Autoimmune Hepatitis: Exploring the Pathways of the Immune Response Against the Liver.

• Autor(a) principal: Sousa, George Oliveira de
• Data de Publicação: 2024
• Outros Autores: Sousa, Andressa Campos de, Alves , Caio Márcio Coelho, Camargo, Júlia Beatriz de Carvalho, Rizzi , Ana Paula, Braide , Carlos Victor Santos, Ferreira, Iago Lucas dos Santos, Macêda, Isabelle Oliveira, França , Antonia Georgia Oliveira, Filho , Júlio Abdala Calil, Nunes , Maria Clara Pereira prado
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1000
• topic: Hepatite, Autoimune, Hepatite Autoimune, Sistema Imunológico, Prevalência e Epidemiologia; Hepatitis, Autoimmune, Autoimmune Hepatitis, Immunologic System, Prevalence, and Epidemiology

Introduction: Autoimmune hepatitis, a complex and challenging condition of the hepatic system, has garnered increasing interest in the scientific community due to its multifaceted nature and significant implications for human health. This inflammatory liver disease, characterized by an autoimmune response directed against hepatocytes, presents a unique complexity in both its etiology and clinical manifestations. Methodology: The methodology employed for this literature review on autoimmune hepatitis involved a comprehensive search for scientific articles, beginning on 01/08/2023 and concluding on 12/01/2023. The search was conducted using English descriptors specific to the Medical Subject Headings (MeSH), focusing on Hepatitis, Autoimmune, Autoimmune Hepatitis, Immunologic System, Prevalence, and Epidemiology. Results: The higher prevalence of women affected by autoimmune hepatitis stands among the most pronounced in autoimmune conditions. However, the underlying mechanisms behind gender disparities in autoimmune liver diseases still remain exclusively unknown. Conclusion: It is crucial that patients with autoimmune hepatitis receive regular health team follow-up to monitor the progression of the disease and adjust the treatment as necessary.