EFFECT OF IRRIGATION SOLUTIONS USED IN REGE ENDODONTICS ON STEM CELLS OF DENTAL ORIGIN: LITERATURE REVIEW

• Autor(a) principal: Ferreira , Antônio Fabricio Alves
• Data de Publicação: 2023
• Outros Autores: Brito , Sávio José da Silva, Guimarães , Samara de Freitas, Andrade , Renato Leonardo Santos de, Lima , Mabel Martins, Lima, Emanuela Carolaine Teixeira, Santana, Késia Zamerim, Lau , Pedro Lucas de Carvalho, Pereira , Katia Caetana, Monteiro , Vinicius Ribeiro
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/925
• topic: Células tronco, Soluções irrigadoras, Endodontia.

Stem cells derived from teeth act in the maintenance of pulp homeostasis, in addition to having high plasticity and pluripotency. It is worth mentioning that the apical papilla region is full of mesenchymal stem cells (SCAPs), which can survive endodontic infection, and jointly with Hertwig's epithelial root sheath, they direct root development. Therefore, regenerative endodontic therapies are necessary for immature teeth to maintain the viability of these structures and ensure the complete root maturation process. Regenerative endodontic therapy is still evolving, lacking evidence from translational and clinical research to support informed physician choice regarding the best therapeutic irrigation protocol to promote the release of dentin growth factors and tissue repair. Furthermore, clinical studies inherent heterogeneity and complexity have hampered the evaluation of data on the release of growth factors during regenerative endodontic therapies.