Henriques da Fonseca Araújo, Humberto Novais da Conceição, Isadora Gabriela Cella Decian, Gustavo Santin Boti, Camila Cataneo Cardoso Borin, Victor Hugo Sardinha de Freitas, Milagres Araújo Nascimento, Leonardo Maquiné Hermont, Thays Depieri Abrão de Campos, Gabriella Baldin de Miranda Andrade , José Noleto Sales Neto, Natália Henriques da Fonseca Araújo, Emmanoel de Jesus Siquara Netohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPezzetti Sanchez Diogo, MarinaHenriques da Fonseca Araújo, NatáliaNovais da Conceição, HumbertoGabriela Cella Decian, IsadoraSantin Boti, GustavoCataneo Cardoso Borin, CamilaHugo Sardinha de Freitas, VictorAraújo Nascimento, MilagresMaquiné Hermont, LeonardoDepieri Abrão de Campos, ThaysBaldin de Miranda Andrade , GabriellaNoleto Sales Neto, JoséHenriques da Fonseca Araújo, Natáliade Jesus Siquara Neto, Emmanoel2024-03-07T20:29:44Zoai:ojs.bjihs.emnuvens.com.br:article/1609Revistahttps://bjihs.emnuvens.com.br/bjihsONGhttps://bjihs.emnuvens.com.br/bjihs/oaijournal.bjihs@periodicosbrasil.com.br2674-81692674-8169opendoar:2024-03-07T20:29:44Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE)false |
dc.title.none.fl_str_mv |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS OPIOIDES: TRATAMIENTO DE LAS SOBREDOSIS Y CONSIDERACIONES CLÍNICAS OPIOIDES: MANEJO DA OVERDOSE E CONSIDERAÇÕES CLÍNICAS |
title |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS |
spellingShingle |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS Pezzetti Sanchez Diogo, Marina Overdose Opioide Atenção médica Overdose Opioid Medical care Sobredosis Opiáceos Atención médica |
title_short |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS |
title_full |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS |
title_fullStr |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS |
title_full_unstemmed |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS |
title_sort |
OPIOIDS: OVERDOSE MANAGEMENT, AND CLINICAL CONSIDERATIONS |
author |
Pezzetti Sanchez Diogo, Marina |
author_facet |
Pezzetti Sanchez Diogo, Marina Henriques da Fonseca Araújo, Natália Novais da Conceição, Humberto Gabriela Cella Decian, Isadora Santin Boti, Gustavo Cataneo Cardoso Borin, Camila Hugo Sardinha de Freitas, Victor Araújo Nascimento, Milagres Maquiné Hermont, Leonardo Depieri Abrão de Campos, Thays Baldin de Miranda Andrade , Gabriella Noleto Sales Neto, José de Jesus Siquara Neto, Emmanoel |
author_role |
author |
author2 |
Henriques da Fonseca Araújo, Natália Novais da Conceição, Humberto Gabriela Cella Decian, Isadora Santin Boti, Gustavo Cataneo Cardoso Borin, Camila Hugo Sardinha de Freitas, Victor Araújo Nascimento, Milagres Maquiné Hermont, Leonardo Depieri Abrão de Campos, Thays Baldin de Miranda Andrade , Gabriella Noleto Sales Neto, José de Jesus Siquara Neto, Emmanoel |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Pezzetti Sanchez Diogo, Marina Henriques da Fonseca Araújo, Natália Novais da Conceição, Humberto Gabriela Cella Decian, Isadora Santin Boti, Gustavo Cataneo Cardoso Borin, Camila Hugo Sardinha de Freitas, Victor Araújo Nascimento, Milagres Maquiné Hermont, Leonardo Depieri Abrão de Campos, Thays Baldin de Miranda Andrade , Gabriella Noleto Sales Neto, José Henriques da Fonseca Araújo, Natália de Jesus Siquara Neto, Emmanoel |
dc.subject.por.fl_str_mv |
Overdose Opioide Atenção médica Overdose Opioid Medical care Sobredosis Opiáceos Atención médica |
topic |
Overdose Opioide Atenção médica Overdose Opioid Medical care Sobredosis Opiáceos Atención médica |
description |
Introduction: Opiates are substances derived from the poppy plant, whose site of action is the opioid receptors. Opioids include substances, natural or synthetic, endogenous or exogenous, which also interact with opioid receptors, such as mu, kappa, delta and sigma, present throughout the body, generating manifestations in various systems. This study aims to address the pathophysiology and management of thermal burns. Methods: In the literature review, PubMed and Google Scholar databases were consulted, using the descriptors "opioid overdose", "diagnosis" and "management", resulting in 600 studies. Of these, 18 were selected for their relevance to the topic and publication in English or Portuguese. Results: Chronic use of opioids can induce use disorder, characterized by persistent craving, increased tolerance and withdrawal syndrome. Overdose occurs due to hyperstimulation of the opioid pathway, either by intentional increase or developed tolerance. During overdose, signs include hypothermia, bradycardia and limited response or unconsciousness, making witness reports and analysis of the environment vital. Pre-hospital management includes naloxone administration, airway protection and support, while the hospital environment follows the ABCDE protocol, with higher doses of naloxone and additional diagnostic procedures. Conclusion: Due to the epidemic that has become opioid overdose, it is necessary for health professionals to be prepared to deal with such an occurrence. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-03-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/1609 10.36557/2674-8169.2024v6n3p463-474 |
url |
https://bjihs.emnuvens.com.br/bjihs/article/view/1609 |
identifier_str_mv |
10.36557/2674-8169.2024v6n3p463-474 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/1609/1801 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Specialized Dentistry Group |
publisher.none.fl_str_mv |
Specialized Dentistry Group |
dc.source.none.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 3 (2024): BJIHS QUALIS B3; 463-474 Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 3 (2024): BJIHS QUALIS B3; 463-474 Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 3 (2024): BJIHS QUALIS B3; 463-474 2674-8169 reponame:Brazilian Journal of Implantology and Health Sciences instname:Grupo de Odontologia Especializada (GOE) instacron:GOE |
instname_str |
Grupo de Odontologia Especializada (GOE) |
instacron_str |
GOE |
institution |
GOE |
reponame_str |
Brazilian Journal of Implantology and Health Sciences |
collection |
Brazilian Journal of Implantology and Health Sciences |
repository.name.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE) |
repository.mail.fl_str_mv |
journal.bjihs@periodicosbrasil.com.br |
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